Real-🌎 data in Veterans with fXaI-related ICH treated w/ andexanet alfa (AA; n=129) or 4F-PCC ( n=221)
🔷Propensity matched (n=123 matches)
🔷No difference in 90-day mortality
🔷⬆️30-day thrombotic events w/ AA (11.4 % vs. 2.4 %, p < 0.01)
Free 👉https://t.co/jzeOpP7jlC
@PCC_PharmD @GilbertPharmD @PharmD_intheED@PharmacyToDose@AJWPharm This is interesting, they have the data on when the TEs occurred, but they don't share when they started VTE ppx? If this clip is accurate, most TEs occurred in first 5 days. This trial has more questions than answers.
https://t.co/0CStlXgUZG
@ShadiYaghi2@Ash_Shoamanesh@DavidSeiffge AA for surgical cases? Such a short effect time, not to mention ANNEXA - S trial getting shut down.
https://t.co/I9rY0Q5WYf
Also, can run into sticky situations with AA and heparinizing the patient if needed.
https://t.co/GmY5KxQG04
@ChildrenNeedUs_@notcapnamerica You can prescribe it to give intranasally to abate seizures. However, you'd think a neurology specialist would prescribe it.
@mganio_ASHP @erikaedwardsnbc@marinakopf When most med spas have cash only payment, it allows them to have a nice contract with the 503b compounding pharmacies. But yes, some regulation needs to be implemented.