Costa Lab

Biochemists & cryo-EM scientists studying chromosome replication @TheCrick

[Costa Lab @CostaLabCrick]

I have received a Wellcome Discovery Award to study the initiation of eukaryotic DNA replication. 8 years of funding at the Crick Institute.

Looking for a postdoc in molecular mechanism, cryo-EM and in situ structure?

Contact me now! 3 postdoc positions advertised soon.

[Costa Lab @CostaLabCrick]

@EAriasPalomo Thank you, Ernesto!

[Costa Lab @CostaLabCrick]

How does ATP hydrolysis by MCM enable replicative helicase loading onto DNA?

Find the answer in our latest article
https://t.co/OKrGwsCNr8

Congratulations to Agata Butryn, who spearheaded the entire project, Contributions from @GreiweJulia in the early days.

🎉❄️🔬🧬

[Costa Lab @CostaLabCrick]

@lab_reyes Thank you, Rodrigo!

[Costa Lab @CostaLabCrick]

I have received a Wellcome Discovery Award to study the initiation of eukaryotic DNA replication. 8 years of funding at the Crick Institute.

Looking for a postdoc in molecular mechanism, cryo-EM and in situ structure?

Contact me now! 3 postdoc positions advertised soon.

[Costa Lab @CostaLabCrick]

https://t.co/IWgbEFAPh5

[Costa Lab @CostaLabCrick]

@Jacob_Lewis90 @MolHorizons @LMSpenkelink Fantastic news @Jacob_Lewis90 and @LMSpenkelink ! Well done!

[Costa Lab @CostaLabCrick]

@Jacob_Lewis90 Thank you, Jacob!

[Costa Lab @CostaLabCrick]

Our article "MCM double hexamer loading visualized with human proteins" published in Nature today! ❄️🔬🧬🎉🥳

Great collaboration with John Diffley's lab. Congratulations to Florian Weissmann, Julia Greiwe and all other authors! https://t.co/D13VcIXABT

[Costa Lab @CostaLabCrick]

@TCR_Miller Congratulations to you, Tom, for conducting the key experiment that initiated the structural project!

[Costa Lab @CostaLabCrick]

@EAriasPalomo Thank you, Ernesto!

[Bleichert Lab @BleichertLab]

Our study on how the human MCM2-7 helicase is loaded onto replication origins 🧬 is now online @Nature! 🎉

Our findings reveal that unlike in yeast, human MCM loading does not require ORC6 and can occur through multiple pathways.

Read more here: https://t.co/bPT5Y4uPkR

[Anja Groth 🇺🇦 @groth_anja]

Great kickoff for the EMBO EMBL Replication symposium with amazing structural and functional insights into initiation, elongation and histone recycling 🧬♻️ @TyeBik @CostaLabCrick @BleichertLab @Speck_Lab Chistol @Lopes_Lab Méchali @YardimciLab 🙌
#EESReplication @EMBLEvents

[Costa Lab @CostaLabCrick]

@MRC_LMB @SjorsScheres @lapassmore Congratulations @lapassmore !

[Costa Lab @CostaLabCrick]

@LlorcaLab @sernarina @LudersLab @IRBBarcelona Very cool, Oscar!

[The Nogales Lab @NogalesLab]

Looking forward to this!

[EMBL Events @EMBLEvents]

⏰ Deadline approaching for #EESReplication ⏰

Submit your abstract by 13 August and find out about the latest breakthroughs in DNA replication 🧪🧬

📅 5 – 8 November
📍 EMBL Heidelberg and Virtual
➡️ https://t.co/LN2ddsJprt

[Costa Lab @CostaLabCrick]

@FMattiroli @Jacob_Lewis90 Thank you, Francesca! See you (and Jacob who's also reading this) soon in Cambridge!

[Costa Lab @CostaLabCrick]

@Jacob_Lewis90 Thank you, Jacob!

[Costa Lab @CostaLabCrick]

@robertobellell1 @TheCrick @EMBO Thank you, Roberto!

[Costa Lab @CostaLabCrick]

@KellyTHD_Nguyen @TheCrick @EMBO Thank you, Kelly!