Duderstadt_lab

In our lab, hardcore biochemistry meets physics. And coffee. We are investigating DNA replication through single molecule loupe @MPI_Biochem.

[Duderstadt_lab @DuderstadtLab]

🚨Incredibly happy to share that our #ERCCoG project #ChromoMemInMotion is funded @ERC_Research. 🍾 We are grateful to the reviewers and panel members ! This was only possible thanks to amazing work of lab members past & present @MPI_Biochem & @TU_Muenchen. A dream come true🙏♥️

[Duderstadt_lab @DuderstadtLab]

We are grateful to TUM and @MPI_Biochem for their support and Margot Riggi for figure help. This would not have been possible without early support from SFB863, forces in biomolecular systems, and the European Research Council.

[Duderstadt_lab @DuderstadtLab]

🚨New preprint🚨We developed a transverse flow imaging approach to directly visualize bacterial replisomes challenged by topological barriers and discovered a fast rotational mode of replisome operation. Fantastic work by Thomas Retzer and Hamdan Lab! https://t.co/p8YYBlVtFN

[Duderstadt_lab @DuderstadtLab]

If you have not already, make sure to check-out two fantastic recent preprints from the Patel and Wang labs on the same topic investigated using magnetic tweezers and angular optical trapping:
https://t.co/OCW3Y1Hr8i and https://t.co/OYFNIafvi3

[Max Planck Institute of Biochemistry (MPIB) @MPI_Biochem]

Congrats on the Nomis Award, Elena @LabConti ! Her #NOMIS project aims to discern the structure and biochemical nature of #mRNPs in the brain throughout the #mRNA life cycle.

❗️https://t.co/nrXD8z0Mh2

[Miloš Tišma @TismaMilos]

Out today in @NAR_Open from @cees_dekker lab!!

*DNA supercoiling enhances DNA condensation by ParB proteins*

https://t.co/ZDJIxvbE1V

Together with @Aless322 (and @Gruber_Lausanne ) we show the interaction between partition complex proteins (ParB) and supercoiled DNA!

[Duderstadt_lab @DuderstadtLab]

@FMattiroli HUGE Congratulations! So well deserved! I can't wait to see what comes next! 🥳🍾

[Kazuhiro Maeshima @kazu_maeshima]

Thrilled to share our new work @biorxivpreprint:
https://t.co/6unXV2pn2C
Our Repli-Histo labeling marks nucleosomes in euchromatin and heterochromatin in live cells. We reveal genome chromatin is essentially replicated from regions with greater nucleosome motions. 1/2

[Max Planck Institute of Biochemistry (MPIB) @MPI_Biochem]

Read the latest publication from Danny Nedialkova’s lab and collaborators! In their latest work, they show that increased translation during the maternal-to-zygotic transition sensitizes maternal mRNA decoding rates to #tRNA supply.
❕https://t.co/U80qSuCoP5

@ddnedialkova #RNA

[Max Planck Institute of Biochemistry (MPIB) @MPI_Biochem]

Read the latest @Nature Perspective of Kikuë Tachibana's lab:

❗️https://t.co/sDYQq6c0lY

[Duderstadt_lab @DuderstadtLab]

@groth_anja @GrundforskFond @cancer_dk Fantastic news! Congratulations! 🎉

[Cynthia Wolberger @CWolberger]

A tour de force from Carl Wu's lab @JohnsHopkins .- lead author postdoc Robert Louder: Molecular basis of global promoter sensing and nucleosome capture by t... https://t.co/egfZFVetxW

[Duderstadt_lab @DuderstadtLab]

@GlattSebastian @VetmeduniVienna Congrats!

[Cynthia Wolberger @CWolberger]

We are hiring! Position open for a new assistant professor in the Department of Biophysics & Biophysical Chemistry in @HopkinsMedicine . Considering all areas in experimental and computational biophysics. Please spread the word. https://t.co/cAXosnT9rC

[Jungmann Lab @JungmannLab]

What makes for a great DNA-PAINT experiment? How does the fluorescent dye affect the image quality? And how can we use this to extract the most out of our samples?
Check out our paper in @NatureMethods to see what state-of-the-art DNA-PAINT can do for you!
https://t.co/RjvA4UeAfD

[Yeeles Lab @Yeeles_Lab]

We are excited to share new mechanistic insights into DNA replication fidelity! How does human DNA Polymerase Epsilon recognise and proofread errors made during synthesis? 🧬
Read @NatureSMB https://t.co/ZjkYugQaaq

[Duderstadt_lab @DuderstadtLab]

Cool video of eukaryotic dna replication! #molecularnodes

[Clockwork @this_clockwork]

Here's a render of a full eukaryotic replisome carrying out DNA replication. This was built using real .pdb data from @buildmodels

I used this to make my latest video: (https://t.co/zh2ImuLsOP)

But now I want to do a quick works cited 🧵 (1/ ?)

[Duderstadt_lab @DuderstadtLab]

@EAriasPalomo @Nature @CIB_CSIC @CSIC Congratulations! 🎉