Chloé Loiseau

👩🏻‍💻 Computational biologist passionate about global health and technology

[Nature Communications @NatureComms]

The relative transmission fitness of multidrug-resistant Mycobacterium tuberculosis in a drug resistance hotspot

@sgagneux1 @SwissTPH @ETH_BSSE @ChloeMLoiseau @TanjaStadler_CH

#tuberculosis #microbiology #AntibioticResistance

https://t.co/H3XN8CX90u

[Rock Lab 🧬🧫 @RockLabTB]

Excited to share our lab’s new pre-print, now out on @biorxiv_micrbio. https://t.co/mDjY599p1y “Mutations in rv0678 confer low-level resistance to benzothiazinone DprE1 inhibitors in M. tuberculosis” co-authored by @NickPoulton6 @AzadianZack and @_mad_lab_

[Harriet Blankson @HarrietBlankson]

Great talk by @sgagneux1 on evolution of MDR-TB strains. wrt MDR transmission we need to consider reproductive rates of the strains. @EsMyco #ESM2022

[Anita S @mitokondrion]

This #WorldTBDay we call for continued investment in #sequencing for improved genomic surveillance and diagnostics to #endTB @FINDdx @UNITAID @WHO @StopTB @StopTB_NDWG

[Chloé Loiseau @ChloeMLoiseau]

"Patients deserve better"

https://t.co/tiUR0alawN

[Swiss TPH @SwissTPH]

#WorldTBDay2022 A case-control study, unprecedented for its sample size and the real-world clinical setting, demonstrated the feasibility and potential of implementing the TAM-TB test for early TB diagnosis also in resource-limited settings. 👉https://t.co/kVcd8OCHXC #EndTB

[The Global Fund @GlobalFund]

Between 2019 and 2020, the number of people treated for TB in the countries where the @GlobalFund invests dropped by about 1 million people. #COVID19 is having a devastating impact on the fight against TB. We cannot let this happen. #FightForWhatCounts #WorldTBDay

[Chloé Loiseau @ChloeMLoiseau]

Another year, another #WorldTBDay and another 1.5 million preventable deaths.

#WorldTBDay2022 #EndTB

[World Health Organization (WHO) @WHO]

Today is #WorldTBDay.

#Tuberculosis - also known as TB - remains one of the world’s deadliest infectious killers.
Each day, over 4,100 people lose their lives to it & close to 28,000 people fall ill with this preventable & curable disease.

More: https://t.co/KTLi8LOQHf

[Chloé Loiseau @ChloeMLoiseau]

Very nice initiative 👏🏻

The 'MARIE project' is challenging our society to open up about vaginal health.

🌱 Let's support them: https://t.co/DmRgzVSq9O

🔗 https://t.co/5hIZoFMNDU

#vaginalhealth #microbiome #WomensHealth

[themarieproject_ch @themarieprojec1]

TheMarieProject believes that providing a woman with knowledge of their most intimate microbes will #empower her comfortably talk about her health and thus break #taboos or #stigma. We need your support with the first steps of our mission.
👉https://t.co/cjxTHtHFpi
#WomensHealth

[Iñaki Comas @icoes]

Why we map to an inferred pseudo-ancestral genome? When you map to H37Rv the number of "expected" SNPs is variable. When you map to ancestor the expected number is similar and we use this as a QC metric. See "impact of contamination" paper from @GaloGoig https://t.co/mdgyEvk3vF

[Ted Cohen @ted_h_cohen]

We are excited to share the results of a long-term genomic epidemiology project which included sequencing of M. tuberculosis isolates from all culture-positive TB patients over 2 years in Moldova. Full analysis is available at: https://t.co/EoPjsToOWY

[Swiss TPH @SwissTPH]

#TheMarieProject wants to raise awareness around vaginal health with initiatives including a Swiss-wide health questionnaire and microbiome screening

👉 Support the project now on @wemakeit and spread the word!

@Isala_UAntwerp @mticllacc

https://t.co/GRjkHCuRF0

[Nico Rascovan @NRascovan]

We opened a *permanent position* for an experienced #bioinformatics, to work in the analysis of microbial and human #ancientDNA data at @institutpasteur @HubPasteur #paleogenomics #phylogenomics #metagenomics #aDNA

Please spread the word!

More info here:
https://t.co/twXiEtwI8i

[The Lancet @TheLancet]

NEW—An estimated 1.2 million people died in 2019 from antibiotic-resistant bacterial infections, more deaths than HIV/AIDS or malaria.

#GRAMPaper reveals the scale of antimicrobial resistance (#AMR), now a leading cause of death worldwide: https://t.co/2h5UEKemEq #AMRSOS

[Patrick Kearns @kearnsneuro]

Phenomenal paper just published in Science persuasively demonstrating that EBV causes most if not all multiple sclerosis.

Phenomenal epidemiological design and technical achievement. 👏

https://t.co/LcNFvKHiUp

[Prof Francois Balloux @BallouxFrancois]

New study out on drug resistance in Mycobacterium tuberculosis (Mtb), the agent of tuberculosis (TB). We modelled emergence of drug resistance in the largest Mob population-genomic study to date in Lima (Peru).
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https://t.co/mb9oGq2FOl

[Chloé Loiseau @ChloeMLoiseau]

Congratulations @sgagneux1 🎉
The best supervisor and mentor. Grateful to have been part of your group and for your support, always!

[Swiss TPH @SwissTPH]

Congratulations to @sgagneux1 @SwissTPH for being promoted to a Full Professor of Infection Biology at @UniBasel🥳

Gagneux's focus is on #tuberculosis research, specializing in ecological & evolutionary aspects of this disease, particularly in the area of antibiotic resistance.

[Eric Topol @EricTopol]

The 🦠 continues to evolve, gets more fit, but has yet to outsmart the vaccines that humans made to block it. If only more humans could outsmart the virus by getting vaccinated. And block its capacity to evolve further.

[Conor Meehan @con_meehan]

PZA resistance confers a transmission fitness cost in MDR-TB!
Fantastic and meticulous work from the team including @DeniseKuehnert @gen_uv @sgagneux1 @TanjaStadler_CH and of course Julija leading us all.

https://t.co/yEGcYcns29

[Nature Medicine @NatureMedicine]

Understanding the role of prisons as ecological drivers of highly transmissible, multidrug-resistant Mycobacterium tuberculosis strains.

https://t.co/ukMMkSpgWC @GygSeb @ChloeMLoiseau @sgagneux1 #tuberculosis #genomics #epidemiology