Gastro-oesophageal adenocarcinoma is a global challenge, ranking among the leading causes of cancer mortality.
This Editorial looks at the fundamental clinical question on how to balance treatment goals against sustainability
https://t.co/4mCzci9F2z
In this review we go through the key aspects that characterize MSI-H/dMMR cancers, in light of recent diagnostic advances and the successes of immune checkpoint inhibitors in both advanced and early stage disease.
Have a look!
https://t.co/w1qvKYnwvI
Shorter ICI tx for dMMR/MSI-H mCRC isn't detrimental - may spare toxicities, costs and preserve QoL. Explore the findings from our study in @jitcancer & stay tuned for a future clinical trial on this question!
Thx to my mentors and all the contributors! 🇫🇷🇮🇹🇪🇸🇺🇸
Brilliant, solid, impeccable presentation at #ASCO24 by the one and only @FilippoPietran4. The road is still long and winding, but ARMANI is yet another step towards the optimisation of care for pts with gastric cancer. Congrats to all involved in this amazing academic effort.
✨Excited and honored to can finally share our work about the rare and important subgroup of POLE/D1 proofreading deficient (pd) mCRC treated with ICIs across 🇪🇺🇺🇸🇮🇱
@FilippoPietran4@paomanca@BenjcRousseau@myESMO@Annals_Oncology
https://t.co/T1xboSKHIO
For details🧵⬇️
KEYNOTE-585 is published @TheLancetOncol as presented at #ESMO24. Pembro+chemo improved pathCR of #gastriccancer but EFS was not statistically significant. MSI-H is distinguished population. Full results of Matterhorn awaited. @OncoAlert@myESMO@ASCO
https://t.co/AZrAItXLJV
Original Article: Sotorasib plus Panitumumab in Refractory Colorectal Cancer with Mutated KRAS G12C (CodeBreaK 300 phase 3 trial) https://t.co/mLuAayTmTM
#ESMO23#oncology