Harlan Krumholz

Harold H. Hines Jr Professor, Yale Univ; Director, YNHH CORE; Editor-in-Chief, JACC. Working to improve the future for those who follow us...

[Harlan Krumholz @hmkyale]

We are underestimating the downside of our current system when we contemplate change. We need to take some risks to do better. #abimf2013

[JACC Journals @JACCJournals]

Thresholds may guide care, but they cannot capture the context clinical judgment provides. Was a cutoff crossed — or missed — due to measurement uncertainty? How might that threshold shape access to care?

#Thresholds #JACC #CardioX @hmkyale

https://t.co/AD02ivb5RN

[Harlan Krumholz @hmkyale]

@zakkohane @NEJM https://t.co/elDmkJJtyB

[Isaac Kohane @zakkohane]

A good comparator indeed "Compared with what?" @NEJM https://t.co/cRDeITXqgG "As part of this process, investigators should be careful to compare outcomes associated with the use of AI with outcomes in the health care systems we have, rather than the ones we wish we had."

[Harlan Krumholz @hmkyale]

3 in 10 U.S. adults use AI chatbots for health information. Almost 1 in 5 say they cannot afford to see a provider.

@FDA asked how it should judge these systems. My answer starts w/the comparator.

Comments close today. My @JACCJournals Editor’s Page: https://t.co/elDmkJJtyB

[Harlan Krumholz @hmkyale]

We don't ask whether a model touched their prose. We ask authors to own every word.

@JACCJournals parted w/ICMJE & doesn't require disclosure of AI writing help: the rule is unenforceable, biased, & not good for medical communication.

My Editor's Page: https://t.co/veMMajWOzJ

[Harlan Krumholz @hmkyale]

@JXW43 @JACCJournals It depends on the situation. The patient. The scope of the issue. For some, it is still like 1950. For others, it is like 2050. It is a transitional moment.

[Harlan Krumholz @hmkyale]

Search engines gave patients documents. LLMs give them an interpretation and a plan.

The information asymmetry that reinforced the physician's authority is eroding. Where that leaves physicians, in my Editor's Page (free to read): https://t.co/jp4vWtqvT0

@JACCJournals

[JACC Journals @JACCJournals]

Environmental factors are increasingly shaping CV health. What can clinicians do?

Join #JACC at #ESCCongress for Environmental Cardiology: From Exposure to Action, exploring the CV impact of air pollution, wildfire smoke, extreme temps, & more! https://t.co/UevCmEy5RM @hmkyale

[Harlan Krumholz @hmkyale]

My town will vote again, every spring.

The bill is always paid. Our responsibility is to make sure the care it buys is worth what patients and communities must give up.

My Editor's Page in @JACCJournals: https://t.co/ShZh0moerq

[Harlan Krumholz @hmkyale]

This spring, my town voted three times before it could pass a budget.

Guilford, Connecticut. 22,000 people. The debate had the texture those debates always have — schools, roads, fields, what a town owes itself.

Almost no one named the largest force driving it.

[Harlan Krumholz @hmkyale]

The goal should not be less care.

It is less care that does not help, more reliable access to care that does, and greater protection from the financial harm of receiving it.

We should be as literate in a patient's financial exposure as in their ejection fraction.

[Ankeet S. Bhatt, MD, MBA, ScM @ankeetbhatt]

New from the @ACCinTouch:2026 ACC Clinical Guidance on Adult Immunizations as Part of CV Care. Honored to serve as Vice Chair of this effort. Evidence growing that vaccines influence CV risk reduction not just infection prevention. In press @JACCJournals https://t.co/5emXtjAuie

[Circ: PHO @CircOutcomes]

Excited to launch our inaugural editorial team at Circulation: Population Health and Outcomes!

We’ll build on our legacy of outcomes research while embracing the full spectrum of population science–epi, implementation, informatics, econ, and policy.

We hope you will join us!

[Behnood Bikdeli @bbikdeli]

Our study of 💵💵source & online (@altmetric) and academic (citation) impact of CV trials in @JACCJournals: “positive” trials got⬆️attention. For citation, ➕ industry trials were cited ⬆️! We discuss the reasons & implications. @MGBResearchNews 👇

https://t.co/3RQwLOA9QJ

[Ruey Hu, MD, MPH @ruey_hu]

The 🆕 2026 Expert Consensus Decision Pathway on the Management of 🫀HFpEF was published in @JACCJournals @ACCinTouch by Drs @MKIttlesonMD @PanjrathG @SelmaFMohammed @KBreathettMD Januuzzi & Dixon

🔍A deep dive here: 📹https://t.co/kmlvkkQQQn @hmkyale

[Yale School of Management @YaleSOM]

🎙️Health & Veritas podcast: @melanie_matheu, co-founder & chief scientific officer of @LyricBio, joins @thehowie & @hmkyale to talk antibody therapeutics, building biotech companies, and translating complex science for the public. Listen now👇
https://t.co/VWLHGtmTGR