Are you a wet lab biologist ready to shape the future of AI in genomics? CSHL is hiring a PhD-level Research Associate to join a collaborative team of genomic scientists and AI researchers. Help build the next generation of AI models for genomics!
plz RT
https://t.co/LWNmcnYIoc
🌟 Excited to announce AMPLIFY, our latest protein language model that challenges the scaling trend! While current models like ESM2 15B rely on billions of parameters, AMPLIFY achieves superior performance with only 350M parameters. 1/7
Excited that CREME (Cis-Regulatory Element Model Explanations) is published in @NatureGenet! Work led by @ToneyanSh!
tl;dr CREME interprets rules of gene regulation learned by genomic deep learning models using carefully designed in silico perturbations.
https://t.co/K4UC0eDSZZ
PlantCaduceus - Cross-species modeling of plant genomes
Led by Jingjing Zhai and Aaron Gokaslan, with the Kuleshov lab, we’re having our “ChatGPT moment” with DNA Large Models. PlantCaduceus predicts functional DNA sequences with single base resolution across flowering plants.
📣 Come join us for a 3-day intensive course in Data Analytics and Digital Tools Applied to Livestock Production 6-8 November 📣 Instructor: @gjmrosa. 📣
Read more and sign up here: https://t.co/e7SHslHwRJ
#DataAnalytics#DigitalTools#Livestock
@GebreGrum @GoutamSahana
Join us for our next Kipoi Seminar with Thomas Pierrot
@thomas_pierrot@instadeepai!
👉The Nucleotide Transformer initiative: building and evaluating robust foundation models for genomics
📆Wed May 8, 5:30pm CET
🧬https://t.co/crpXzuYkhP
Two new chapters from my open-access textbook in human population genetics are now online:
- Population structure: I. Ancestry estimation
- Population structure: II. More about admixture
https://t.co/GHMPCTv6BL
We have received lots of interest in AlphaMissense, the @GoogleDeepmind model predicting the probability of a missense variant being pathogenic, since its release in September. Today we are updating the license terms for AlphaMissense predictions to also allow for commercial use.
If you have a Ph.D. in population genetics, computational biology, or bioinformatics and an interest in human health, you should come to Denmark for your postdoc and help us understand the role sex chromosomes play in autism. https://t.co/SQBrbE7TT8
🌱🚨 Exciting news! We're launching a company to develop next-gen crop breeding tools, speeding up seed-to-seed generation time. Seeking experts in plant biotechnology, AI/ML, and agricultural biotech commercialization. Links in comments 🚨 🌱
I've written up a "crash course" on population genetics parameters useful for thinking about recent selection, heritability, and group differences (as part of a longer write-up on these concepts).
https://t.co/WoObQLpxB2
I'll summarize the key points here 🧵:
Congratulations to all the collaborators, and thanks very much for all your efforts and supports! Looking forward to more fantastic outcomes from the FarmGTEx in the coming year.@QGG_AU @NatureGenet https://t.co/4ZKen4UaYl
New from Lippman Lab and recent PhD grad Dani Ciren on bioRxiv: “A striking paradox is that genes with conserved protein sequence, function and expression pattern over deep time often exhibit extremely divergent cis-regulatory sequences.” More inside…
https://t.co/ij7aIPQfOc
Save the date 📆:
The 2025 @GordonConf on Quantitative Genetics and Genomics is scheduled for Feb 16-21, 2025 in Lucca, Italy (pics from 2019!) 🤩
Josephine Pemberton and I co-chairing, tentative theme: Quantgen in time and space 🕛🌿
Associated GRS: Feb 15-16 ✨
More soon!
A few thoughts on the recent set of papers torture testing genomic deep learning for predicting individual-level gene expression [ https://t.co/rRUBH7sW6m , https://t.co/ZLcoXGPbWD , https://t.co/Je9pFg4kX2 ]. First a brief summary 🧵:
https://t.co/yUKnoeeA4r