Fikri Birey

Assistant professor @EmoryUniversity @EmoryGenetics.
Human brain development & disease + stem cell-based models.
@BrainOrg_Hub

[Fikri Birey @fikribirey]

Such a thrill to see our work on developing genetic theraputics for Timothy Syndrome on the cover of @Nature today. One of the most gratifying projects i've ever worked on, alongside @XiaoyuChenxy with @Sergiu_P_Pasca at the helm. Excited for what lies ahead for dev. theraputics!

[Sergiu P. Pasca @Sergiu_P_Pasca]

Today, I’m thrilled have our lab’s work featured on the cover of @Nature

In this article, we have developed a therapeutic approach for a severe condition called Timothy syndrome. This has been a long journey. It started with making hiPS cell-derived neurons in 2D cultures 15 years ago when I was a postdoc and continued with later creating in the lab #organoid and then #assembloid models of this disease caused by a mutation in a calcium channel.

Over time, these human cellular models and the biological insights we gained enable us to design a therapeutic strategy, which we validated in vivo following circuit integration of patient-derived organoids into the rat brain.

Grateful for the incredible work led by @XiaoyuChenxy and @fikribirey in the lab! And the many close collaborators who participated to this line of research over the years.

[BrainOrganoidHub @BrainOrg_Hub]

We're excited to announce that the Brain Organoid Hub is hiring! If you, or someone you know, has an interest in working with stem cells and brain organoids as a Research Specialist, please feel free to apply 🔬https://t.co/STWEu4sJVY

[Fikri Birey @fikribirey]

@TarunNBhatia1 @AmericanCancer @Sloan_Lab Huge congrats!!🍾🎉

[BrainOrganoidHub @BrainOrg_Hub]

It was so fun to see these talented scientists work hard to master iPSC/organoid techniques in record time! We are so proud of our first workshop cohort and can't wait to see how they incorporate organoids into their science. Sincerest thank you from all of us. 🫶

[Fernando C. Alsina @alsina_fc]

Our lab @StJudeResearch is recruiting! We have postdoc and technician positions available.
Please apply (links below) if you’re interested in neural differentiation and maturation during brain development and disease focusing on novel concepts of mRNA and cytoskeletal regulation

[Sergiu P. Pasca @Sergiu_P_Pasca]

Our newest work is online now in Neuron @NeuroCellPress showing the generation of diencephaluc #organoids, assembly to form cortico-thalamic #assembloids and their application to discover defects following loss of function and gain of function mutations in CACNA1G, which are associated with high risk for schizophrenia and absence seizure epilepsy, respectively.

Work spearheaded by Ji-il Kim, Yuki Miura and @Minyin_Li

[Lola Irala @IralaDolores]

Are you interested in synaptic balance, astrocytes, neurons, and neurodevelopmental disorders? The Irala lab is recruiting and we have postdoc and technician positions! They come with incredible benefits and support! Please apply following the links below to join our team 🧬✴️

[Fikri Birey @fikribirey]

Excited to welcome our participants next week for the First Emory Brain Organoid Hub Workshop—a 5-day training marathon on everything brain organoid!🧠

[BrainOrganoidHub @BrainOrg_Hub]

Come join the Brain Organoid Hub this October for a hands-on and immersive workshop to learn the ins
and outs of brain organoid culture! We will be offering in-depth training, expert lectures, and practical demos. Apply now at https://t.co/slRsdEFLmA.

[Fikri Birey @fikribirey]

@fennamk @NIH_CommonFund @PrincetonNeuro Huge congrats!! 🎊

[Neural Cell News @NeuralCell]

🤩 We can't wait for #ISDN2024 this weekend!

Don't miss Drs. Benedetta Artegiani (@BArtegiani), @Alex_Baffet, @fikribirey, & @SilviaM_Velasco discuss 🧠 #organoid modeling of CNS development.

Find the program here: https://t.co/APup3rg366

[Fikri Birey @fikribirey]

@XiaoYang63 @JohnsHopkins @JHUBME Huge congrats Xiao!! 🎉

[Fikri Birey @fikribirey]

@LCneuroscience @TarunNBhatia1 @BrainOrg_Hub Shoutout to @BrainOrg_Hub member Zihui Ou for capturing this beautiful snapshot!

[Sulagna Das @angalus_d]

Our lab is growing and we have openings for #postdoc and #technician. Please get in touch if you are interested in #RNA regulation in #neurons or #gene expression studies. RT or share. Learn more on our lab website: https://t.co/YfqdGMkE8L

[Simons Foundation @SimonsFdn]

It is with great sadness that the Simons Foundation announces the death of its co-founder and chair emeritus, James Harris Simons. Jim was an award-winning mathematician, a legendary investor and a generous philanthropist. https://t.co/w48DhauUVj

[Director, National Institute of Mental Health @NIMHDirector]

A recent @NIH-supported study discovered a potential new therapy for Timothy syndrome, a rare genetic disorder. The findings could offer a road map for treating other rare genetic conditions and mental disorders, too. Learn more: https://t.co/5qdXtgC4Hj

[Fikri Birey @fikribirey]

Huge congratulations!! 🎉🎊

[Jimena Andersen @jimena_andersen]

So excited to be a recipient of the Tambourine ALS Breakthrough Research Fund! Our project will use 3D human cellular models to study mechanisms underlying ALS. Thanks to Tambourine for this support! More here: https://t.co/gx2yFevqkR

[Lasker Foundation @LaskerFDN]

Using a multilevel in vivo and in vitro stem cell model-based approach, scientists rescue neuronal function in cortical organoids derived from patients with #TimothySyndrome –a severe, multisystem disorder.
@XiaoyuChenxy @fikribirey @Sergiu_P_Pasca
https://t.co/Fzial11wvT

[NIH Innovates @NIH_Innovates]

In a proof-of-concept study, researchers show the effectiveness of a potential new therapy for Timothy syndrome, an often life-threatening & rare genetic disorder. This research also offers insights into other rare genetic conditions & mental disorders. https://t.co/I1sKaC8WKE

[fenna krienen @fennamk]

‼️Job alert! ‼️ multiple #postdoc positions open in my lab @Princeton.
Interested in single cell #genomics & brain development?

#studyBRAIN projects, cell type tools for 🐒🧠, weird evolutionary phenomena (chimeric microglia??)

Check us out https://t.co/pbpmXa1ipv & pls RT!

[Nuri Smith (she/her) @NURIeSMITH]

From @NSF GRFP Honorable Mention to Awardee 🎉
Huge thank you to my amazing PI @jimena_andersen and my previous mentors/letter writers @martinowk, @SvitlanaBach, and Dr. Kimberly Shorter!
I can’t believe it!
@emorygmb