I’d cancel your AG1 subscription. They just completed a clinical trial and the results show no clinical benefit.
This has been obvious for years. AG1 has no real product substance and is fundamentally an influencer heist.
Two simple alternatives (75% and 56% less $), outperform AG1 in randomized clinical trials.
Two simple mono-ingredient alternatives that outperform AG1:
1. Chicory inulin 12 g daily ($20/mo)
2. Resistant starch 30 g daily for 12 weeks ($35/mo)
AG1 is not worth $79/mo.
AG1 study results (4-weeks, N=30):
+ No significant changes in blood biomarkers compared to placebo (CBC, CMP, lipids).
+ No statistically significant improvement in digestive quality-of-life scores (p = 0.058).
+ No significant metabolic or inflammatory biomarker benefits of any kind within the scope of what was measured in the trial.
+ Only small shifts in microbiome taxa but clinically irrelevant at this stage.
+ The intervention did not increase microbiome diversity compared to placebo. Alpha diversity was unchanged, and the taxa changes seen were only from pre- to post-analysis within each group. Between-group differences were limited, and the placebo actually showed similar or even potentially larger shifts. This means the observed changes fall within normal placebo-driven variability, not a real treatment effect. No global microbiota shifts were detected.
Chicory inulin 12 g in constipation patients
+ 12 g of chicory inulin daily for 4 weeks (compared to maltodextrin placebo)
+ Global microbiota shifts: enrichment in butyrate-producing Bifidobacterium and Anaerostipes, and depletion of the pro-inflammatory Bilophila.
+The effect was seen by comparing intervention vs placebo in a cross-over setting, a very rigorous type of clinical analysis in which each person serves as their own control, eliminating a lot of individual random noise.
+ The trial also met its primary objective by improving constipation symptoms in the targeted patient group.
Resistant starch daily 30g for 12 weeks in older adults
+ Significant increase in Bifidobacterium in both middle-aged and elderly participants, with an increase in the beneficial microbiome byproduct butyrate, and reductions in Proteobacteria (including inflammatory Escherichia–Shigella) in the elderly.
+ Resistant starch also significantly reduced blood glucose, and produced greater reductions in blood insulin and insulin resistance (HOMA-IR) in the elderly group.
In 1931, a physician uncovered what he believed to be the true underlying cause of cancer but his findings were largely ignored by the world.
His name was Dr. Otto Warburg, and he went on to win the Nobel Prize for a discovery that could have fundamentally transformed the way cancer is treated.
We’re excited to announce that @YugaLabs has acquired the IP of both CryptoPunks and Meebits, along with the majority of developer-owned Punks and Meebits. Details here: https://t.co/DgCde8CLcD
✨ Announcing @_buildspace x @0xPolygon
Build your own ENS on Polygon in a weekend!
Instead of .eth or .sol -- you can have friends mint an even cooler domain on your own, custom domain service deployed to Polygon.
If curious, def sign-up!
https://t.co/reKTsXzS1q
The @itemfarm team will be hitting the road this/next week as we deliver an Orchard factory to Miami. If you're along this route and want to help us with a fun project shoot me a DM!
Lawmakers in the United States seem to be anxious about the crypto mining industry's electricity consumption levels as Senator Elizabeth Warren demands the top six companies to reveal their data. https://t.co/1kmdnd1OvN
🎉It's our 40th birthday this Friday and we want to see YOUR best birthday celebration creation using any Autodesk product of your choice🎉
Tweet your work with #ADSK40 or DM us for a chance to be featured on our socials!
This tasty render was created by Diego Avesani in Maya.
Push the boundaries of your craft with the latest updates in Maya! This release brings deformer updates, expansion of the modeling toolset, Channel Box support, and more. 🤩 #Maya3D See what's new: https://t.co/bh9w1Pux3M
🎙️ Join us in the Wilder World Discord Friday, Jan 28 at 12 PM PST, to hear @realfrankwilder & @Wolftech_eth talk about the process of creating the #WilderPets NFT Collection -- one of the most uniquely designed & rendered 3D/PFP projects to date!
💌👇
https://t.co/u3LjA6iYoS