Dominik Lindenhofer

[Nature Methods @naturemethods]

SDR-seq is a droplet-based single-cell DNA-RNA sequencing platform for studying gene expression profiles linked to both noncoding and coding variants.
@DLindenhofer @LarsMSteinmetz @embl

https://t.co/Jj6TpEtxlK

[Dominik Lindenhofer @DLindenhofer]

We are excited to share that our paper on SDR-seq, a combined single-cell DNA-RNA sequencing method, has been accepted and published in @naturemethods! 🎉
Watch co-author Julia Bauman’s video on how SDR-seq links coding & non-coding variants to gene expression.

[Julia Bauman @JuliaBauman2]

What good is a science communication channel if you don't get to talk about your own papers on it occasionally, right?😊

We developed a method to simultaneously sequence single-cell DNA and RNA targets, enabling association of genomic variants (including non-coding!) with gene expression changes.

Out today in @naturemethods, from @LarsMSteinmetz lab led by @DLindenhofer! Link below⬇️

[Lars Steinmetz @LarsMSteinmetz]

We are excited to share that our paper (D. Lindenhofer et al.) on SDR-seq, a combined single-cell DNA-RNA sequencing method, has been published in @naturemethods! 🎉 
Watch co-author Julia Bauman’s video on how SDR-seq links coding & non-coding variants to gene expression.

[Dominik Lindenhofer @DLindenhofer]

Very pleased to share our recent preprint for a targeted scDNA-scRNA-seq method. Thx a lot to everyone who contributed!

https://t.co/sSBn3R6saz

[Lars Steinmetz @LarsMSteinmetz]

We are very happy to share our preprint (D. Lindenhofer et al.) of a high-throughput targeted scDNA-scRNA-seq (SDR-seq) method. Impactful for any application with a need to associate coding and non-coding variants to gene expression in tissue samples and cell culture systems.

[The Knoblich Lab @Knoblich_lab]

📢 We’re excited to share another story published this week in @NatureCellBio! An effort led by @DLindenhofer, Simon Haendeler, @christopher_esk & @jamielittleboy1.

Cerebral organoids display dynamic clonal growth and tunable tissue replenishment
(https://t.co/xJNLOJspxN)

🧵1/9

[Lars Steinmetz @LarsMSteinmetz]

Excited to share our latest work in @ScienceMagazine!  The talented #Synbio duo @scalefreegan & Amanda Hughes explored the transcriptional consequences resulting from scrambling pieces of the genome & putting them back together in a random order...

Excellent thread by Aaron👇

[Lars Steinmetz @LarsMSteinmetz]

In an exciting collab with @embl scientists & @BDBiosciences we put image-enabled cell sorting to the test, unlocking countless opportunities for scientific exploration by isolating single cells with complex phenotypes. Out now in @ScienceMagazine w great🧵 by @SchraivogelS

[Joschka Hey @HeyJosch]

I'm excited to present our work on the relationship of the muco-obstructive lung environment and airway macrophages, published today @NatureComms😍.
It's the result of a wonderful collaboration between the Plass @DKFZ and Mall Lab @ChariteBerlin.
👉https://t.co/HpqILcMb4N👈

1/11