Collette LaVigne

Graduate student in the Mendell Lab at UT Southwestern

[Collette LaVigne @ColletteLavigne]

It's out! Check out our pre-print below!

[Joshua Mendell @Mendell_lab]

I am pleased to present our latest pre-print describing our identification of the long-sought triggers for target-directed microRNA degradation (TDMD) of miR-322 and miR-503, led by @ColletteLavigne and @Jaeil__Han. Read on for more info!👇 https://t.co/nXUh0y0Qsj

[Collette LaVigne @ColletteLavigne]

@GabyCanoH Congrats Gaby! Can't wait to read!

[Collette LaVigne @ColletteLavigne]

@ASolmonson @UTSWGreenCenter @UTSW_ObGyn Congrats!!

[Dr. Megan L Norris @Megan_L_Norris]

We had a really positive experience publishing this paper. Thanks to the reviewers and @GenesDev!

https://t.co/LulbUkAHdA

[Collette LaVigne @ColletteLavigne]

It's out! Congrats to all - such a great team effort!

[Genevieve Kendall, Ph.D. @KendallLabNCH]

Excited to see our work out @CellReports! We generated multiple models of fusion-driven infantile #rhabdomyosarcoma to understand conserved disease biology and identify therapeutic opportunities. Check it out! 👇 🧫🐟🐭 @NCHforDocs @OhioStateMed

https://t.co/bconkLJEWe

[Collette LaVigne @ColletteLavigne]

Looking for a GREAT mentor to work on pediatric sarcomas? You're in luck!

[Genevieve Kendall, Ph.D. @KendallLabNCH]

And we are now hiring for postdoctoral positions. If you are interested in joining our team please send me a cover letter and CV- we have a lot of exciting project opportunities!

[Collette LaVigne @ColletteLavigne]

@KendallLabNCH @NIH @theNCI @nationwidekids @OhioStateMed @OSUCCC_James Congratulations Genevieve and team!!

[Collette LaVigne @ColletteLavigne]

@dagan_segal @JCellBiol Congrats!! Can't wait to check out the live cell imaging data

[Collette LaVigne @ColletteLavigne]

@RJDLab @ASolmonson @CRI_UTSW @Nature Congrats @ASolmonson and @RJDLab! So exciting to see this work out!

[Collette LaVigne @ColletteLavigne]

@EVasilevaSci @eLife @amatrudalab Congratulations Elena!

[Genevieve Kendall, Ph.D. @KendallLabNCH]

New work from our group! ✍️ We generated a #zebrafish her3 CRISPR/Cas9 knockout to study the role of her3/HES3 in development and provide clues for its role in tumorigenesis.

https://t.co/2RqsATDkSQ

[Collette LaVigne @ColletteLavigne]

First paper from the @KendallLabNCH and my own first first-author!
We took a rare fusion protein identifed by clinical sequencing of pediatric #rhabdomyosarcoma and developed zebrafish and mouse models to confirm the oncogenic potential and identify possible therapeutic targets

[Genevieve Kendall, Ph.D. @KendallLabNCH]

So excited our paper is up on bioRxiv focused on novel models of fusion-driven infantile #rhabdomyosarcoma.

https://t.co/cKPovMyCrn

[Collette LaVigne @ColletteLavigne]

@notinthemoud @Mendell_lab @Jaeil__Han @Megan_L_Norris Congrats again, Dr. Elguindy! We will miss you in lab but wish you the best!

[Collette LaVigne @ColletteLavigne]

@RJDLab @CRI_UTSW @utswpediatrics Congrats Pany!

[Collette LaVigne @ColletteLavigne]

I got to work with Jae on this exciting project as a rotation student and joined the lab as soon as I could after! It's a beautiful story about the molecular machinery that mediates target directed microRNA decay (TDMD)

[Joshua Mendell @Mendell_lab]

I am excited to present this work led by the very talented postdoc Jaeil Han in which we identify a ubiquitin ligase complex that promotes the degradation of microRNAs engaged with highly complementary targets. A detailed thread follows.
https://t.co/XOzwulbSK6

[Collette LaVigne @ColletteLavigne]

@RJDLab @theNAMedicine Congratulations!

[Collette LaVigne @ColletteLavigne]

@KendallLabNCH Congrats! I'm pumped to see all your success in year TWO!

[The Nobel Prize @NobelPrize]

BREAKING NEWS:
The 2020 #NobelPrize in Chemistry has been awarded to Emmanuelle Charpentier and Jennifer A. Doudna “for the development of a method for genome editing.”

[Collette LaVigne @ColletteLavigne]

Very cool new tool for lineage tracing!

[Sarah Bowling @SarahBowling15]

Out now in @CellCellPress! Details of our new CRISPR-barcoded mouse model for inducible in vivo lineage tracing + scRNAseq, and how we used it to investigate blood stem cell behaviour in development & after myeloblation. https://t.co/LszmNX6h0V

[Joshua Mendell @Mendell_lab]

Pleased to present Jong-Sun Lee's work showing that antisense knockdown causes transcription termination. These reagents cannot be used in isolation to establish an RNA-mediated function for noncoding RNA loci!
https://t.co/UFYiYbt7sp