Clint

Cancer & DOHaD researcher.
Support students, ask for help, never give up & don't be a dick.
Director

[Clint @DrClintGray]

The UK Motorcycle Podcast We’ve Been Waiting For | JUSTRIDE Podcast Ep.1 https://t.co/4p7cqeQyk4 via @YouTube

[New Scientist @newscientist]

We have identified the gene that, when activated, initiates the developmental programme that results in cells forming a human body https://t.co/JXb8s3lsHb

[Organoid News @organoidscience]

🧠 Researchers have developed human amygdala-like telencephalic organoids that model stress circuitry by connecting them with hypothalamic #organoids. @CellStemCell

▶️ https://t.co/POlSqU2Rll

[Biomedical Picture of the Day BPoD @BPoD_s]

Developmentally programmed p21+ senescent cells have a lifelong role in the integrity of the blood-brain & blood-CSF barriers

📹 L. Ashley Watson, Zoe Adelsheim & Mackenzie J. Carter et al Meharena lab @UCSanDiego in @CellCellPress
➡️ https://t.co/trnaNi7Xc2

[Science Advances @ScienceAdvances]

The protein GDF15—already shown to be a late-life indicator of dementia risk—may also be a midlife biomarker, new research finds. https://t.co/6xn2wOnQGO

[Journal of Cell Biology @JCellBiol]

How do cells recognize catastrophically damaged #mitochondria? Gao et al. identified MAI-1, the first genetically encoded reporter of severe mitochondrial membrane damage. This cytosolic protein translocates to damaged mitochondria within milliseconds. https://t.co/BwWtlgDepD

[MIT School of Engineering @MITEngineering]

In a @NatureBiotech paper, a team, including researchers in @MITdeptofBE and @MITChemE, developed a new way to stimulate the immune system to attack tumor cells, using a strategy that could make cancer immunotherapy work for many more patients.

https://t.co/LYGobgRVwr

[Stanford Medicine @StanfordMed]

Researchers at Stanford Medicine are developing immune cells designed to better recognize and attack cancer — offering a new approach to cancer treatment.
https://t.co/n9MoOlWZSJ

[Biomedical Picture of the Day BPoD @BPoD_s]

Enzyme MOS is key to successful meiosis

📷 Gisela Cairo & Muhammad A. Haseeb et al @GeiselMed in @J_Cell_Sci
➡️ https://t.co/JHl7BwQvr4

[Nature Biomedical Engineering @natBME]

mRNA delivery to the endothelium https://t.co/StLJeR9Zo3

[Science Magazine @ScienceMagazine]

Researchers in Science have created “cyborg” pancreatic organoids that combine stretchy miniature electronics with stem cell-derived pancreatic islets, using the implanted electronics to monitor electrical activity related to glucose regulation in maturing α and β cells.

The "cyborg" organoids offer a path to study the biology and trace the maturation of α and β cells at the single-cell level, with an eye toward potentially treating or engineering new pancreatic islets in people with diabetes.

Learn more: https://t.co/rfp287hX2z

[nature @Nature]

Nature research paper: CLCC1 governs ER bilayer equilibration to maintain lipid homeostasis

https://t.co/fXc3w9vTeP

[AJP-Cell Physiology @AJPCellPhys]

Interested in info about #vagus nerves? Then check out this #ArticleinPress, Comparison of Receptor Expression and Cholecystokinin Signaling Between Left and Right Nodose Ganglia (Caitlin R. Ritchey et al. @wsu):

https://t.co/wHn2HqUY7K

[Nature Reviews Biodiversity @NatRevBiodiv]

New online! Predator–prey interactions as drivers of cognitive evolution https://t.co/194vW1QMKf

[Science Magazine @ScienceMagazine]

Leveraging systems immunology, researchers characterize the distinct immunological profiles produced by #RSV and #SARSCoV2 infections in infants, providing data that explain clinical divergences and could inform future therapeutics. @ScienceTM https://t.co/nmtVcF7g6j

[Cris Muñoz-Pinedo & Ernest Nadal - PRETT lab @apoptosislab]

What happens when tumor cells can't find enough nutrients? They "call" other cells. We have found a new mediator of this phenomenon: the multifunctional cytokine LIF 👇

[Martin Picard @MitoPsychoBio]

The first physical evidence that mitochondria exchange information with one another transformed how I think about these beautiful organelles. From isolated beans to social collective.

In 2015, we discovered that the inner membranes of mitochondria, where the oxygen we breathe and food-derived electrons converge, somehow interact BETWEEN mitochondria.

This is the story, with videos and pictures, of how this happened while working with Meagan McManus @MitoLoveLab in Doug Wallace's lab.

https://t.co/LRE9ocZ2wT

[Aitor Viribay @MVAitor]

A paper I suggest reading if you are interested in Metabolism:

"Here we show that extracellular lactate acts in a dose-dependent fashion to increase oxidative phosphorylation and suppress glycolysis".

https://t.co/OZNhUKNVOO

[Dylan Burnette @MAG2ART]

Two cells isolated from a fish scale videoed through a DIC microscope. The cells are cool but now all I see are extracellular vesicles floating by in the media and stuck to the substrate....... #CellBiology

[eLife - the journal @eLife]

Can you infer cause and effect between genes without disturbing the cell? 🧬

This study shows how natural “noise” in gene expression can reveal directed gene–gene interactions.
https://t.co/3E1gHLldUr