Our work from the @Freudlab describing how the DNA repair protein APE1 binds and processes AP sites in the nucleosome is now out in @NatureComms!
@NIGMS@KUcancercenter
https://t.co/OTpAhPoJjS
Today, we announce the creation of the Gates Institute - a new institute to help scientists develop cell and gene therapeutics more effectively.
Learn more: https://t.co/1XHFJCZ6Rc
Please RT! Join us as a postdoc! Multiple funded positions available to study gene regulation in normal biology and disease. I am a passionate mentor, fostering innovative research and providing growth opportunities to meet your specific career goals.🧵
https://t.co/wArwjmWVeQ
Excited to finally share our new work from the
@Freudlab where we determine how the critical DNA repair protein APE1 recognizes and processes DNA damage in the nucleosome. Updated tweet 👇 (1/n)
https://t.co/XXHkts5pJU
ACS Chem. Biol. Visualizing Conformational Ensembles of the Nucleosome by NMR, Catherine A. Musselman* @MusselmanLab and Tatiana G. Kutateladze @CUAnschutz https://t.co/GgSmaQt6LC #NMRchat#NMR
This was an awesome collaboration with @epicypher ! The dCypher approach allowed us to test how the nucleosome alters the pattern of histone PTMs selected for by reader domains. The nucleosome context is critical for understanding reader function! 👇 @CUAnschutz@IowaBiochem