HaitinLab

Located at @TelAvivUni. We study the molecular basis of information transfer within ion channels and prenyltransferases.

[Dor Salomon @DrDorSalomon]

1/New paper🚨 combining #T6SS + #antiphage
We previously identified an antiphage system, GAPS4, but we didn’t know what it targets or what triggers it. Chasing that last question took us somewhere we didn’t expect: GAPS4 is a sentinel of DNA integrity.
https://t.co/m7qoEhPTFH

[HaitinLab @HaitinLab]

Welcome to our lab! @TAUMedFaculty

[EMBL @embl]

Scientists have determined the highest-resolution protein structure obtained to date.

Using advanced X-ray crystallography at EMBL Hamburg's P14 beamline, the team solved the structure of an archaeal protein at an astonishing 0.43 Ångström resolution.

https://t.co/loVtdOW4U8

[HaitinLab @HaitinLab]

#DEE #DHDDS
@CureDhdds @TelAvivUni @TAUMedFaculty @tasmc1

[HaitinLab @HaitinLab]

Great to be part of this team! 🎉🍾
Mice with the mono-allelic p.R37H Dhdds variant show aberrant glycosylation and interneuron deficits https://t.co/4smZjBGfhQ

[HaitinLab @HaitinLab]

🚨One probe. 🧪One assay. 👯Two answers. Our new fluorescent platform identifies prenylation inhibitors and reveals how they work, streamlining both screening and mechanistic studies. https://t.co/55UZm1sXHT @TAUMedFaculty @tasmc1 #MedicinalChemistry #DrugDiscovery

[HaitinLab @HaitinLab]

🚨One probe. 🧪One assay. 👯Two answers. Our new fluorescent platform identifies prenylation inhibitors and reveals how they work, streamlining both screening and mechanistic studies. https://t.co/55UZm1sXHT @TAUMedFaculty @tasmc1 #MedicinalChemistry #DrugDiscovery

[HaitinLab @HaitinLab]

@LindorffLarsen Fascinating, thank you!

[HaitinLab @HaitinLab]

Nice! #bettertogether?
https://t.co/DmARtp8VtR

[Kresten Lindorff-Larsen @LindorffLarsen]

Time-resolved experiments are powerful, but difficult to interpret ⏱️💃

In "A Bayesian Approach to Interpret Time-Resolved Experiments Using Molecular Simulations" Carl and Simone developed an approach to use MD to interpret time-resolved experiments

https://t.co/UNbwtQXQ5p

[HaitinLab @HaitinLab]

@inna_slutsky @ProteinSociety @TAUMedFaculty Thanks Inna!

[HaitinLab @HaitinLab]

Excited to share our new paper in @ProteinSociety 🎉
We combine #BioEmu and SAXS ensemble optimization to characterize protein conformational heterogeneity, bridging AI-generated ensembles and experimental data.
https://t.co/DmARtp8VtR

#SAXS #MachineLearning
@TAUMedFaculty

[HaitinLab @HaitinLab]

@MosheParnas @ProteinSociety @TAUMedFaculty Thanks Shiko!

[HaitinLab @HaitinLab]

Excited to share our new paper in @ProteinSociety 🎉
We combine #BioEmu and SAXS ensemble optimization to characterize protein conformational heterogeneity, bridging AI-generated ensembles and experimental data.
https://t.co/DmARtp8VtR

#SAXS #MachineLearning
@TAUMedFaculty

[HaitinLab @HaitinLab]

@LabRubinstein Congrats Moran and team!!❤️😘🍾🥂 @TAUMedFaculty @of_sagol @TelAvivUni

[HaitinLab @HaitinLab]

@peterslab1 Truly a privilege to work with you and your group, and we are excited for what comes next!

[HaitinLab @HaitinLab]

Grateful to our fantastic collaborators @peterslab1 and @AlbGiacomello on this journey! @TAUMedFaculty @of_sagol @SouraskyMedCtr #Biochemistry #StructuralBiology

[HaitinLab @HaitinLab]

🚨It's finally out!🥂 | A few years after solving the structure of human cis-PT, we now tackle its dynamics in @NatureComms, revealing that a conserved interfacial loop serves as an allosteric hub, communicating with the active site to regulate catalysis. https://t.co/fZRY0UHjVg

[Dor Salomon @DrDorSalomon]

🚨 Happy to share our new preprint in which we explore different layers of the phage-bacteria arms race.
The highlight: phage homing endonucleases attenuate bacterial defenses 🤯
A 🧵... (1/7)
#bacteriology #antiphage #T6SS
@TelAvivUni @TAUMedFaculty
https://t.co/FJUg8Cyr6h

[Dor Salomon @DrDorSalomon]

A huge Thank You to all the collaborators who contributed to this fun project @UdiQimron @HaitinLab @BursteinLab @canareck_, and congrats to the first author @tridib_mahata !

An open question remains - where will this be published? 😏