Our study on how the human MCM2-7 helicase is loaded onto replication origins 🧬 is now online @Nature! 🎉
Our findings reveal that unlike in yeast, human MCM loading does not require ORC6 and can occur through multiple pathways.
Read more here: https://t.co/bPT5Y4uPkR
Our article "MCM double hexamer loading visualized with human proteins" published in Nature today! ❄️🔬🧬🎉🥳
Great collaboration with John Diffley's lab. Congratulations to Florian Weissmann, Julia Greiwe and all other authors! https://t.co/D13VcIXABT
We're excited to announce a tenure-track or tenured faculty position in Cellular Biophysics and Structural Biology! We are especially excited to hear from candidates who develop in situ approaches in structural cell biology. Join us in MB&B!
Apply now at https://t.co/it80VM0UyI
Congrats to grad students Ran Yang and Olivia Hunker for giving a wonderful talk at the MB&B retreat and also for winning poster awards!
The lab had a great time socializing with our colleagues and hearing about all the amazing work being done in the department.
Our high-resolution (2.2 Å) in situ structural work reveals details of translational landscape, with various cofactors and antitumor drug/inhibitor, all directly within human cells!
https://t.co/ScWOAQRjTw
Here is a recent posting for a Lecturer position with the Department of Molecular Biophysics and Biochemistry (MB&B) at #Yale University. Please consider joining our research and educational community @YaleMBB and contributing to these important missions! https://t.co/xo2uJUn6zp
New preprint with the latest work from our lab! Grad students Ran Yang and @okhay97 demonstrate reconstitution of human origin licensing using purified proteins.
High-res In-situ Structures of Mammalian Respiratory Supercomplexes in Reaction within Native Mitochondria https://t.co/YZZ2njfWd4
Check out my lab's first work on membrane proteins!
Yes, we knew nothing about detergent😜, so we directly imaged proteins within native membrane!
Thank you to everyone who came to our Thanksgiving themed science social on Friday. We had a wonderful time sharing food, drinks, and conversation with you all! Also shout-out to our co-hosts in @LabPaulsen for doing a fantastic job!
Yale MB&B is seeking a Lecturer to contribute to our educational mission. Please consider joining our scientific community and using your skills for teaching biochemistry. You will work with fantastic colleagues and enthusiastic students! @YaleMBB https://t.co/rBjAybI3KP
Our GSMI panel “Grad Student Panel on: PhD admissions in the Biological Sciences” will be NEXT WEEK on10/23 at 2:30pm EST
Learn how to craft an effective PhD application and what interviewing was like from our grad student panelist! #CLGSMI
Register ➡️ https://t.co/Mvu6MM0V2t
The lab had a great time at the @YaleMBB retreat last week. Congrats to Olivia for delivering a fantastic talk and to Ran for winning the poster award!
We folded over 40,000 pairs of ~300 human #genomemaintenance proteins with #AlphaFold multimer. Check out all the structures and the analysis at https://t.co/n1Yy3hoFLl! #cshreplication