Chiara Merigliano

Postdoc in the @chiolo_lab at @USC | Passionate about DNA damage, nuclear organization, chromatin dynamics and phase separation.

[Chiara Merigliano @ChMerigliano]

Excited to share our new paper on the fascinating role of Nup98 condensates in heterochromatin DNA repair, from the @chiolo_lab, just published in @MolecularCell! Huge congrats to all the co-authors! Check it out https://t.co/SIksy1HRYg

[Molecular Cell @MolecularCell]

Online Now: Off-pore Nup98 condensates mobilize heterochromatic breaks and exclude Rad51 https://t.co/ihrrMySRgA

[Alberto Marin-Gonzalez @AlbertoMarinG1]

How do chromatin loops help repair our genome?
Check out the review article that @taekjip and I wrote on the topic!
https://t.co/BPhItInxQV

[Molecular Cell @MolecularCell]

Online Now: RNA reinforces condensate nucleation on chromatin to amplify oncogenic transcription https://t.co/vI4MI1ipCo

[Taekjip Ha @taekjip]

Cohesin activity accelerates the homology search https://t.co/pcxkC77Tev

[Zha Lab @zha_lab]

Are you ready for the Summer? Social DNAing is! Check out the 2026 Summer line-up! Please note one schedule change on June 4th, 2026. Please RT! Sign up at https://t.co/XaGM9LsycS

[Peter Ly @PeterLyLab]

Excited to share our latest paper, out today @CellCellPress. We found that large pieces of the human genome can transfer between cells upon direct contact, endowing recipient cells with heritable phenotypic changes. (1/7)

https://t.co/SbshGhofN0

[Science in Boston @ScienceinBoston]

A new study from the lab of Dr. @Anders_S_Hansen at @MIT suggests that #chromatin moves in distinct ways that help regulate gene expression and DNA repair, revealing how genes interact within the crowded nucleus over timescales from microseconds to hours. 🧬⏳

Read more: https://t.co/xxIhXGxmgM

[Takashi Fukaya @FukayaLab]

New preprint alert! Together with Tetsuya Yamamoto at Hokkaido University, we propose a “polymer micelle” model of transcriptional bursting. https://t.co/tw2FMdpWuz

[Effie Apostolou @efapostolou29]

Excited to share our new paper in @NatureGenet led by the incredible @6jinLee! We uncover how cohesin loss impairs postmitotic refolding of 3D chromatin topology with limited context-specific effects on gene activation—especially during differentiation. https://t.co/sCPSDjAa8a

[Uli Rass @uli_rass]

Now in press: We have identified a phospho-activated RPA-binding module in Pol delta which promotes BIR. This provides a paradigm for the dynamic regulation of DNA transactions involving single-stranded intermediates bound by RPA! https://t.co/6ZB1dSJZX1

[Ksenia Krupina @krupina_lab]

Hiring in my new lab! 🧬

We study how chromosomes catastrophically fragment in cancer and how genome instability drives evolution.

Looking for a post-bac trainee planning grad school (PhD)
Lots of imaging, genetics & mechanistic biology 🔬

Apply: https://t.co/aeQKuKnabJ

[nature @Nature]

Nature research paper: An integrated view of the structure and function of the human 4D nucleome

https://t.co/PNUia4c0CH

[Chiara Merigliano @ChMerigliano]

@krupina_lab @uiowa Congratulations Ksenia!

[Chiara Merigliano @ChMerigliano]

A tale of two forms of cohesin in DNA repair

[Science Magazine @ScienceMagazine]

Extrusive and cohesive cohesin cooperate to repair double-strand breaks in DNA.

Learn more in a new #SciencePerspective: https://t.co/DTKO1zFVpJ

[HHMI @hhmi_science]

(1/2): Using cryo-electron tomography and an instrument like this one, HHMI Investigator Michael Rosen & team (not pictured) have captured the most detailed images to date of the molecules inside chromatin condensates. https://t.co/QvaWxxMIAr

[Alberto Marin-Gonzalez @AlbertoMarinG1]

Thrilled to share that my postdoc research is published today in @ScienceMagazine !! We found that DNA repair uses cohesin to build chromatin loops that guide the homology search and boost accurate repair! 1/n
https://t.co/DxArg8suv8

[Danve Castroverde @DanveC]

Multiscale structure of chromatin condensates explains phase separation and material properties https://t.co/DsCafTsojX

[Taekjip Ha @taekjip]

Gene-scale in vitro reconstitution reveals histone acetylation directly controls chromatin architecture | https://t.co/fnliQtTqYl

[ShorterLab @ShorterLab]

Nuclear-import receptors remodel the dilute phase to suppress phase transitions of RNA-binding proteins with prion-like domains: https://t.co/ncBLCrST8f

[Chiara Merigliano @ChMerigliano]

Nanoscale domains govern local diffusion and ageing within fused-in-sarcoma condensates. Intriguing study!

[Nature Nanotechnology @NatureNano]

New paper: Nanoscale domains govern local diffusion and ageing within fused-in-sarcoma condensates

Single-molecule tracking reveals nanoscale domains within #FUS #condensates that migrate to the condensate surface during aging, seeding ALS fibrils.

https://t.co/pxvUdPGDC5

[Taekjip Ha @taekjip]

FUS nanoclusters are a distinct state within the dilute
https://t.co/841ItLxCUn