Ian M. Oh (오규식)

SRA @ Grinberg Lab, UCSF Neurology | B.A. Molecular/Cell Biology & Data Science, Cal '21 | Researcher | Photographer | Maker | (He/They) | All views my own.

[Ian M. Oh (오규식) @IanOh_]

This is an amazing opportunity to lead the frontier in illuminating changes to circadian physiology in the context of Alzheimer’s disease and related dementias!

[Lea T. Grinberg, M.D, Ph.D @grinberg_t]

PLEASE HELP SHARING - LOOKING FOR POST-DOCS to study the basis of sleep and circadian dysfunction in Alzheimer's and related diseases. https://t.co/62FNcgmf1e @ISTAART @NSS_PIA @ResearchSleep @SleepPIA

[Ian M. Oh (오규식) @IanOh_]

Many thanks to Zoe @SenJoshBecker for meeting with my @californiaalz advocate team to discuss proposals to improve state support for research and #Care4Alz. We hope to continue to lead the nation in Alzheimer’s prevention, diagnostics, treatment, and care! #ENDALZ

[Ian M. Oh (오규식) @IanOh_]

A huge thank you to Savanah @AsmDianePapan for meeting with my @californiaalz advocate team to discuss proposals to improve research and #Care4Alz in CA that will help us maintain our position as national leaders in prevention, diagnostics, treatments, and care! #ENDALZ

[Ian M. Oh (오규식) @IanOh_]

My power team for the day for meeting with the California state legislature to increase support for Alzheimer’s care and research! @AlzAdvocateCA #EndAlz #Care4Alz

[Prof. Melissa E. Murray 📸🔬 @DrNeuroChic]

And now for a unique version of #FluorescenceFriday with a little addition of showcasing the importance of protecting our beautiful brains. Epic photo before our ziplining adventure @HAIconference

Left to right: yours truly, @DrMariaALZ, Reisa Sperling, @grinberg_t, @hckolb

[Yue Leng @YueLengsleep]

Very excited to share our new findings on REM sleep latency and AD biomarkers🧠 - REM #sleep is more than a #DREAM! Special thanks to @Yunfeng_Zheng for making this fun and productive collaboration happen! @UCSFHospitals @UCSFPsychiatry @UCSFmac @alzassociation @SleepPIA

[Ian M. Oh (오규식) @IanOh_]

Excellent example of our teamwork and problem solving spirit!

[Lea T. Grinberg, M.D, Ph.D @grinberg_t]

Amazing evening celebrating a year of achievements w/ the lab! We crushed 3 escape rooms with 0 to 1 clue—proof we’re pros at solving complex puzzles. We’ve earned every bit of our NIH awards to keep cracking the code of dementia. @GrinbergLabUCSF @UCSFmac @GBHI_Fellows @NSS_PIA

[Ian M. Oh (오규식) @IanOh_]

Same! Come and find me on Bluesky!

https://t.co/AkxLjCdUTf

[Lea T. Grinberg, M.D, Ph.D @grinberg_t]

Excited to share that I've joined Bluesky! You can now find me at @leatgrinberg.bsky.social. Looking forward to continuing to share and discuss science with you all there. See you on Bluesky! 🌟"

[Lea T. Grinberg, M.D, Ph.D @grinberg_t]

SV2A PET tracers may help detecting synaptic loss in vivo, but a map of SV2A in human brain tissue is missing. We mapped SV2A & synaptophysin in #alzheimer & others to enhance interpretation of PET studies. https://t.co/fhuA3ctebV @UCSFmac @GrinbergLab @HAIconference @ISTAART

[Neus Falgàs @NeusFalgas]

Grateful to the @Alz_ClinicBCN team and especially to these great panel of women research scientist for leading our latest article #womeninSTEM 👩‍🔬🧠🥼@Andrea_delvalg @agnesperezmi @beaboschc @sanchezvaller @grinberg_t @hospitalclinic @UCSFmac @GBHI_Fellows @awarepia

[Gowoon Son, PhD @gowoon_son]

Poster #120 The human brain clock in neuromodulatory subcortical nuclei @NSS_PIA is vulnerable to tau pathology in the absence of amyloid, examined by Digital Spatial Profiler @nanostringtech @GrinbergLabUCSF @grinberg_t @UCSFmac see more on grinberg lab #AAIC24 below. @SleepPIA

[Lea T. Grinberg, M.D, Ph.D @grinberg_t]

@NeusFalgas has lead an effort to put together a unique longitudinal cohort, possible because of @hospitalclinic @sanchezvaller which undertake LC & hypothalamus imaging and get neurotransmitters measured. on the way to map @NSS_PIA in #alzheimer in vivo. Watch her #AAIC24

[Lea T. Grinberg, M.D, Ph.D @grinberg_t]

Excited to share our latest on #Tauopathies! 🧠 Using iPSC der-neurons with MAPT V337M mutations and novel antibodies, we showed caspase-6 cleaved tau plays a neurotoxic role. Caspase inhibitors prevented this toxicity, New therapeutic avenues? https://t.co/xnOztpQEPy @UCSFmac

[Lea T. Grinberg, M.D, Ph.D @grinberg_t]

These studies are real team science. Grateful to @RCFNeuro where @MichelleArkin and I met, seeding funds from @UCSF & @alzassociation for D13 and D402 antibodies, and @NIHAging funds for cell development with @karchlab, Sally Temple, and David Butler. @GrinbergLabUCSF

[Lea T. Grinberg, M.D, Ph.D @grinberg_t]

The real star here is Panos Theofilas, who led these studies. If you're attending #AAIC24, check out @LiaraR_'s poster on Monday (#828) to see the results from our homebrew @QuanterixSimoa assay, developed to detect D13-tau in CSF. 🌟🔬 #Neuroscience #Research #Alzheimers

[Lea T. Grinberg, M.D, Ph.D @grinberg_t]

@AbhijitSatpati will present #aaic24 novel data showing how a pattern of distinctive vulnerability of #sleep-promoting LHA neurons in #alzheimer variants tracks well with clinical sleep profile @GrinbergLabUCSF @NSS_PIA

[Lea T. Grinberg, M.D, Ph.D @grinberg_t]

Celebrating our amazing lab members and their achievements is even better on a sunny day! ☀️👏 @GrinbergLabUCSF @IanOh_ @gowoon_son @AbhijitSatpati @YhJonathanChen @UCSFmac

[Ian M. Oh (오규식) @IanOh_]

@YueLengsleep @SpeakerPelosi Amazing, congrats!! 🎉

[Ian M. Oh (오규식) @IanOh_]

@NeusFalgas @NIHAging @alzassociation @hospitalclinic @GBHI_Fellows Felicidades Neus!

[Grinberg Lab UCSF @GrinbergLabUCSF]

Celebrating one of our very accomplished SRA students, Yumi Yang, before she embarks on her new academic journey at Yale. Go for it Yumi! @grinberg_t