DutchakLab

[DutchakLab @DutchakLab]

Can we target the drivers of genetic epilepsy?
Our new preprint shows RAPTOR-targeting ASOs reduce pathological mTORC1 activity, normalize neuronal hyperexcitability, and significantly extend survival in GATOR1-deficient mice. https://t.co/6jr9wLc2cd
#Epilepsy #Neuroscience

[DutchakLab @DutchakLab]

Special thanks to @BrainCanada, @CIHR_IRSC and @NSERC_CRSNG for supporting our research and trainee opportunities.

[DutchakLab @DutchakLab]

Could amino acid sensing determine the metabolic state of mature astrocytes and contribute to seizure susceptibility? Excited to share our new EMBO Reports study. Many thanks to an incredible team of collaborators and trainees.
https://t.co/9hGvDPkZ41

[Chantelle Sephton @ChantelleSepht1]

I am delighted to share our new publication! Huge thanks to Laetitia Marcadet, Marie Pelaez, and all of our outstanding co-authors for their contributions to this work. https://t.co/XdCxt5BaPs

[DutchakLab @DutchakLab]

Open Call: Newly funded graduate and post-doc positions available to research the convergence of nutrient signaling and genetics contributing to seizures, in Canada. #NIH #StudyAbroad #BrainResearch #epilepsy #MolecularNeuroscience
https://t.co/GdAwgnm0AM

[DutchakLab @DutchakLab]

Interested in mTORC1 and nutrient signaling mechanisms? New graduate student positions are available in our lab. #mTORC1 #nutrientsignaling #neuroscience #epilepsy

[Brain Canada @BrainCanada]

Grâce à une subvention Futurs leaders de la Fondation familiale Arrell, Paul A. Dutchak explore le lien entre la nutrition et les voies cérébrales. Cette recherche sur l'épilepsie et l'autisme vise à développer des stratégies nutritionnelles pour réduire les crises.

[TSC Alliance @tscalliance]

12th Annual Tuberous Sclerosis Complex Global Awareness Day Scheduled for May 15

Learn more: https://t.co/qd41VG2IJd

[DutchakLab @DutchakLab]

@ScienceMagazine @NewsfromScience Soylent green goop 🤨🤨

[Rare Epilepsy Network @RareEpilepsy]

Shout out to ALL person touched by the #rareepilepsies We stand with you on #EpilepsyDay and everyday!
@IlaeWeb @IntEpilepsyDay @IBESocialMedia @EpiCARE_ERN @geneticepilepsy

[DutchakLab @DutchakLab]

@ChantelleSepht1 Thank you for your help and collaboration in the project!

[DutchakLab @DutchakLab]

Congrats to all those involved in our dissection of epilepsy-linked mutations in GATOR1 and their influence on canonical PI3K:mTORC1 function! Stepping through the web of cell signaling to understand disease. #CERVO_ULaval #Universitelaval #neuroscience
https://t.co/nJsLYHwWdO

[DutchakLab @DutchakLab]

Un grand merci pour votre soutien à notre programme de recherche! @Pierre_Lavoie @rdmm_social #CERVO #CERVO_ULaval
https://t.co/9OK8CGmfLI

[DutchakLab @DutchakLab]

Antisense oligonucleotides targeting the miR-29b binding site in the GRN mRNA increase progranulin translation - Journal of Biological Chemistry https://t.co/vW3BHyhoms

[Ryan Reynolds @VancityReynolds]

I love these little pr*cks. Support @SickKids today.

[James Olzmann @OlzmannLab]

Tenure track Assistant Professor faculty position open at @UCBerkeley in nutrient signaling and metabolic biology (broadly defined). Metabolite sensing, regulation, signaling, flux, disease, etc. Please repost and help me get the word out. 😀
https://t.co/icWrPEZSZu

[Brain Ablaze @BrainAblaze]

Happy National Epilepsy Day to our friends in India 🇮🇳!

DYKT that conservative estimations suggest that there are over 12 MILLION people with epilepsy in India? #EpilepsyAwareness #EpilepsyAwarenessMonth #NEAM

[Chantelle Sephton @ChantelleSepht1]

Structural changes in motor neurons expressing FUSR521G precede motor impairment and other pathological features of ALS. Well done Mari @mcpelaez_ @silviapozzi81 @DutchakLab and colleagues!

https://t.co/o5dCSjtuk8

[CERVO @CERVO_ULaval]

PhD @ CERVO is an international graduate student recruitment competition to find outstanding students who want to study Neuroscience. To learn more and to submit an application, visit
https://t.co/1QqXObX4x0

[CERVO @CERVO_ULaval]

PhD @ CERVO est une compétition internationale de recrutement qui vise à identifier des étudiants exceptionnels intéressés à faire un Ph.D. en neuroscience. Détails et application ici: https://t.co/JMswtyYxW0

[DutchakLab @DutchakLab]

Our latest review is online! Check it out:
Synaptic dysfunction in ALS and FTD: anatomical and molecular changes provide insights into mechanisms of disease https://t.co/JSaalYVcEj
#neuroscience #ALS #dementia