CSHL Mass Spec Core

[CSHL Mass Spec Core @CshlMassSpec]

Contributions: David, Kavita and Maria contributed design ideas, useful skepticism, and a lot of cheering from the shore. Acknowledgments. We thank Facilities for the materials, the help, and most of all for not competing this year.

[CSHL Mass Spec Core @CshlMassSpec]

With Darcy and Fra in the engine room, and Paolo leisurely holding the helm, the Peak Paddlers won the CSHL raft race!

[CSHL Mass Spec Core @CshlMassSpec]

Fashionably late, but congratulations to our friend Mohita for pushing her paper over the line. This time we got to measure lactylation: another rare PTM checked of the bucket list. https://t.co/xAg6DHbWcF

[CSHL Mass Spec Core @CshlMassSpec]

A new Research Tech joined the MS Shared Resource: welcome David Boone! David comes to CSHL after shining as an undergrad synthetic chemist at Hofstra. Now he will look at small (biological) molecules through ion lenses and orbitrap detectors.

[Paolo Cifani @paolocifani]

BUT DIA IS MORE SENSITIVE. There are a lot of application, from PTM analyses to TMT experiments, that still require DDA. At @CshlMassSpec we use HDR-DDA when we need good interpretable MS2, and go DIA when numbers matter.

[CSHL Mass Spec Core @CshlMassSpec]

New paper 💡The molecular basis of Human FN3K mediated phosphorylation of glycated substrates | Nature Communications https://t.co/G08svq9zLh

[CSHL Mass Spec Core @CshlMassSpec]

Happy Holidays from the Cifani Lab!

[Paolo Cifani @paolocifani]

@manojit_ms 's magnum opus is out there! This is an incredibly rich paper (could have been three papers, really). Big congrats to Manojit and the @trotmanlab! https://t.co/BtJcrBWFvY

[CSHL Mass Spec Core @CshlMassSpec]

Cifani Lab celebrated the end of summer with a bbq on the CSHL beach!

[CSHL Mass Spec Core @CshlMassSpec]

@KentsisResearch @paolocifani It goes without saying that the beers on the table were from my basement. Choice of amber ale and triple malt stout (which made Jenga way more challenging)

[CSHL Mass Spec Core @CshlMassSpec]

New paper from the Cifani Lab 💡 https://t.co/k7ByioQh8y

[CSHL Mass Spec Core @CshlMassSpec]

New paper alert 💡SRSF1 interactome determined by proximity labeling reveals direct interaction with spliceosomal RNA helicase DDX23 - PubMed https://t.co/QEhRHtIyxp

[CSHL Mass Spec Core @CshlMassSpec]

We welcome Peter Verhaert at CSHL. One of the pioneers of peptide MS, he's now pushing the boundaries of spatially resolved measurements of proteins and peptides, and he's sharing this with us.

[CSHL Mass Spec Core @CshlMassSpec]

🔬Looking to join a fun group of mass spec enthusiasts? The #CifaniLab is looking for post-docs! Apply here:
https://t.co/zM2N7niFAX

[CSHL Mass Spec Core @CshlMassSpec]

New paper alert 💡Two related families of metal transferases, ZNG1 and ZNG2, are involved in acclimation to poor Zn nutrition in Arabidopsis - PubMed https://t.co/DyY7UKeyHg

[CSHL Mass Spec Core @CshlMassSpec]

Happy Holidays from the CSHL Mass Spec Core!

[Paolo Cifani @paolocifani]

Are you a passionate #LC-MS geek? Eager to take on important technical and biological questions? Wanna work in place with a private beach and beach volleyball court? Join us!!! https://t.co/xS4cDWV9rL

[CSHL Mass Spec Core @CshlMassSpec]

Little pilot at @CSHL MS core: we train users to prep their samples on their own and we provide tested equipment, MS-grade reagents and consumables. Judging from the smile of coach Francesca, so far it was a success! (let's post this before seeing the chromatograms...).

[CSHL Mass Spec Core @CshlMassSpec]

#proteomics twitterverse! The MS core facility at Cold Spring Harbor Labs is recruiting techs, lab manager, proteomic science and almost any level of geeks that like science, LC and MS. Contact us to know more about this position! #proteomicjob #massspec https://t.co/VAHaeePCgi

[Paolo Cifani @paolocifani]

Today I learned from @OdedRechavi how acquired traits can be inherited (one of the best scientific talks I ever attended). Mechanism proposed is based on RNA so now I'm here thinking of possible protein-based ways to transmit information across cell generations (beside prions)