Wonderful visit from Gabriel Neurohr from @ETH to our department this week! Great science and inspiring discussions with faculty and students! Thanks @GabrielNeurohr, for the fantastic @EMBO_YIP Lecture at @kocuniversity@KocSciences. Thanks to @EMBO_YIP for making this possible!
Gautam Dey (@Dey_Gautam, @embl) delivered a fantastic @EMBO_YIP Lecture today as part of the MBGE Seminar Series at @KocSciences@kocuniversity.
Thank you for the energy, enthusiasm, and inspiration you shared with us and our students!
Excited to share our new preprint on @biorxivpreprint!
We show that USP28 mutations found in cancer block its interaction with 53BP1, disrupting p53 stabilization. Check out the full story...
https://t.co/t7XbfY3cID
Preprint: IntAct-U-ExM enables robust, isoform-specific expansion microscopy of actin networks in yeast and mammalian cells. A cool study led by @anubhav_dhar in collab with @Sudiya14@deepak_iisc#actin https://t.co/GTTRUF8dGC
Spotlight: Kane @UpstateNews discusses new work from @MaryHuda97 et al. @CaydasiLab (https://t.co/csg8P8EyKM) showing that in S. cerevisiae transient cell cycle–dependent asymmetry in PI(3,5)P2 levels promotes vacuolar acidification in daughter cells. https://t.co/p02iARESoj
Spotlight: Kane @UpstateNews discusses new work from @MaryHuda97 et al. @CaydasiLab (https://t.co/csg8P8EyKM) showing that in S. cerevisiae transient cell cycle–dependent asymmetry in PI(3,5)P2 levels promotes vacuolar acidification in daughter cells. https://t.co/p02iARESoj
🚨 Attention PhD students & postdocs! Last chance to apply for the FEBS Young Scientists’ Forum in Sapanca, Türkiye (2–5 July 2025). Present your research, network with peers, and learn from top scientists.
🗓 Apply by Dec 12, 23:59 (UTC+01:00). https://t.co/R18rbMgBq7
#youngFEBS
How do organelles fit together inside a crowded cell? Answering this question requires a way to image many organelles in a whole cell at high resolution with high throughput. Our new preprint shows how to do this in yeast using soft x-ray tomography
https://t.co/PbRajXb9sj
@MaryHuda97 et al. @CaydasiLab@kocuniversity show that asymmetric PI(3,5)P2 synthesis is crucial for vacuolar-pH asymmetry and provide insights into how the mother cell ages while the daughter cell is rejuvenated in budding yeast https://t.co/WhJNLm45UP
#Mitosis#CellSignaling
Job Alert! Our department, Department of Molecular Biology and Genetics at Koç University in Istanbul, has an open faculty position! Apply at https://t.co/Ki3jXkjHBh
@kocuniversity@KocSciences
🚨Job Alert 🚨 @KocSciences Department of Molecular Biology and Genetics is hiring tenure track faculty. The call is broad and many different fields of biology will be considered. Join an incredible Department with great colleagues here in beautiful Istanbul!
We further showed that the asymmetry of PI(3,5)P2 and the PI(3,5)P2 effector Atg18 determine the asymmetry of vacuolar pH. Given the link between vacuole acidity and longevity, our results suggest that PI(3,5)P2 is key for daughter cell rejuvenation and mother cell aging.
@MaryHuda97 et al. @CaydasiLab@Kocuniversity reveal the dynamics of the vacuolar signaling lipid PI(3,5)P2 in budding yeast. PI(3,5)P2 synthesis is asymmetric during #mitosis and plays a key role in establishing vacuolar pH asymmetry. https://t.co/jDxyFim1j6
#Lipids
Employing a ratiometric in vivo vacuolar-pH sensor, we observed a pH drop in the daughter vacuole, while a pH increase in the mother vacuole, concomitant with changes in PI(3,5)P2 distribution during mitosis.