isb_bonn

We are interested in structure-function relationships of biological macromolecules.

[Radek Nowak @RPNowak]

Was great to contribute to this story together with @JanGerhartz @dpienkowska9 Ina Dressel & Thomas Geiger from the lab. #CRBN #Interactome #GLUES @CellChemBiol @EnamineGermany @iDikic2 @merckgroup @ibetportugal @MPIbp
Animation credit @proxidrugs
Paper: https://t.co/2Qq3xUCCDe

[isb_bonn @IsbBonn]

Congratulations @NielsSchneberg1 what a way to finish a PhD! With @sc_binder @PhilippHendr @MartinPeter91 @PAKoenig @GavinHThomas @SMenzel @PAKoenig @GavinHThomas & Gregor Hageleuken! #Nanobodies #TRAP.

[Niels Schneberger @NielsSchneberg1]

We found a #VHH antibody that allosterically inhibits sialic acid binding by the #TRAP transporter #SBP VcSiaP.
Thanks to the team @PhilippHendr @MartinPeter91 @sc_binder @PAKoenig @SMenzel @ @GavinHThomas @GHagelueken
Read the full story here:

https://t.co/79K8MMwhjt

[Niels Schneberger @NielsSchneberg1]

We found a #VHH antibody that allosterically inhibits sialic acid binding by the #TRAP transporter #SBP VcSiaP.
Thanks to the team @PhilippHendr @MartinPeter91 @sc_binder @PAKoenig @SMenzel @ @GavinHThomas @GHagelueken
Read the full story here:

https://t.co/79K8MMwhjt

[Radek Nowak @RPNowak]

Had to get one for the lab. #Falcon your falcon! Printed by @gha14
Instructions:
https://t.co/3hAWNEIxkk

[Radek Nowak @RPNowak]

We are hiring! Looking for a #postdoc to join the team in the Nowak Lab to focus on chemical biology in cells and recombinant systems. Excited about protein degradation, small molecule proximity? get in touch!
#TPD #InducedProximity #ChemicalBiology
https://t.co/SYxOT8RwCi

[isb_bonn @IsbBonn]

Congratulations to @JanGerhartz for this nice piece! Go go Jan! #KEAP1 #InducedProximity

[Jan Gerhartz @JanGerhartz]

It was a lot of fun to writhe the preview perspective article: “A Double Whammy for KEAP1”.
Discover the bivalent mechanism affecting KEAP1 and their implications for future small molecules.
#FirstPaperFromTheLab #Science #KEAP1 #Biology #NewPublication
https://t.co/nNQIepjyCV

[Jan Gerhartz @JanGerhartz]

It was a lot of fun to writhe the preview perspective article: “A Double Whammy for KEAP1”.
Discover the bivalent mechanism affecting KEAP1 and their implications for future small molecules.
#FirstPaperFromTheLab #Science #KEAP1 #Biology #NewPublication
https://t.co/nNQIepjyCV

[Radek Nowak @RPNowak]

We are #hiring! We have an open #postdoctoral position in my group with the focus on structural biology #cryoEM and X-ray crystallography of new #E3 ligases as well as #molecularglue complexes. @UniBonn @IsbBonn
https://t.co/SYxOT8RwCi Please RT!

[isb_bonn @IsbBonn]

Welcome Ina and Dominika!

[Radek Nowak @RPNowak]

Great to have Dominika Pieńkowska and Ina Dressel join the Nowak lab! Dominika started her Master's project with us and Ina joined as a lab manager.
BelatedTwitter welcome Dominika and Ina! @JanGerhartz #GoTeam #TPD #NewPI @UniBonn @UniklinikBonn @IsbBonn
https://t.co/SYxOT8QYMK

[Radek Nowak @RPNowak]

Great to have Dominika Pieńkowska and Ina Dressel join the Nowak lab! Dominika started her Master's project with us and Ina joined as a lab manager.
BelatedTwitter welcome Dominika and Ina! @JanGerhartz #GoTeam #TPD #NewPI @UniBonn @UniklinikBonn @IsbBonn
https://t.co/SYxOT8QYMK

[Radek Nowak @RPNowak]

Targeted protein #degradation: from mechanisms to #clinic. New molecular mechanisms can rapidly be translated - we can learn so much from nature.
Great to be able to share this piece with @jonathanMtsai Ben Ebert and Eric Fischer @fischerlab1. #TPD https://t.co/Czk3aeQ7td

[isb_bonn @IsbBonn]

Huge congrats to our amazing colleague @IsabellJamitzky for winning the GBM Master Thesis Award! Absolutely deserved for her incredible work on investigating Gasdermin D.

She wrote a small post about her journey: https://t.co/3Jl0aTlPKm

Thanks!! @Buelow_Lab @FEBSnews @GBM_eV

[isb_bonn @IsbBonn]

Big congratulations to our dynamic trio @PhilippHendr @MaxSticks7 @NielsSchneberg1 for their outstanding talks and thanks for the following insightful discussions with the audience! 🎉👏 #DGK2024

[isb_bonn @IsbBonn]

Congratulations to Dr. @InesKalt for successfully defending her PhD thesis! 🎓
We wish you all the best for your journey in Oxford.
We will miss you in our lab and especially in the CDK family.🧬

[isb_bonn @IsbBonn]

We are happy to announce that our team member Dominic Ferber has received a doctoral scholarship from the @studienstiftung! Great support for his PhD research. Congratulations!

[isb_bonn @IsbBonn]

@jbiolchem Exciting research from our lab and congrats to @MaxSticks7 and colleagues for this great publication!

[Radek Nowak @RPNowak]

NEWS! I'm excited to share that I'm joining @IsbBonn @UniklinikBonn @UniBonn @ImmunoSens as a professor to start my LAB! We are open for business and #hiring for #postdoc #tech positions! #NewPI #MoveToGermany #UniBonn #TPD #InducedProximity Please share! https://t.co/91TSBWYDTk

[Radek Nowak @RPNowak]

Excited about #TPD and #InducedProximity? So are we, and we are recruiting! #postdoc #technician
#NowakLab #Germany @UniBonn @UniklinikBonn @ImmunoSens Please DM or reach us on https://t.co/SYxOT8QYMK

[Journal of Biological Chemistry @jbiolchem]

New in JBC press: "Scientists' results provide the basis for a rational improvement of SR-4835 towards Cdk12 inhibition and a gain in selectivity over other transcription regulating CDKs."
Learn more:
https://t.co/90sbgwKrS8

[Dr Róisín McManus @Roisin_McManus_]

📢 We are #hiring!

🥼 We’re looking for a #postdoc to work on an exciting, collaborative project between myself & @eickelatz at the @IIIBonn and @DZNE_en in Bonn, Germany!

#job @ImmunoSens @UniklinikBonn

https://t.co/8THSjXwNMG