Cornell Center for Enervating NeuroImmune Disease

Collaborative #research center based @Cornell directed by @DrMaureenHanson encompassing a variety of projects on #MECFS. Visit our website below for more info.

[Cornell Center for Enervating NeuroImmune Disease @CornellMECFS]

Graphical abstract by Arnaud Germain, PhD.

[Cornell Center for Enervating NeuroImmune Disease @CornellMECFS]

Center researchers performed longitudinal plasma proteomics (SomaScan7K ) in 79 #MECFS vs 53 controls around two maximal CPETs. Findings: Persistent immune & metabolic dysregulation in recovery, linked to PEM. Learn more on our website.

https://t.co/KHdCXhywcX

#PEM #Research

[Cornell Center for Enervating NeuroImmune Disease @CornellMECFS]

This work by Germain et al. has been featured on @Medscape.
https://t.co/GEUYykfcaB

[Cornell Center for Enervating NeuroImmune Disease @CornellMECFS]

Proud to share this spotlight on @DrMaureenHanson—ME/CFS overview, current science, and a call to fund clinical trials. Video below. #MECFS

[#NotJustFatigue @njfatigue]

Thank you to everyone who came out to our livestream event! During it, we premiered a video on @DrMaureenHanson that we’re sharing here as well

[Cornell Center for Enervating NeuroImmune Disease @CornellMECFS]

Proud of our Center team! Kudos to Center member @GardellaAnnie from @IwijnDeVlaminck's lab for this excellent work 🤝🧬Exciting to see our cross-lab collaboration in action. More details 🔗https://t.co/IG8KVpun8S

[Annie Gardella @GardellaAnnie]

Our work using cell-free RNA as a minimally invasive bioanalyte to investigate circulating biomarkers and the pathobiology of ME/CFS is out today in @PNASNews!

Led by @IwijnDeVlaminck, @DrMaureenHanson, and @CornellMECFS

#cfRNA #MECFS #PNAS
https://t.co/J9R6kEZAIF

[Maureen Hanson @DrMaureenHanson]

Today David Iu, a PhD student in Andrew Grimson's lab at the Cornell ME/CFS Center, passed his thesis exam. As well as co-authoring several published papers already, David will be completing another manuscript on immune cells in ME.

[Cornell Center for Enervating NeuroImmune Disease @CornellMECFS]

Analysis shows impaired energy metabolism, upregulated complement system, and dysregulated protein folding. Proteomic changes were associated with ME/CFS patients’ post-exertional malaise, unrefreshing sleep, and functional capacity.

[Cornell Center for Enervating NeuroImmune Disease @CornellMECFS]

🔬 NEW from @CornellMECFS: Study reveals protein changes in #MECFS using blood-derived extracellular vesicles. First analysis in male patients shows altered EV cargo dynamics post-exercise.

🔓 Read: https://t.co/XSKewWsowr
📊 Data: https://t.co/hgiV40yyCJ

[Cornell Center for Enervating NeuroImmune Disease @CornellMECFS]

🔍 New study from Center examines role of autoantibodies in #MECFS. 🧪 Using advanced screening of 7,500+ antibody-antigen interactions in 172 participants, researchers found no significant differences between patients & controls. 📄 Read more: https://t.co/3QtepG0i3V

[Cornell Center for Enervating NeuroImmune Disease @CornellMECFS]

We're expanding our social media presence to other social platforms! 🌟

Head over to our Facebook page for more information.

https://t.co/ORmQbYKAlN
#MECFS #MEResearch #Cornell

[Cornell Center for Enervating NeuroImmune Disease @CornellMECFS]

📢 New insights into #MECFS: Research from our Center reveals how T cells become exhausted in ME/CFS patients. 🧬 Learn more about the study and its implications in the @CornellChronicle article: https://t.co/rlaVffhxxI #TCells #Immunology

[Cornell Center for Enervating NeuroImmune Disease @CornellMECFS]

Check out our website's news feed (link below) for a post regarding the recent #MECFS #CPET paper by Betsy Keller et al. out in the Journal of Translational Medicine. 👉https://t.co/D6rM9jgGz2

[Maureen Hanson @DrMaureenHanson]

It was great to see former graduate student Jessica Maya at the InvestinME meeting. She is continuing ME/CFS research as a postdoctoral fellow at CDC in Atlanta. She participated in the Young EMERG meeting.

[Cornell Center for Enervating NeuroImmune Disease @CornellMECFS]

The NIH NINDS ME/CFS Research Roadmap report has been released. Here is a post outlining the release: https://t.co/XtAGru3fBF

Interested in the full report? Check it out here: https://t.co/E97HCTn4l3

[Cornell Center for Enervating NeuroImmune Disease @CornellMECFS]

If you have not seen, Center Director @DrMaureenHanson and @oslersweb have an op-ed out in The Hill. Please share to promote funding for #MECFS.

[Maureen Hanson @DrMaureenHanson]

I hope our op-ed in The Hill will raise awareness of the need for substantial funding for pre-pandemic ME/CFS. Treatments are needed for all infection-associated chronic conditions. https://t.co/26uLgcXRho

[Cornell Center for Enervating NeuroImmune Disease @CornellMECFS]

Until the DOI link is active, please use: https://t.co/g6Z8GUqqbx

[Cornell Center for Enervating NeuroImmune Disease @CornellMECFS]

The Center has a new publication out on single-cell transcriptomics in #MECFS. Congrats to the Grenier and Grimson labs and everyone that contributed! The paper is open access in Cell Reports Medicine. https://t.co/hPAlyU5qtP

[Cornell Center for Enervating NeuroImmune Disease @CornellMECFS]

Check out this recent #MECFS publication from our Center on leveraging multiple datasets to distinguish people with MECFS from controls.

[Maureen Hanson @DrMaureenHanson]

Results of a collaboration between the Cornell and Columbia NIH ME/CFS Centers have now been published in JTM. Analysis of plasma proteins and extracellular vesicle cytokines distinguishes ME/CFS from healthy at 86% accuracy. https://t.co/fbt34drk0P

[Maureen Hanson @DrMaureenHanson]

On International #MECFS day, the drawing below by Cornell researcher Jessica Maya is dedicated to all sufferers. The Cornell Center for Enervating Neuroimmune Disease will continue research aimed at understanding the disease so treatments can be developed.

[Cornell Center for Enervating NeuroImmune Disease @CornellMECFS]

The Center is excited and grateful to have received a renewal of our collaborative research center. The 5-year U54 award funds a multidisciplinary team working to uncover the biological basis of #MECFS. Check out our website for more information. https://t.co/D6rM9jg8Ju

[Cornell Chronicle @CornellNews]

A @Cornell multidisciplinary research center that studies chronic fatigue syndrome has received a $9.5M grant from @NIH – funding that will enable experts to continue work on the mysterious and debilitating condition. @NIAIDFunding @KrishnaWriter https://t.co/rVLoHCp0cD