Icculus

#LongCovid since March 2020. If you're not fighting injustice you're most likely benefiting from it.

[Icculus @Icculus27]

More evidence for viral persistence

[Amy Proal, PhD @microbeminded2]

I am excited to share our new position paper on #SARS-CoV-2 reservoir (viral persistence) in Long COVID or post-acute sequelae of COVID (PASC): https://t.co/cxx7NjuGrC

[Icculus @Icculus27]

@sebdave23 Please hang on. I’m there regularly too. 3+ years into this and getting worse but there are still things I haven’t tried. Don’t give up yet.

[Icculus @Icculus27]

More evidence of viral persistence. Where are the treatments?

[Michael Peluso, MD @MichaelPelusoMD]

Our new #UCSF preprint showing prolonged tissue-level immune activation and gut viral persistence for up to 2 years post-COVID. Does COVID-19 induce a new immunologic set-point and how is this related to PASC/Long COVID?

https://t.co/nZRVkAy8MZ

[Icculus @Icculus27]

@TheNicotineTest Yes, didn’t do anything for me

[Icculus @Icculus27]

It. is. viral. persistence. give. us. fucking. treatments. now.

[Hannah Davis @ahandvanish]

Wow, this new paper is a huge deal! T cell activation & viral RNA persistence were found up to 2 years post acute infection in #LongCovid patients.

Patients with T cell activation in the spinal cord and gut wall were more likely to have Long Covid. 1/

https://t.co/byQgZJGVNG

[Icculus @Icculus27]

@sebdave23 How many days are you planning on doing?

[Icculus @Icculus27]

Once again Ed Yong nails it. So grateful to have people like this fighting for us. Thank you Ed.

[Ed Yong is not here @edyong209]

🛑I wrote about what “fatigue” really means for people with long COVID and ME/CFS, and why this profoundly debilitating symptom is so often misunderstood and trivialized.

(This piece also covers PEM.) 1/

https://t.co/oFWb6Flyh0

[Icculus @Icculus27]

@sarahnadav 3 weeks ago

[Icculus @Icculus27]

3 weeks ago I had #longcovid, but I could still go grocery shopping, read bedtime stories to my daughter, socialize with my friends, have sex with my wife. I had one HELP Apheresis treatment and can't do any of those things now. My quality of life went from shitty to nonexistent.

[Icculus @Icculus27]

@jason_isaia That's brutal, sorry you're dealing with this too.

[Icculus @Icculus27]

@BiologistBunk @AmandaB55744931 No diet changes

[Icculus @Icculus27]

2 weeks ago I was functioning at 70% working full time and taking care of a toddler. I received one HELP Apheresis treatment and I’m now bedbound. I’m terrified. I cannot live like this. My wife lost her husband and my daughter lost her father. #longcovid

[Icculus @Icculus27]

@AmandaB55744931 @BiologistBunk Thank you, it has been a nightmare that I keep hoping to wake up from

[Icculus @Icculus27]

@AmandaB55744931 @BiologistBunk It has been up and down, but mostly down. Able to make it to my couch some days, other days can't get out of bed.

[Icculus @Icculus27]

@BiologistBunk @AmandaB55744931 It's been 3 weeks now and still nowhere near back to my baseline. I hope you're right that this is transient.

[Icculus @Icculus27]

@HeliRetzek @souryadash 3 different anticoagulants

[Icculus @Icculus27]

@goodhewc Yes confirmed microclots

[Icculus @Icculus27]

@dbdugger Was that with truvada? What are your thoughts on sofosbuvir?

[Icculus @Icculus27]

@Alexand39060188 So sorry to hear that. Did you get progressively worse after each treatment?

[Icculus @Icculus27]

@IleanaNaish Yes everyone at the clinic was great - it was in Zurich.