Mitochondrial damage, what does that actually mean and why can’t mitochondria just fix themselves?
Mitochondria are like little batteries inside your cells. They power everything from your muscles and nerves to your brain and heart. Fluoroquinolone class of antibiotics can damage mitochondrial DNA because these antibiotics are designed to attack bacteria. Mitochondria actually evolved from bacterial ancestors, so the drugs sometimes confuse the two. That’s where the damage begins.
When that DNA is damaged, your body struggles to make energy. That’s why symptoms or adverse effects can be so widespread. But here’s the hopeful part: if enough healthy mitochondria are still functioning, your body can slowly replace the damaged ones. This is key! It takes time. Recovery might be slow or faster depending on how much damage was done, your genetics, and how well you protect your system during healing.
Think of it like a battery. If you're feeling 20% better, don’t use it all at once. Let it slowly build to 25%, then 30%. Once you're at 70% or more, you can gradually return to a steadier routine.
Healing isn’t just about time. It’s also about respecting your limits. It’s crucial to avoid anything that puts more stress on your mitochondria. That includes:
😣 Emotional stress
🏋️ Overexertion
🍟 Processed food
🐟 Farmed fish
🍖 Non-organic meats
🍷 Alcohol
☣️ Toxic chemicals
🚬 Cigarette smoke
.......and especially other medications known to be mitochondrial-toxic:
→ Some antibiotics
→ Steroids
→ Anesthesia agents
We recently did a video about anesthesia on our YouTube: ▶️ https://t.co/lWJ0LMmfeq and in written form on our website: https://t.co/Vy5ujx5Hj9
Being mindful of all the above can help your system rebuild over time. Recovery is possible. It’s not always easy, nor is it by any means a straight path, but we’ve seen people come back from very dark places.
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Find support and resources on our sites:
🌐 Medical resources: https://t.co/gjkZgGyJ0V
🧭 Help & Misc resources: https://t.co/a63hkPq4Mv
▶️ YouTube: https://t.co/cjxhw1eSFu
🐦 X/Twitter: https://t.co/Gp9ZXyhyfZ
This post was an excerpt from our Foundation's video with the interview done by Talia Smith. See it here: https://t.co/qjcNwVdAMw
Medications in the fluoroquinolone class (incl: Cipro/ciprofloxacin, Levaquin (off market)/levofloxacin, Avelox/moxifloxacin etc) in all forms for humans and pets: https://t.co/OKH2DOWix0
Disclaimer: Fluoroquinolone Toxicity Study does not provide medical advice, and all articles and written content are intended for informational purposes only. We do our best to provide accurate information. Such information is not a substitute for professional medical advice, diagnosis or treatment. For multiple reasons, supplements, treatments, and pharmaceutical effects and outcomes can possibly vary significantly among those affected by fluoroquinolone drugs.
#FQAwareness #Fluoroquinolones #MitochondrialHealth #AntibioticSideEffects #Floxed #Cipro #Levaquin #FQAD
Beware of the ⚠️CHRONOTROPIC INCOMPETENCE ⚠️ in #MECFS from the real experts like @sunsopeningband et al. and @CornellMECFS
SoMEtiMEs going on based on your personal low heart rate (HR) is not guaranteed to not bring on a crash #PEM
Hypermobile Ehlers-Danlos Syndrome (hEDS) is the most common subtype of EDS characterized by a broad clinical spectrum affecting various organ systems including dermal, musculoskeletal, cardiovascular, and gastrointestinal.
Repost to raise awareness of hEDS.
Did you know?
> estimates suggest that LESS than 1% of all adverse drug events are reported to the FDA - so the below estimates are very low
> fluoroquinolone* antibiotics top the drug list at 107,659 adverse events
> #fluoroquinolone adverse events occur 4 times more than Corticosteroids, the second highest drug class at 26,911 adverse events
> 87% (94,656 records) of fluoroquinolone severe adverse events resulted in a life-threatening condition, hospitalization, disability, congenital anomaly, other serious conditions, or death
October 22nd is Fluoroquinolone Toxicity Awareness Day!
