Caroline

behavioral pharmacologist, neuroscientist, addiction and motivation circuits, AAV and gene therapy. Mom of two little scientists.

[Caroline @CarolineEBass]

@drugmonkeyblog It gave me the ick, but I guess it sounds good to lay people?

[Denise J. Cai, Ph.D. @denisejcai]

What’s better than a one-channel #Miniscope? 🥁 A TWO-CHANNEL Miniscope!

Our new Miniscope2C is a dual-channel, open-source Miniscope that lets you record 2 fluorescent signals simultaneously in freely moving animals.

Read the paper here:
https://t.co/LchmY020Rw

(1/9)

[Caroline @CarolineEBass]

Seriously, this message has to get out there. Without academic research we can’t produce the PhD and MS level scientists that drive scientific innovation in the private sector.

[Bita Moghaddam بيتا مقدم @bita137]

Many in biotech/private sector are boasting about their ways of funding and doing science

But they are staffed with PhDs and postdocs we train in our @NIH and @NSF funded labs in universities

With uni labs lacking funds to train, the private sector will be profoundly harmed

[Caroline @CarolineEBass]

I have never been so glad I am at a public university with a salary backed by hard money.

[Caroline @CarolineEBass]

Always nice to see more biosensors out there!

[Yulong Li Lab @yulonglilab]

(1/6) Excited to introduce our first generation red acetylcholine sensors! #acetylcholine #GRAB #RedSensors
https://t.co/QR21demIHG

[Caroline @CarolineEBass]

Sweet, can’t wait to set one of these up!

[Yulong Li Lab @yulonglilab]

(1/7) Far-red dopamine sensor is coming! Excited to introduce our chemigenetic DA sensor, HaloDA1.0! #Dopamine #FarRedSensors, #GRAB https://t.co/hvFwIO6BWh

[Joachim Schork @JoachimSchork]

The Kruskal-Wallis test is a non-parametric method used to determine if there are statistically significant differences in the distributions of three or more independent groups based on ranks. Unlike ANOVA, it does not assume a normal distribution, making it versatile for analyzing non-normally distributed data sets.

Advantages of Proper Use:
✔️ Suitable for ordinal data or non-normally distributed data sets.
✔️ Does not assume homogeneity of variance, offering more flexibility.
✔️ Can be used with small sample sizes, increasing its applicability in various research settings.

Challenges If Not Handled Correctly:
❌ Interpretation can be complex, especially if the test is mistaken for a direct comparison of medians when specific conditions aren't met (e.g., independent samples, symmetric distributions).
❌ Less powerful than ANOVA when data is normally distributed, which can lead to less accurate results.
❌ May require post-hoc tests to pinpoint specific group differences, adding complexity to the analysis.

How to Apply in Practice:
🔹 R: Use the kruskal.test() function from the base package to perform the Kruskal-Wallis test.
🔹 Python: Utilize the kruskal() function from the scipy.stats module for the analysis.
Visualization Explanation:

The visualization accompanying this post compares ANOVA and the Kruskal-Wallis test by ranks. This visualization is adapted from a Wikipedia source: https://t.co/1hRzGEFOjY

For those interested in learning more, consider joining my online course on Statistical Methods in R, where we explore this topic and related methods in greater detail.

Take a look here for more details: https://t.co/7YQCRDKSPO

#DataAnalytics #RStats #Rpackage #DataScientist

[Caroline @CarolineEBass]

Just did my once a semester demonstration of how quickly I can get information by calling tech support, not texting or emailing them but actually having a conversation…I don’t think I convinced my students 🙃

[Caroline @CarolineEBass]

Since my sister couldn’t wear her #Kamala4President shirts to vote, she dressed in sneakers, jeans, blouse, navy jacket and pearls…

[Caroline @CarolineEBass]

Look what I found in the back of my closet, times have certainly changed since I was a grad student @ToxVcu

[Caroline @CarolineEBass]

Don’t most programs provide a waiver if you ask?

[Cientifico Latino, Inc. @cientificolatin]

Grad school apps are EXPENSIVE....💸

So, which #STEM PhD programs have WAIVED their application fee this year?!

We have compiled a list of programs that you can apply to for FREE. Please let us know if you’ve heard of others! Thank you!!💜

https://t.co/d6SwodFpSR

[Caroline @CarolineEBass]

Wow!!!

[Schuh Lab @SchuhLab]

Each month an #egg is ovulated from the #ovary, starting the journey of reproduction. But how does ovulation occur?🥚

Our latest work in @NatureCellBio led by @LastChrisThomas and @Tabea_Marx, describes the control of #ovulation using live imaging.

https://t.co/EYjwLfdAdy (1/7)

[Caroline @CarolineEBass]

@CterminiPhD It usually takes me 3-4 years to work the last place out of my system.

[Liz Chrastil @chrastil]

A few years ago I was in a position to do something unique in neuroscience. I had been working with the phenomenal @emilyjacobs on menopause and inspired by @laura_pritschet's menstrual study, and I was planning a pregnancy. What if we scanned my brain??
https://t.co/mTLfToPhru

[Carrie Ferrario @FerrarioLab]

Come be my colleague @SSIBsociety @ACNPorg @BlackInNeuro @SACNAS

[Dr. Melissa Sharpe @MelissaJSharpe]

🔥New Paper from the lab! Led by @mtaira_723 and our awesome team, we reveal the learning components signaled by dopamine release in the Nucleus Accumbens core (NAcC): https://t.co/T6n1TUaFoK

[Prof. Michael Lin @MichaelLinLab]

Congrats to my friend and colleague Guosong Hong for his stunning and original discovery, published today in Science, on clearing tissues *in living animals* with a common food dye!

The dye is tartrazine, used in Doritos!

https://t.co/fqVivyH0kI

[Caroline @CarolineEBass]

@stephjhuang @KESchoonover1 Damn that looks good, now I need to figure out a reason to do this stain..!

[Caroline @CarolineEBass]

@mike_feigin Just one box?