Repeated concussions can change the brain over time.
New research from MUSC shows that immune activity may play a major role in long term damage after mild traumatic brain injuries.
Find out more: https://t.co/FvAD24Z7FG
#ChangingWhatsPossible
(2/2) Also, none of this work could have been possible without Dr. Silvia Guglietta (@GugliettaLab), Dr. Stephen Tomlinson, and all the contributing authors. @MUSChealth
🔥📢BIG NEWS!
(1/2) I'm excited to share our accepted paper in Nature's Signal Transduction and Targeted Therapy (@sigtrans_sttt) showing a role for complement in repetitive closed head injury. Many thanks to @ResearchMUSC@DeptVetAffairs@NIH@biaamerica
https://t.co/yFIWILpion
🚨Our team @GugliettaLab@KhalilMallahPhD just published in Signal Transduction & Targeted Therapy: 10.1038/s41392-025-02466-7. Repetitive mild head injury activates brain’s complement system—driving inflammation&memory loss. Complement blockage protects. @MedUnivSC@ResearchMUSC
We performed a multi-omic characterization of the immune landscape in our new model of repetitive traumatic brain injury and identified the mechanisms associated with the protective role of complement inhibition. Great teamwork @GugliettaLab@KhalilMallahPhD@CarstenKriegPhD
Happy to share that our article on the role of the complement system in intestinal inflammation and colon cancer is now published in @jclinicalinvest. Great team work @CarstenKriegPhD and @GugliettaLab
The complement system in intestinal inflammation and cancer
As part of JCI’s Review series on complement biology and therapeutics, Carsten Krieg & Silvia Guglietta @GugliettaLab@MedUnivSC et al. highlight the complement system in the GI tract under homeostasis, #inflammation, and during tumor development, progression, and treatment: https://t.co/Kks9gOOMhP
This week on Health Focus, Hollings researcher Dr. Silvia Guglietta talks about her work on immunotherapy in colon cancer. Listen on your SC Public Radio station, or check out the website! https://t.co/y5XWeTeT1n
Cool work from @IlievLab and collaborators: Fungal symbiont transmitted by free-living mice promotes type 2 immunity | Nature https://t.co/uATs5sEGxR
Have you applied for your IMMUNOLOGY2025™️ travel award? Boost your professional development in May! Whether you're with a Laboratory, #Undergrad, #EarlyCareer - apply today: https://t.co/VMuSxf4fJ2. #AAI2025#IMMUNOLOGY2025
Complement factor H is an ICOS ligand modulating Tregs in the glioma microenvironment | Cancer Immunology Research | American Association for Cancer Research https://t.co/UqKbWRmQIk
Interested in benchmarking computational methods in computational biology, generally?
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Conference website:
https://t.co/wBqBh5yFj4
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