HydroGym: A Reinforcement Learning Platform for Fluid Dynamics
Now published in Nature!! https://t.co/o1zTn2DIHg
GitHub: https://t.co/9MLBzJAMiJ
Amazing collaboration with Christian Lagemann, S Mokbel, M Gondrum, M Rüttgers, Y Wang, P Suárez, L Paehler, D A Bezgin, A B Buhendwa, J L Callaham, S Ahnert, N Zolman, X Shao, J-Ch Loiseau, N A. Adams, M Meinke, W Schröder, K Lagemann, E Lagemann, R Vinuesa & S L Brunton
Can a model still find value against Pinnacle's tennis prices? A University of Bristol paper (Clegg & Cartlidge, Oct 2025) is an unusually honest data point.
Their graph neural network targets intransitive dominance patterns — A beats B, B beats C, C beats A — the structure that Elo-style ratings compress away.
As a forecaster it does NOT beat the market: 65.7% accuracy / 0.215 Brier vs 69.0% / 0.196 for Pinnacle's implied probabilities.
But restricted to high-intransitivity matchups, betting the model returned +3.26% ROI over 1,903 bets with Kelly staking (p = 0.005), and +1.14% over 2,063 bets flat (p = 0.022).
The takeaway is not "GNNs beat the market". It is that inefficiency survives in structured pockets that the aggregate line does not fully price.
Source: https://t.co/qWXwWZLUcC
@SolidEvidence@StuartTurville Speaking of SARS-1, the authors did the same experiment on the SARS-1 RBM and found that a single mutation rapidly emerged & was sufficient to increase its ACE2 affinity to well above WT SARS-2 levels (on graph, lower = higher ACE2 affinity).
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@SolidEvidence@StuartTurville We may have been one mutation away from a global SARS-1 pandemic. We've seen a novel coronavirus emerge & spread in humans about every 10 years since 2002. Studies that help us learn as much as we can from this CoV pandemic help prepare us for the next one.
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Another fascinating study from the Schreiber lab. When BA.1 emerged, I saw its spike RBD muts & thought Q498R looked familiar. It was, but not because I'd seen it in a virus sequence. It was because this lab predicted it months before BA.1 showed up. 1/37
https://t.co/eOD2DFmqDL
@umbra_cursor За последние 20 лет ЮАР прошла путь от лидера африканского континента с самым оптимистичным будущим до государства, столкнувшегося с глубоким системным кризисом. Из-за коррупции, проблем в управлении страна потеряла статус крупнейшей экономики Африки, уступив его Нигерии
@umbra_cursor Ладно обезьянки, им можно)). Помню как смотрел концерт в поддержку борца с апартеидом состоялся 11 июня 1988 года на стадионе «Уэмбли» в Лондоне. Free Nelson Mandela Concert. Хедлайнеры: легендарные мировые звезды, Стинга, Уитни Хьюстон, Стиви Уондера, Dire Straits, Queen