Dr. Alan John

Postdoctoral fellow at @WEHI_research
Synthetic Biology | Glycobiology | Proteomics | Chemical Biology.

[Seth Cheetham @SethCheetham]

We are recruiting for a senior research assistant to develop next-gen #mRNA drugs! The position within the @BASEmRNA research team will characterise new drugs across cellular and animal models. Apply below or contact @Mercerlab1 or myself for more info👇

https://t.co/CxGx6RaJNt

[David R. Liu @davidrliu]

Early in my academic career I was invited to give a seminar. It was before we had published much, so I was asked to give a talk on our lab’s research plans. Three people total showed up…but two left during my talk. I felt sorry for the last one, who must have felt so trapped.😂

[Nature Reviews Molecular Cell Biology @NatRevMCB]

New #NRMCBReview!
✨Context-specific regulation of extracellular vesicle biogenesis and cargo selection✨

by Andrew C. Dixson, T. Renee Dawson, @doldivizio & Alissa M. Weaver!

🔗 https://t.co/vSFUbppXeU

[Ethan Goddard-Borger @ethangbaus]

Tryptophan C-mannosylation and other glycans in Cryptosporidium parvum, now out in @jbiolchem

A wonderful collaboration with @Nick_E_Scott and @drchristonkin

Congratulations to all involved, especially co-first authors @DrAlanJohn and @stefaniembader

https://t.co/O3wqhSTBBH

[Science Immunology @SciImmunology]

A 2021 study from @DanaFarber @broadinstitute scientists yielded a new high-throughput screening methodology to identify specific #antigen parts, or epitopes, among peptide pools—akin to finding needles in a haystack. https://t.co/mi2Zh8ETnG @meyersonlab @mnleeee

[Wafik S. El-Deiry, MD, PhD, FACP @weldeiry]

T cells drive aging of the brain | Nature Immunology https://t.co/IbzfZpMMhj

[Ethan Goddard-Borger @ethangbaus]

How does nature catalyse C–C bond formation between protein and mannose?

The answer can be found in @nchembio today: https://t.co/a7adBPRb9q

This was a wonderful collaboration with @lab_locher, @Joel_S_Bloch, and many others. Congrats and thanks to all involved!

#glycotime

[Nature Chemical Biology @nchembio]

Work by @Joel_S_Bloch, @lab_locher, @ethangbaus reveals the structure, mode of peptide recognition, and catalytic mechanism of the eukaryotic C-mannosyltransferase DPY19. Open access: https://t.co/GpW3A0Pm6o #glycotime

[J. Andrew Alexander @J_A_Alexander]

I am ecstatic to finally share our work in @Nature where we investigated BlaR1, a signalling protein that controls resistance to β-lactam antibiotics in the major human pathogen, Methicillin Resistant Staphylococcus aureus. #MRSA #AMR #cryoEM
https://t.co/qslJWMwWNw
(1/n) 🧵

[Mo Khalil @MoKhalilLab]

Synthetic circuits that program new capabilities into human cells have tremendous potential to expand emerging gene and cell-based therapies. Our latest work, out today in @ScienceMagazine, reports a platform to accelerate these developments: (1/n)
https://t.co/YUORpuHuZ0

[Dr. Alan John @DrAlanJohn]

@Nick_E_Scott Congratulations Nick

[Dr. Alan John @DrAlanJohn]

@ethangbaus @WEHI_research @AlisonFarley14 Big congrats, Ethan. Well deserved.

[Ethan Goddard-Borger @ethangbaus]

It's an honour to receive the 2022 Burnet Prize from @WEHI_Research.

A big thanks to my team members, collaborators, and mentors (past and present) for their roles in making the discoveries happen.

Congratulations also to my co-awardee @AlisonFarley14 – well done!

[Dr. Alan John @DrAlanJohn]

@ElisaTelisa Hope you feel better soon, Elisa.

[Paras Sharma @paras_biotech]

Biopharma Industry Growth by Drug Modality
(2017-2026)

[2022 AGS & Warren Workshop @2022Ags]

Next up we have @DrBoddey telling us about glycosylation and it's role in mosquito transmission of malaria

[2022 AGS & Warren Workshop @2022Ags]

Next up @ethangbaus telling us about understanding C-mannosylation... You could say it will be exciting to "C" what his team has been up to

[Nichollas Scott @Nick_E_Scott]

My team and I are extremely grateful to @Cure4CFF for their support of our work and giving us this opportunity. Really excited to develop next generation Burkholderia vaccines using glycoengineering [🟨🟨🟡] 👩‍🔬🧪🧫🔬

[Jason Kelly @jrkelly]

Excited to share data showing @ginkgo platform applied to discovering next-gen CARs for use in cancer immunotherapy. Come visit our poster on Friday at #SITC2022 @sitcancer !! If you are at a biopharma company you can access this as a service now! https://t.co/JrSwbVj2Y9

[Joy Wolfram, PhD @WolframJoy]

Do cancer cells release sugar bubbles to hide from the immune system? Learn more about #ExtracellularVesicle #Glycans in our recent publication in @TrendsImmuno Jenifer Goncalves, Vatsal Deliwala, @Fer_NK_nando @DKolarich https://t.co/6DQ8N87618