Hailey Edelstein

Scientist @Syenex. Chemical Engineering PhD @TheLeonardLab @NorthwesternU. @Penn alum. Mammalian synthetic biologist engineering cells to make smarter drugs.

[Hailey Edelstein @HaileyEdelstein]

Delighted to share the final version of this paper out now! I led this project with @amparo_cosio during my PhD in @TheLeonardLab to investigate how we could program smart cell therapies to sense and respond to markers of disease—taking inspiration from natural human receptors!

[Josh Leonard @TheLeonardLab]

How can we combine the exquisite function of natural receptors with the programmability of synthetic biology? Check out this exciting new story led by @HaileyEdelstein and @amparo_cosio out today in @nchembio

[Lurie Cancer Center @LurieCancer]

A new study by @LurieCancer member Joshua Leonard, PhD, could ultimately enable the development of safer and more effective treatments for #cancer using ‘smart’ cell therapies." https://t.co/PFE35U0Unw @TheLeonardLab @NUSynBio @NorthwesternEng @HaileyEdelstein @amparo_cosio

[Hailey Edelstein @HaileyEdelstein]

@BashorLab @TheLeonardLab @amparo_cosio @nchembio Thank you!!

[Hailey Edelstein @HaileyEdelstein]

Thank you to @NorthwesternEng for covering our paper! https://t.co/r9n5kyeHFG

[Hailey Edelstein @HaileyEdelstein]

@BlaiseKimmel @amparo_cosio @TheLeonardLab Thank you Blaise!!

[Hailey Edelstein @HaileyEdelstein]

Delighted to share the final version of this paper out now! I led this project with @amparo_cosio during my PhD in @TheLeonardLab to investigate how we could program smart cell therapies to sense and respond to markers of disease—taking inspiration from natural human receptors!

[Josh Leonard @TheLeonardLab]

How can we combine the exquisite function of natural receptors with the programmability of synthetic biology? Check out this exciting new story led by @HaileyEdelstein and @amparo_cosio out today in @nchembio

[Kamat Lab @NehaPKamat]

Excited to share our work @NatureComms on biomembranes, lipid rafts, drug delivery, and extracellular vesicles (EVs). We used lipid-protein interactions to control protein trafficking and improve functional delivery of transcription factors > 50X! https://t.co/bwf2wAws6m (1/8)

[Hailey Edelstein @HaileyEdelstein]

I’m thrilled to finally share this work from the Leonard lab and grateful for a fantastic team, especially my coauthor @amparo_cosio!

[Josh Leonard @TheLeonardLab]

New preprint! Here we introduce NatE MESA – high performing synthetic cytokine receptors that are robust and modular (led by @HaileyEdelstein & @amparo_cosio): https://t.co/5zRc5Cvv9c

[Josh Leonard @TheLeonardLab]

Red blood cells have some wildly cool capabilities – what if we could engineer them to work as living diagnostics? Check out this exciting first step (led by @TaylorDolberg & @taylor_gunnels): https://t.co/fyUlx7xgPK

[Josh Leonard @TheLeonardLab]

VERY excited to welcome this paper out in @natBME where we introduce the GEMINI platform for engineering multifunctional extracellular vesicles as versatile, programmable, biological delivery vehicles
https://t.co/EqF6pTqyQp

[Josh Leonard @TheLeonardLab]

What a fun collaboration with @NehaPKamat & @UWproteindesign led by @jperuzz & @taylor_gunnels - dig in for some fascinating EV science and useful EV bioengineering tools that we are thrilled to share

[Kamat Lab @NehaPKamat]

Have you ever wondered how to improve loading of protein cargo into extracellular vesicles? Excited to share our latest work exploring how lipid-protein interactions may be leveraged to direct proteins into extracellular vesicles! https://t.co/L4IWDRFv3i 🧵 1/6

[Dr. Tara Deans (she/her) @genegirl007]

Hello darkness my old friend...Have you ever had your transgene or synthetic gene circuit silence? Check out this awesome collaborative review by many leaders in mammalian synbio. https://t.co/flQLjhJxFw

[syenex @syenex]

We’re thrilled to be selected by @abbvie for their 2022 AIM award! Great work team! @TheLeonardLab @jdrosanelli @DevinStranford @HaileyEdelstein

[Josh Leonard @TheLeonardLab]

I’m thrilled to introduce a story that has been many years in the making – the GEMINI platform for engineering multifunctional extracellular vesicles as versatile, programmable, biological delivery vehicles
https://t.co/vPkGl7VQmX

[Josh Leonard @TheLeonardLab]

Check out a fun new perspective on super-cool recent work by @ElowitzLab, Richard Murray and team in @GENBiotechJrnl (with @HaileyEdelstein and @_gauribora ) https://t.co/RB3lYQEmIh

[Taylor Gunnels @taylor_gunnels]

Happy to share that our study on engineering nanoscale decoys to fight COVID-19 is now published! A big thank you to the team for your hard work, advice, & mentorship! (@TheLeonardLab @NehaPKamat @DevinStranford @roxi_mitrut )

[Josh Leonard @TheLeonardLab]

Very psyched to see this paper out in the world - it is the review we wish existed! Hope this is as much fun to read as it was to write with @LeonardoMorsut, @HaileyEdelstein, and @JanvieManhas with great input from Terry Sheppard from @nchembio

[Hailey Edelstein @HaileyEdelstein]

I’m so proud to see this review finally out! The synthetic receptor space is evolving quickly and capturing that development here was all around fun! Thanks to my co-authors for all of the brainstorms and teamwork. It’s been a blast! @JanvieManhas @TheLeonardLab @LeonardoMorsut

[Leonardo Morsut @LeonardoMorsut]

Synthetic receptors have come a long way! We’re very excited to share this comprehensive review of the origins, development, and state-of-the art of this field, co-written with @TheLeonardLab in @nchembio

https://t.co/u3AKMXxjdF

[Josh Leonard @TheLeonardLab]

Happy to share our new review on the power of using process control concepts to understand and build genetic programs in mammalian cells by @dray_kate @HaileyEdelstein @kdreyer96 @NorthwesternEng @NUSynBio https://t.co/z0a3X1awi7

[Hailey Edelstein @HaileyEdelstein]

@PatrickSDonahue @tera_levin Can’t forget the obligatory hand lotion for the cold Chicago winters! I think our lab has more than a dozen varieties across all our desks at this point 🥶