Hunter B Dean

MD/PhD Candidate in @RobersonLabUAB • @UofAlabama '16 • Molecular simulations are just grant-funded computer games #compchem #doubledocs

[Hunter B Dean @HBDeanMSTP]

I promised my labmates I'd make a Twitter profile when my first research paper hit Pubmed, but apparently I was here already

[Tom Brett @tombrettlab]

Nice computational work on TREM2 showing non-local structural perturbations may be caused by AD-linked TREM2 variants!
Neurodegenerative Disease–Associated Variants in TREM2 Destabilize the Apical Ligand-Binding Region of the Immunoglobulin Domain https://t.co/QrTmnMUAgn

[Alzheimer's Association @alzassociation]

Researchers, join your colleagues at the largest and most influential international global meeting dedicated to advancing dementia science. #AAIC20 is now a virtual event, free of charge. Register today: https://t.co/mpuJl7lhdL.

[🇺🇦 Yuliya Voskobiynyk @Voskobiynyk]

Excited to share @RobersonLabUAB's preprint on AD risk gene BIN1 driving Tau-dependent network hyperexcitability. Thank you to @DayLabUAB and @LLMcMahonNeuro labs for an excellent collaboration!

[Graham Cochrane, MD PhD @grahamdcochrane]

Me seeing similar studies getting published while I sit in isolation listening to Lofi Hip Hop Radio #doubledocs #phdchat

[Rommie Amaro @RommieAmaro]

Full length SARS-CoV-2 spike protein with glycans running in MD shows vastly altered accessibility for small molecules and antibodies (aka #glycotime for the #COVID19 #demogorgon) @LCasalino88 (movie) @zied_gaieb @abbydommer @AmaroLab

[Hunter B Dean @HBDeanMSTP]

@deniswirtz @WUSTL @UCLA @ucsdbe @Cornell @UW @Northeastern @Illinois_Alma @UABNews has switched to a “limited business model” to keep non-essential personnel (including most research personnel) at home. We are also dramatically reducing the sizes of research animal colonies to preserve food and minimize veterinary staff.
https://t.co/X4bu9fnY7f

[Ana Mingorance @CNSdrughunter]

Not knowing a rare disease incidence is a huge problem for patient groups and drug developers.

@LalDennis + colleagues just produced an exceptionally valuable resource: prediction of the incidence of 101 monogenic neurodevelopmental disorders

Pls 🔃

https://t.co/IlIAvqWn2i

[Jeffrey Flier @jflier]

"Everything we do before a pandemic will seem alarmist. Everything we do after a pandemic will seem inadequate."

Michael O. Leavitt, U.S. Secretary of Health and Human Services, 2007.

[Andrea R MD, @andrear9md.bsky.social @AndreaR9Md]

Update. The Cleveland Clinic has developed a COVID 19 test that gives results in 8 hours as opposed to the 2-3 days it takes for the other tests.
They developed the test in NINE days, I repeat nine. Scientists worked 24/7 once the CDC gave them the okay on 3/2.

[Hunter B Dean @HBDeanMSTP]

Scientists: Avoid touching your face to slow the spread of Coronavirus

Trump: Claims to have a “natural ability” for science

Scientists:

[Mark Pepin MD, PhD, FESC @MarkEPepin]

Hilarious description how the USMLE's updated grading policies affect "the medical student stress curve." The 2020 UASOM Best Medicine Show https://t.co/ozwZgvTmwl

[Palli Thordarson @PalliThordarson]

1/25 Part 1 - Why does soap work so well on the SARS-CoV-2, the coronavirus and indeed most viruses? Because it is a self-assembled nanoparticle in which the weakest link is the lipid (fatty) bilayer. A two part thread about soap, viruses and supramolecular chemistry #COVID19

[Dr Kareem Carr @kareem_carr]

As a data scientist, am I the best statistician in my group?
Of course not.
But do I make damn sure the code I write is high quality?
No.
But do I work hard to understand the details of the application more deeply than anybody else on the team?
Also no.

[Hunter B Dean @HBDeanMSTP]

@mattmight Funny, I was just thinking how this sort of thing might be useful when my committee members write letters for my F next month!

[M.K. Sewell-Loftin @MK_SewellLoftin]

The Sewell-Loftin Lab website is up and running! And we are looking to hire graduate students. Please help spread the word to help find recruits who are interested in how biomechanics affect tumor growth.
https://t.co/CabWU1ABem

[Hunter B Dean @HBDeanMSTP]

Another piece of the #Alzheimers puzzle is up on @biorxiv_neursci just in time to talk about at the @UABSOM Neurodegeneration Retreat tomorrow! Thanks to @tombrettlab for leading the way and for wanting to tag on a bit of #compchem!

[Tom Brett @tombrettlab]

Happy to share our latest pre-print, mapping the interaction between TREM2 and ApoE, and demonstrating sTREM2 can inhibit amyloid beta polymerization! Great work @dlkober . Enormous help from @RobersonLabUAB @HBDeanMSTP @JABLab3 !
https://t.co/BDNVz1XjX6

[Nature Portfolio @NaturePortfolio]

Research in Nature reports structures of an orphan G protein-coupled receptor, one with no known endogenous ligand, that can activate itself. https://t.co/eEP81k63je