Crocker Lab

We are the research lab of Dr. Steve Crocker at the University of Connecticut School of Medicine. We study demyelinating diseases of the central nervous system.

[Journal of Experimental Medicine @JExpMed]

CD8+ T cell depletion prevents neuropathology in a mouse model of globoid cell #leukodystrophy, say Pearl Sutter, Stephen Crocker @GlialLab @uconnhealth and colleagues https://t.co/6FDnA0yuSG

#Neuroinflammation

[John Lukens @LukensJohnR]

Role for CD8+ T cells in driving the neuropathology underlying Krabbe’s disease

CD8+ T cell depletion prevents neuropathology in a mouse model of globoid cell leukodystrophy https://t.co/0WFN24S7Ja

[Crocker Lab @GlialLab]

Excited to share our most recent findings on The Cellular Senescence Factor Extracellular HMGB1 and its impact on CNS Remyelination. Great collaboration with @jeffreyhuang Thanks @mssociety ! https://t.co/8eN7IBbUWz

[Jaime Imitola MD., FAAN @DrJim4MS]

👇@UConn #nation #MS care is a big unmet need in #CT. Join our #MS🚶‍♀️and support research and service programs @mssociety. @MarinaC_Dyb @uconnhealth @UConnResearch @UConnNeurology @UCHI_UConn @UConnWBB @UConnFootball @CTDPH @GlialLab @UconnAging @UConnHartford @TheHartford 💪🧠👏

[ISNI-The International Society of Neuroimmunology @ISNI_neuro]

The abstract submission date to #ISNI Virtual France 2021 is on September 17. Join our invited speakers and be part of our fantastic program. More info on website: https://t.co/0iivDrhuhr

[Jaime Grutzendler @JGrutzendler]

The Grutzendler lab at Yale has an opening for a postdoctoral fellow to study neuroglial biology in health and neurodegeneration. Required background in molecular/cellular/physiology. Interested individuals please send letter and CV to: [email protected]

[L Peruzzotti-Jametti @Dr_LPJ]

Read, enjoy, and share our latest research on #mitochondria and #NeuralStemCells @PLOSBiology! Thanks to @exosomeguy @grzkrzak @GManferrari @NNZ79 @vicarionunzio @GourmetJesus @tom_leon @bragaalice1 @Erikafvb @aletta_vdbosch @CrisBenincaPhD @CarloViscomi @FrezzaLab @Pluchinolab

[The Nobel Prize @NobelPrize]

BREAKING NEWS:
The 2020 #NobelPrize in Chemistry has been awarded to Emmanuelle Charpentier and Jennifer A. Doudna “for the development of a method for genome editing.”

[The Nobel Prize @NobelPrize]

BREAKING NEWS:
The 2020 #NobelPrize in Physiology or Medicine has been awarded jointly to Harvey J. Alter, Michael Houghton and Charles M. Rice “for the discovery of Hepatitis C virus.”

[Crocker Lab @GlialLab]

Thank you @Pluchinolab , @Telencephale and @exosomeguy . Important emerging topic, and great collaborators ! #aging

[Alexandra Nicaise @Telencephale]

Check out our new review on neural stem cells and ageing with a focus on in vitro modeling 👩 ➡️ 👵 https://t.co/rUC5jYA1kW with help from @exosomeguy @GlialLab @Pluchinolab

[Crocker Lab @GlialLab]

I pledge to oppose racism and hate and be anti-racist hrough active allyship, continuous learning and listening.

[Cory Willis @exosomeguy]

@cory_raquel @mpbutler639 @sophieleegough @MatthewDurst @MDPhDToBe @stevenxchen @TLeungMD @MAACPGovernor @BobDohertyACP @drakb1 @jasongoldmanmd @sue_bornstein @PDX_Tom @ChristieReimer @bobpmd @PrestonWilesMD @BillFoxMD @doudel @SEricksonACP @TaniMalhotraMD @sarahgcandler @IanMotie @ChrisLibbyMD @AvaniPatelMD @yejnes @DarilynMoyer @MParshleyMD @hemphillr @doctorbecca1 @lisa_camara1 @MCarneyMD @jakequintonMD @ryankraemr @FStPierreMD @RGuerrieriMSTP @E_Rose_1 @CLCockburn @kevincmiller13 @cobbnotgrey @GwendolynDerk @AlexCerjanic @spencermamer @cjkonopka @youngMuDPhuD @the_matelski I pledge to be anti-racist through active allyship, continuous unlearning, learning & listening. Join me by nominating 5 others to do the same. @Telencephale @Dr_LPJ @GlialLab @PijewskiRobert @aletta_vdbosch

[Crocker Lab @GlialLab]

A thought: when the bubonic plague swept across Europe in 1665-66, Isaac Newton retreated to the country from Cambridge University. Many of his most notable scientific contributions, including motion, optics and gravitation came from his Annus Mirabilis: his “wonderful year.”

[Crocker Lab @GlialLab]

This COVID-19 social isolation, working from home, endless e-mails, watching the same intrepid joggers pass the house each morning, sometimes makes me feels like @BillMurray living in a loop...

[John Wallingford @jbwallingford]

Let's hear it for GenX:

https://t.co/rskoQc3Sue

[Crocker Lab @GlialLab]

Grateful for the opportunity to advocate for legislation to benefit #MultipleSclerosis patients with the #NMSS on Capital Hill, including increased funding NIH! #msppc20

[Crocker Lab @GlialLab]

Pleased to have been asked to advocate for #MSresearch on Capital Hill at this year's National MS Society Public Policy Conference! #MSPPC20

[Crocker Lab @GlialLab]

Nice study from Hellings and colleagues linking one of our favorite proteins, TIMP-1, to #remyelination in multiple sclerosis. #astrocytes https://t.co/YvGgY5mwhq

[Crocker Lab @GlialLab]

The importance of language and its use in an engaging and humorous article. How much of this is spreading in academia? https://t.co/XZqYE6ezLU

[Immunity @ImmunityCP]

.@SchaferLabUMMS @s_werneburg &co Synapse loss can occur early & prior to other #MultipleSclerosis-relevant pathology & is associated with synapse-localized complement C3. AAV approach to inhibit C3 protects synapses & preserves circuit function https://t.co/ehhuqraa1q @GlialLab

[Crocker Lab @GlialLab]

Our new studies reveal that aging of astrocytes changes EV #exosomes function to dramatically reduce support for oligodendrocytes and also confer age-related responses on naive cells. Grateful to terrific collaborators who contributed this work. @UConnResearch @jacksonlab

[Cory Willis @exosomeguy]

Very excited that our work on how ageing influences astrocyte #ExtracellularVesicle content and function have been published in @SciReports (https://t.co/Yy3XIV5num) and Neurochemical research (https://t.co/lfjKotjRMb)! Special thanks to @Gliallab and all co-authors!