Germán Fernández V.

Sometime cyclist and sometimes Biomed PhD.

[Germán Fernández V. @GermanLFV]

First results of an object recognition model
built with @DeepLabCut and SimBA (@GoldenNeuron)
Trained on our own dataset, fine-tuned with Model Zoo.
Still a work in progress — but already looking solid! 👨‍🏭

[Decision Neuroscience and Neuroeconomics Papers @decisionneurop]

Striatal pathways dissociably control action counting and goal-directed steering https://t.co/JuvQTpXWyw

[Neuron @NeuroCellPress]

Online now: Rapid strengthening and reversal of hippocampal-neocortical interplay mediates human memory formation https://t.co/NRmgUlIXHx

[CLaE @leafs_s]

Nature

BOOK REVIEW

How to breathe life back into brain theory

Neuroscience needs to stop treating the brain as if it is a computer.

https://t.co/FpBBmLfwwV

[CLaE @leafs_s]

Nature Human Behaviour

Hybrid neural–cognitive models reveal how memory shapes human reward learning

This paper shows that human reward learning cannot be fully explained by simple reinforcement learning models based only on gradually updated reward values.

Using a large human decision-making dataset, the authors built hybrid neural–cognitive models that combine interpretable cognitive models with neural networks. They found that people use richer and more flexible memory representations of past experiences than standard Q-learning models assume.

Overall, the study suggests that reward-based learning depends not only on scalar reward predictions, but also on complex memory of past actions, rewards, and context.

https://t.co/MhgP9uMPiv

[Cell Press @CellPressNews]

"Intralaminar thalamus relays basal ganglia output to the insular cortex to drive tic generation" https://t.co/5aQvanxePG

Yoshihisa Tachibana & colleagues
@CellReports

[TK Kozai (BIONICLab.org) @BIONIC_Lab]

For ~100 years, neuroscience assumed electrical stimulation excites neurons. Deliver current, cells depolarize, done.
That assumption is wrong.

[Science Magazine @ScienceMagazine]

A 2024 special issue of Science explored the complex and close associations rats share with humans—from their ubiquity in the human environment to their crucial role as biomedical models.

🐀 Learn more on #WorldRatDay: https://t.co/fA5UFv0u8r

[Germán Fernández V. @GermanLFV]

https://t.co/J9lSZqo5F2 #Neuroscience #Electrophysiology #OpenScience

[Germán Fernández V. @GermanLFV]

Built a custom analysis pipeline in @wavemetrics igorpro for Heka patchmaster electrophysiology data.
✔️ Automated batch processing
✔️ Baseline correction & detrending
✔️ Passive membrane properties (Cm, Rs)
Designed around real experimental constraints and reproducibility

[Germán Fernández V. @GermanLFV]

Un estudio acaba de mapear por primera vez, y en detalle la inervación del clítoris. Importante para cirugías de género y reconstrucciones. https://t.co/aogydKhqfC #Ciencia

[Germán Fernández V. @GermanLFV]

Muy bien @DeProvidencia @TTISantiago @Orrego

[Germán Fernández V. @GermanLFV]

Happy to share the news! 🎉 I had the pleasure of collaborating on this new article that delves into the gating mechanism of mechanosensitive ion channels OSCA1.2 using unnatural amino acid photo-crosslinking. Hope you like it! https://t.co/kQOmrwTyAE @Vrid_Unab

[Germán Fernández V. @GermanLFV]

Applying the FAIR Principles to computational workflows | Scientific Data https://t.co/aUsIVdfbu1

[Germán Fernández V. @GermanLFV]

@ballacey @MuniVitacura Real, en la misma avenida vitacura

[Germán Fernández V. @GermanLFV]

Thrilled to share the publication of my PhD thesis! Using AAV9 to deliver a Zinc Finger–VP64 ATF at birth, we restored hippocampal PSD95 levels and improved memory and motor learning in HD mice—combining behavioral, molecular, and spine analyses. #HuntingtonsDisease, #Epigenetics

[Germán Fernández V. @GermanLFV]

@1991Gabri @FcoDarmendrail @TVN estan todas disponibles en el sitio de la @CinetecaChile y creo que en TVN play tambien.

[Germán Fernández V. @GermanLFV]

@pamdastik Y no saludar en la calle

[Germán Fernández V. @GermanLFV]

@danimanouchehri @GabrielBoric Recordemos cuando pompeo llamó a Piñera y esto paralizó el proyecto de fibra óptica de Wahuei

[Germán Fernández V. @GermanLFV]

Precision epigenetic editing: Technological advances, enduring challenges, and therapeutic applications: Cell Chemical Biology https://t.co/UDsaJwvSKQ