In science for the ‘That’s funny...’ moments. Continuing the fascinating single cell path I started at the @sangerinstitute then @cnag_eu and now @AstraZeneca
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If you are not convinced, yet 😉, of how amazing induced pluripotent stem cells are, have a look at our latest work on human iPSC differentiation to myeloid cells now out in @NatureComms. @sangerinstitute@OpenTargets#singlecell#HumanCellAtlas https://t.co/piAx3vUQT9
Please check out or new paper describing a novel relationship between DNMT3A and telomeres. It truly was a team effort !
Even better when your former @Goodell_Lab baymate @TheKingLab publishes in @CellStemCell in the same issue!
I’m happy to share that our scCellFie manuscript is finally on bioRxiv — a project that was an amazing opportunity to return to my roots in metabolism!
We infer metabolic activity from single-cell & spatial transcriptomics 🧬
Read the pre-print here👇
📄 https://t.co/u1Al0Ot3Wo
How do genetic perturbations change cells? How are these effects shaped by cell type and dosage? How do we best extract insight from modern massive perturbation atlases? Im pleased to share a new preprint where we develop a suite of statistical approaches to these Qs (link below)
CellPhoneDB v5 is officially published!
https://t.co/gsGRTokngA
Very happy to have played a small role in it by developing some tools to help visualise the complex cell-cell interaction data!
📈💉 Since @Gavi’s inception in 2000, they have helped immunise more than 1.1 BILLION children around the world, averting >18.8 MILLION deaths.
💵🌎We call on donors to invest vital funding to build on this progress.
#ForOurFuture #VaccinesWork #HumanlyPossible #GlobalHealth
https://t.co/p2ffsKRdJq
𝐟𝐥𝐞𝐱𝐲𝐧𝐞𝐬𝐢𝐬, our new deep learning-based data integration tool for multi-omics.
1000s of deep learning workflows are available.
Paper: https://t.co/1yTHcPhPVm
Code: https://t.co/ObYfBGsucA
Benchmarks: https://t.co/puQlbsypwP
Tutorial/docs: https://t.co/hAPbdWvdtL
The mantra that spatial transcriptomics is about location, location, location is catchy, but what does it really mean? We have just posted https://t.co/oE9X6dHIko, work of Kayla Jackson et al., that describes the concordex method for identifying spatial homogeneous regions. 1/🧵
🏅 Today, Sergio Aguilar (@saguilarfer) successfully defended his #PhD Thesis
➡️Deciphering B lymphocyte dynamics in health and disease through the integrative analysis of multi-modal single-cell data
🧑🔬Thesis supervisors: Ivo Gut and @hoheyn
🙌Many congratulations!!!
#CNAG
📢#ScientificTalk: 07 November at @PCB_UB! (10am)
🧪Discover the latest immunogenomic #research and the key differences between primary and metastatic #tumors
🗣️@fran_mj88, Group Leader at @VHIO & Data Mining lead at @HartwigMedical
📍Fèlix Serratosa
ℹ️https://t.co/xzj5WukBIv
📢12th CNAG Symposium on Genome Research: State-of-the-art genomics
🧬Discover the latest innovations and amazing applications in #personalisedmedicine & #Biology
👉12 December 2023
🗣️12 international speakers
📍Barcelona, Spain
📩Register now! (free): https://t.co/X7dM8JpItH
The Tonsil Atlas 2.0 is now available through my first BioConductor package: HCATonsilData!
https://t.co/B0LvyuzZXe
In the revision , we have included 7 additional donors (adults), doubled the number of cells, and validated annotations. Here's how you can access all datasets👇