* For a list of drugs in the fluoroquinolone class (Cipro/ciprofloxacin, Levaquin (off market)/levofloxacin, Avelox/moxifloxacin etc) in all forms for humans and pets: https://t.co/OKH2DOWix0
References:
Events - Open FDA Reporting, 2004-present https://t.co/eNuY1cCQb0
HEALTH UPDATE:
It has officially been one year since I contracted Covid-19 while on set for my movie that I’ve been working on.
I was once a very healthy 31-year old man, but now every day is a struggle for me.
A THREAD... 🧵
“I’m not testing for Covid. If I’m sick I’m sick. What difference does it make?”
It makes a big difference. You SHOULD be testing. There’s things you should do differently if it’s Covid.
Governments & public health aren’t informing you - but that doesn’t change reality 🧵/1
After finishing a course of antibiotics in the fluoroquinolone (FQ) class*, you may be feeling quite worried if you're now experiencing sudden, jerking sensations in your body. What exactly are movement disorders (MDs), and how is it possible that widely-used antibiotics can result in such unexpected and largely unknown side effects?
Myoclonus** appears to be a common issue mentioned in patient support groups when experiencing various adverse effects beyond what’s listed in the package warnings. Could imbalances in GABA and glutamate levels be a contributing factor? This review article (see reference below) covers the FQ relationship with the following MD's:
**Myoclonus: refers to sudden, brief, involuntary muscle contractions or jerks. These muscle twitches can affect a specific part of the body or be more generalized, often appearing as a sudden and unpredictable movement.
Dyskinesia (rapid onset): is a movement disorder characterized by abnormal, involuntary, and repetitive movements. It can involve twisting, writhing, or jerky motions, and is often associated with conditions like Parkinson's disease or the side effects of certain medications.
Dystonia: is a neurological condition that leads to sustained and often painful muscle contractions, causing abnormal postures or twisting movements. It can affect specific body parts, such as the neck (cervical dystonia or torticollis) or the hands.
Cerebellar Syndromes: Cerebellar syndromes are a group of neurological disorders that result from damage to the cerebellum, a part of the brain responsible for coordinating voluntary movements. Symptoms can include incoordination, difficulty with balance, and tremors.
Ataxia: Ataxia is a neurological symptom characterized by a lack of coordination in muscle movements. It can result in unsteady gait, clumsiness, and difficulty with precise tasks like writing or buttoning a shirt.
Tic: A tic is a sudden, rapid, repetitive, and involuntary movement or vocalization. Tics are often associated with conditions like Tourette's syndrome. Motor tics involve movements, while vocal tics involve sounds or words.
Help may be found with a movement disorder specialist, which is a neurologist with further training and expertise specifically in movement disorders. Unfortunately, dealing with GABA issues remains tricky for FQ damaged patients; pharmacological approaches using GABA modulators and natural and lifestyle approaches are available, some to be approached with caution. Many do find that the twitching and jerking will dissipate with time but can be dependent on variables. Always research your options, and check to see how others are coping with these issues on the USA support group: https://t.co/E1ZlIJrCdm
Disclaimer: Fluoroquinolone Toxicity Study does not provide medical advice, and all articles and written content are intended for informational purposes only. It is not a substitute for professional medical advice, diagnosis or treatment. Supplements, treatments, and pharmaceutical outcomes can vary greatly between individuals.
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Rissardo JP, Caprara ALF. Fluoroquinolone-Associated Movement Disorder: A Literature Review. Medicines. 2023; 10(6):33. https://t.co/4F0MbQTbm4
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* For a list of drugs in the #fluoroquinolone class (#Cipro/#ciprofloxacin, Levaquin (off market)/levofloxacin, Avelox/moxifloxacin etc) in all forms for humans and pets: https://t.co/OKH2DOWix0
For toxicity warnings please visit our website: https://t.co/ZHd613H5qz
YouTube channel: https://t.co/Dha3E2SgnD
5. Also in Northern Ireland there are no #mecfs services, no clinical lead, the updated NICE guidelines have not been implemented so patients here can still come to serious harm. We also need representation at the All Party Parliamentary Group (APPG).