Very proud to share our latest work, carried out with remarkable dedication by Léa and Claire.
Thanks to JCS for the Highlight, but also the wonderful First Author profile featuring Léa and Claire, as well as the journal cover showcasing the work.
Léa Marpeaux, Claire Baudouin, Gregory Emery @GregoryEmery8 and colleagues @IRIC_umontreal identify an apical supracellular actin network in epithelial cells that acts as a long-range force transmission device.
Highlight: https://t.co/YfWjSNkUkT
Article: https://t.co/WX4S3BFJ2X
🎉CIHR names 12 researchers as Outstanding Peer Reviewers for going above and beyond –providing exceptional reviews & taking on extra tasks– to strengthen health research in Canada.
Thanks for your time, insight and leadership. Your contributions matter.
https://t.co/zpSPti1dJ0
To our knowledge, this is one of the first publication that describe a role for a Rap2 ortholog in vivo.
Great work by Gabriela (who just defended her PhD, summa cum laude) and other people from our group, with the help of the labs of Marc Therrien and Tom Moss. (3/3)
Our latest work on the regulation of collective cell migration is out !
Please check it out ! (1/3)
Tao and Rap2l ensure proper Misshapen activation and levels during Dro... https://t.co/Gs1N7FSYrF
We identified that the kinase Misshapen, which is central to the coordination of border cells migration in the Drosophila egg chamber, is regulated by the kinase Tao and the small GTPase Rap2 (Rap2l). They control the activation and the levels of Misshapen, respectively. (2/3)
Happy to share that Lara's beautiful image showing the reorganization of actin in clusters of epidermoid carcinoma cells after the inhibition of MAP4K4 has been selected for the cover of the september issue of @LSAjournal. #FluorescenceFriday
https://t.co/bykLK9Sood
This great work by Alison adds to our understanding of the regulation of guidance receptors during collective migration by involving ArfGAP1, Lrrk and Hrs. It also increases our understading of the role of the GTPase and kinase Lrrk.
Hi everyone, our latest paper is now out in iScience. In previous work, we performed a screen to identify regulator of vesicular trafficking involved in the collective migration of border cells. Alison Boutet decided to focus on ArfGAP1.
https://t.co/kkXOVeMegg
Lrrk is a GTPase and a kinase that regulates vesicular trafficking by acting on several Rab GTPase. In particular, Lrrk acts with Hrs to participate in the sorting in early endosomes. Genetic interactions indicate that ArfGAP1 regulates Lrrk and Hrs to block RTK degradation.