Dylan Holst

Discovery High Throughput Chemistry @gsk | PhD '23 @wickensgroup

[J. Am. Chem. Soc. @J_A_C_S]

📽️ In this new video, the @WickensGroup discuss their recently published article "Regiospecific Alkene Aminofunctionalization via an Electrogenerated Dielectrophile". @ZachWickens @De_holst 

Watch the video ➡️ https://t.co/wVMvr8ltNN
Read the article ➡️ https://t.co/6Sd8K9RQTm

[Wickens Group @WickensGroup]

Check out our new hydrocarboxylation story! We found our previous system was ineffective for challenging unactivated alkenes but, using a mechanistically-guided approach, we develop a new catalytic system that unlocks this substrate class. Out in @J_A_C_S https://t.co/dQEtpOfNwp

[Grace Lutovsky @grace_lutovsky]

So happy to share that our work using iron(III) salts and visible light to enable cross-nucleophile coupling reactions is out now! Working with Sam, @TehshikYoon, and our collaborators at Pfizer, Mark and @BagPhos, has been an absolute pleasure.
https://t.co/xiJwGUgXzB

[Dylan Holst @De_holst]

Check out my last major project from grad school!! Amazing to work with Céline and superstar undergrad Casey, who had major contributions early in the project. My favorite part was discovering that proton balance is vital for controlling the reactivity of alkenyl sulfonium salts!

[Wickens Group @WickensGroup]

Check out our new platform for alkene aminofunctionalization! We found that dicationic adducts of alkenes and thianthrene undergo selective single substitution by phthalimide to provide a sulfonium salt that can be substituted with various nucleophiles. https://t.co/chJep7PmOU

[Jacksonville Jaguars @Jaguars]

The time has come 😔 As we say goodbye for now to our Steezy Trev profile picture, we want to thank fans with this exclusive t-shirt. RT and like for your chance to win one!

#DUUUVAThe time has come 😔 As we say goodbye for now to our Steezy Trev profile picture, we want to thank fans with this exclusive t-shirt. RT and like for your chance to win one!

#DUUUVAL

[Wickens Group @WickensGroup]

Time to make more triangles! We introduce our new diastereoselective cyclopropanation protocol using the electrochemical dication pool strategy. Check out all the cool cyclopropanes you can now access at https://t.co/1JOHITedmL!

[Wickens Group @WickensGroup]

@OliverPWill and @AlyahChmiel introduce an alcohol deletion protocol using formate and light! But this time, potent reductants weren’t enough. We had to work out how to accelerate fragmentation after reduction. Spoiler alert: acidic promoters were key! https://t.co/orsQfmk51y

[Sara Alektiar @SaraAlektiar]

Excited to share our latest hydrocarboxylation project! Check it out ⬇️

[Wickens Group @WickensGroup]

Heading to ACS Chicago? Come check out the Wickens group!

[Weix Group @weixgroup]

Ring, ring, ring, ring, ring, ring, ring, banana bond! Our work by Daniel and Ben, in collaboration with @JanssenGlobal on accessing arylated strained rings is now accepted in @angew_chem! https://t.co/AqGOW7cG0Q

[Wickens Group @WickensGroup]

Week of many accomplishments for the Wickens group! Congrats @thechestersang for passing his second year exam, @minjik1997 for passing her third year research proposal, and @alyahchmiel for giving a great departmental supergroup presentation!

[Tehshik Yoon @TehshikYoon]

Our second paper of 2022, published on Twosday 2/22/2022, is about double stereodifferentiation in dual catalytic [2+2] photocycloadditions, with two great collaborators (@Toste_Group and @christine_m_le) https://t.co/0bYM419U3Q

[Wickens Group @WickensGroup]

In honor of the #WomenInScience day, we wanted to highlight the scientific contributions of the women in the group with a short thread... Every one of our papers to date has had a woman as either first or co-first author!

[Wickens Group @WickensGroup]

what better way to welcome our new postdoc and first years to Wisconsin winters than a walk on the frozen lake!

[Grace Lutovsky @grace_lutovsky]

I am happy to share our most recent work harnessing the photoactive properties of Cu(II) is out now in @NatureChemistry! https://t.co/gX2SF7oPHb

[Stahl Lab @Stahl_Lab]

Want to replace a C–H bond with an oxidatively sensitive coupling partner? Marco Lopez/Josh Buss developed a C–H chlorination/substitution method to achieve this goal. @UWMadisonChem https://t.co/sk9oaxUsXW

[Wickens Group @WickensGroup]

You’ve seen aziridination using our electrochemical dication pool strategy. Now check out this unexpected Z-selective allylic amination process that couples amines and alkenes! Congrats @dj_wang_ and Karina! https://t.co/qIWbI63EPu

[Weix Group @weixgroup]

Kai and Nathan's general synthesis of biheteroaryls from heteroaryl halides and heteroaryl triflates is now online at @J_A_C_S ! Check it out if you like long walks on the beach, biheteroaryl compounds, and multimetallic catalysis. https://t.co/gjtn24sLnO

[J. Am. Chem. Soc. @J_A_C_S]

Electrochemical Synthesis of Allylic Amines from Terminal Alkenes and Secondary Amines @Amines #Electrochemistry @WickensGroup @ZachWickens https://t.co/Jto6d6pmMi

[J. Am. Chem. Soc. @J_A_C_S]

DNA-Scaffolded Synergistic Catalysis @JeffChem @UWMadisonChem @UWMadScience @uwsmph #DNA #Catalysis https://t.co/VQ5VQJGg4q