Hieter Lab

Our lab works on understanding genome stability and its role in cancer, using model systems (yeast, worms, & cancer cells). Find us in Michael Smith Labs @ UBC.

[Hieter Lab @HieterLab]

Our latest work is now out in DNA Repair. Synthetic cytotoxicity profiling of cohesin mutants highlights recombi... https://t.co/YszFT0kolw @ubcmsl

[Hieter Lab @HieterLab]

Our collaboration with @StirlingLab now out at PNAS. Deep structure–function analysis of the endonuclease Mus81 with dominant mutational scanning | PNAS https://t.co/8UX2DcMToh

[Hieter Lab @HieterLab]

Excited to see this interesting story get published. @ubcmsl Distribution of haploid chromosomes into separate nuclei in two pathogenic fungi | Science https://t.co/22YvlpxniS

[Hieter Lab @HieterLab]

New SL paper from the Hieter and Stirling labs @stirlinglab . Mapping of DDX11 genetic interactions defines sister chromatid cohesion as the major dependency https://t.co/525YuE7V35

[Michael Smith Labs @ubcmsl]

.@ubcpharmacy professor Dr. Corey Nislow & Dr. @philhieter of MSL's @HieterLab discuss yeast research from NASA’s #Artemis 1 lunar mission.

UBC scientist’s ‘mutant yeast’ from space could help future astronauts, cancer patients | https://t.co/iMhap3rdzn https://t.co/EwDn4WCeEw

[🔬 R-loop @R_loop_papers]

RAD18 opposes transcription-associated genome instability through FANCD2 recruitment https://t.co/aRlFwNNwFC

[Société de recherche sur le cancer @SRC_CRS]

ALL-TIME RECORD | We are proud to award 90  new research grants valued at $10.8 million as part of our annual competition. The grants are awarded to some of the most promising cancer research projects in Canada. 🎉🔬

👉 https://t.co/BUq4DzlKFd

#CancerResearchSociety

[Genetics Society of America @GeneticsGSA]

#GENETICS and #G3journal are pleased to announce a Call for Papers on Genetic Models of Rare Diseases. This new series is led by Brenda Andrews, Hugo Bellen, @dougfowler42, and @HieterLab; submissions for the launch issue are due November 14! #rarediseases https://t.co/57VUMJlwad

[Science in Vancouver @ScienceVancity]

🎉 Congratulations to everyone who received awards in August! ☀️

Dr. Philip Hieter (@HieterLab) received a @CIHR_IRSC grant to expand the impact and reach of the Canadian ‘#RareDiseases: Models and Mechanisms’ Network.

See more award winners:
https://t.co/E05S8wRGQv

[Hieter Lab @HieterLab]

The Hieter Lab is at #yeast22. Anthony Oppedisano is presenting "Mutational Scanning to find Synthetic Lethal interactions with the repair endonuclease Mus81" on Friday evening. Poster 177B.

[Shawn Shortill @ShawnShortill]

I’m very excited to share that my PhD work is now published @eLife! We used a combination of genetics, cell biology and biochemistry to identify a new endosomal complex in yeast, which we named VINE 🌿 Early access here: https://t.co/BUF7s3xYjL. (1/n).

[Michael Smith Labs @ubcmsl]

Congratulations to Dr. Leanne Amitzi on her graduation today! 🎓 Dr. Amitzi, of the @HieterLab, has successfully earned her Doctor of Philosophy (#PhD) in Medical #Genetics ! 🎉🧬

[Michael Smith Labs @ubcmsl]

Join us today for our seminar with Dr. Maitreya Dunham (@DunhamLab) from @uwgenome on "High throughput human genetics in yeast".

April 13th, 3-4pm, PST
Host: Dr. Phil Hieter (@HieterLab)
Event details & zoom registration:
https://t.co/buz9ZapmsA

[Science in Vancouver @ScienceVancity]

Drs. Peter Stirling (@pcstirling), David Huntsman, & Philip Hieter (@HieterLab) received an @OvarianCanada/@SRC_CRS grant to develop drugs that will convert proteins that normally repair DNA into toxic agents that selectively kill #OvarianCancer cells. 🧬

https://t.co/0KiFwu08ZM

[Hieter Lab @HieterLab]

@MEDGGSA @pcstirling Congratulations Peter @pcstirling.

[Hieter Lab @HieterLab]

New from us in collaboration with the Moffat Lab at
@DonnellyCentre. Great work by Melanie Bailey using CRISPR screens to find STAG2 dependencies in 3 different cell lines.

[LifeScienceAlliance @LSAjournal]

@HieterLab uses CRISPR-Cas9 screening to explore the context-dependency of genetic interactions of the cancer-mutated cohesin gene STAG2 in three different cellular backgrounds @HieterLab @ubcmsl

https://t.co/9IRmqVUyTe

[Karen I. Lange @KarenL_PhD]

Great review of disease modelling and drug discovery in worms! Really highlights how versatile worms are.

https://t.co/AHm4laZ3b1

[Hieter Lab @HieterLab]

We got the band back together for this Gpn2 RNA polymerase biogenesis story. Collaboration with @StirlingLab
https://t.co/QnMe74KWsM

[Canadian Medical Hall Fame @CdnMedHallFame]

#CMHFLaureate @mmarra0630 head of the Personalized Oncogenomics project @BCCancer, using information derived from thousands of individual #cancer genomes & transcriptomes to identify promising therapeutic targets in individual patients https://t.co/fFiwj3XapR