Daniel Kneller

Structural biologist using #neutrons to study viral drug targets at the atomic level @ORNL. Now advancing synthetic mRNA technology @NEBiolabs.

[Daniel Kneller @DanielKneller]

We hybridized Hepatitis C drugs into effective new #SARSCoV2 main protease inhibitors.

Neutron + X-ray structures, binding thermodynamics, and antiviral assays are out now @NatureComms

Great collaboration between @ORNL @ILLGrenoble @NIH and @uthsc
https://t.co/IWJi3Y0vrz

[National Academy of Sciences @theNASciences]

The winner of the 2023 NAS Award in Molecular Biology is Jason S. McLellan of @TexasScience! He is being honored for pioneering work in the molecular and structural biology of viral surface proteins. Learn more: https://t.co/S3djB0FGtp #NASaward #MolecularBiology

[Daniel Kneller @DanielKneller]

@Goga2025 The Midtown skyline from that spot is one of the best in all Atlanta. Great picture!

[Daniel Kneller @DanielKneller]

New visualization tools can introduce a fresh perspective to enable new hypotheses.

[Nanome @nanome_inc]

New Case study alert❗ It's the story of how @KovalevskyAY and @DanielKneller from @ORNL jumped into #VirtualReality to optimize leads coming from virtual screenings. They found new substituents that made a more potent inhibitor against #MPro. Full story ➡️https://t.co/lxIPOwtnga

[Daniel Kneller @DanielKneller]

@DanielKeedy @biorxivpreprint Fascinating and important work!

[Daniel Kneller @DanielKneller]

@AustinClyde13 Congratulations Austin!

[Alex Palazzo @ribonucleicacid]

Dr. Yasuhiro Furuichi, the discoverer of the cap structure of mRNA, passed away at the age of 81. (Not yet reported in English media, but apparently in Japanese media - see translated page below.)

[UBuffalo Hauptman-Woodward Research Institute @UB_HWI]

Dr. Sarah EJ Bowman and Dr. Miranda L Lynch have received a new $1.57M grant from the National Institutes of Health to support their research on detecting and handling small crystals for cutting-edge structural biology.

[Daniel Kneller @DanielKneller]

@AustinClyde13 I'm curious if this manifests differently for you in writing code compared to text

[Daniel Kneller @DanielKneller]

@miches_niche @denbizjournal How awesome to be recognized, well deserved Michelle!

[Daniel Kneller @DanielKneller]

Temperature is important factor for understanding ligand binding and protein dynamics.

[C&EN (Chemical & Engineering News) @cenmag]

For drug design, scientists determine how small molecule fragments bind to their targets using X-ray diffraction at cryogenic temperatures. But new research presented at #ACSFall2022 shows that these cryogenic screens may yield an incomplete picture. https://t.co/3WWJMh23tV

[Daniel Keedy @DanielKeedy]

Very pleased to report that our multitemperature Mpro paper spearheaded by @DrAliEbrahim @blake_riley is officially out in @IUCrJ !

[Daniel Kneller @DanielKneller]

Don't miss our #acamtg2022 session, structural science of infectious disease at 2 PM today!

[Chi-Min Ho @mimi1inh]

T-minus 1.5hrs until #acamtg2022 Session 2.2.3: Structural Science of Infectious Disease today at 2PM!!

Looking forward to a fantastic lineup of viral, bacterial and parasitic structures, featuring @reeselab1 @BhabhaEkiertLab @kwhuynh and our keynote David Veesler @veeslerlab!!!

[Chi-Min Ho @mimi1inh]

T-minus 1.5hrs until #acamtg2022 Session 2.2.3: Structural Science of Infectious Disease today at 2PM!!

Looking forward to a fantastic lineup of viral, bacterial and parasitic structures, featuring @reeselab1 @BhabhaEkiertLab @kwhuynh and our keynote David Veesler @veeslerlab!!!

[Daniel Kneller @DanielKneller]

@NickBastianAZ Thank you! It feels good to do my alma mater proud and show that SLACs are great places to nurture curious young minds.

[Daniel Kneller @DanielKneller]

Greatly appreciative of @bradleyu, specifically Naomi Stover and @mindymaris, helping me start off my science journey!

The Right Expert at the Right Time | Bradley magazine | Bradley University https://t.co/iyfDTC8ons

[Daniel Kneller @DanielKneller]

@KazzTheMiro @BradleyUn Haha! The editor of Bradley Magazine must have been a tax collector in their past life because they never fail to find me.

[Oak Ridge Lab @ORNL]

Meet Frontier — the world's first #exascale computer!

At 1.1 exaflops, Frontier is also the world's fastest #supercomputer and can solve more than a quintillion calculations per second. 🤯

#DiscoverFrontier ➡️ https://t.co/Yk0HA7PzmK

[Daniel Kneller @DanielKneller]

Rock on!
AC/DC, the new $52 Million Antiviral Drug Discovery Center Established by Researchers at Emory University and Georgia State University

https://t.co/A9pMZfSGMe

[Neutron Sciences @ORNLNeutrons]

After more than two years of studying the #COVID19 virus, neutron scientists at @ORNL and @ILLGrenoble are designing and testing #antivirals that block the virus’s ability to reproduce. https://t.co/T0iWkfdPA0

#NatLabsInTheFight @NatureComms