Julia Lyudchik

Bioimage analysis and scientific visualization 🔬💻🖌, PhD @ISTAustria

[Julia Lyudchik @JLyudchik]

Our Light-microscopy based #connectomics project is finally out! 🧠Amazing collaboration (and another chance for me to create fancy 3D renderings 😏)
Shout out to @RTMojtaba , Michal Januszewski, @stardazed0 and the whole @DanzlLab for making it happen!
https://t.co/s0yda78aUM

[Julia Lyudchik @JLyudchik]

Glad to be part of this amazing work! 🌈🧠🔬

[Andrew Payne @Andrew_C_Payne]

@E11BIO is excited to unveil PRISM technology for mapping brain wiring with simple light microscopes. Today, brain mapping in humans and other mammals is bottlenecked by accurate neuron tracing. PRISM uses molecular ID codes and AI to help neurons trace themselves. We discovered a new cell barcoding approach exceeding comparable methods by more than 750x. This is the heart of PRISM. We integrated this capability with microscopy and AI image analysis to automatically trace neurons at high resolution and annotate them with molecular features.

This is a key advance towards economically viable brain mapping - 95% of costs stem from neuron tracing. It is also an important step towards democratizing neuron tracing for everyday neuroscience. Solving these problems is critical for curing brain disorders, building safer and human-like AI, and even simulating brain function.

In our first pilot study, we acquired a unique dataset in mouse hippocampus. Barcodes improved the accuracy of tracing genetically labelled neurons by 8x – with a clear path to 100x or more. They also permit tracing across spatial gaps – essential for mitigating tissue section loss in whole-brain scaling. Using molecular annotation, we uncover an intriguing feature of synaptic organization, demonstrating how PRISM can be used for systematic discovery 🧵

[E11 Bio @E11BIO]

E11 Bio is launching Volara: an open-source Python library for block-wise processing of large volumetric microscopy datasets!

Built on top of Daisy (a lightweight framework from the Funke Lab at Janelia), Volara features block-wise task abstractions, making scalable image processing more accessible, robust, and repeatable. Developed for neuron segmentation, Volara includes tools for extracting segmentations from affinity graphs and is easily extendable for other image processing pipelines beyond connectomics.

Read more: https://t.co/4doh6G5CDL

[nature @Nature]

A fluorescence-microscopy method for tracing neuronal connections in the brain could make connectomics studies more widely accessible for neuroscientists

https://t.co/5Z5rkSwhBH

[Google AI @GoogleAI]

Today, in collaboration w/ colleagues at the Institute of Science and Technology Austria (ISTA), we report the first-ever method for using light microscopy to comprehensively map all the neurons & their connections in a block of mouse brain tissue. More →https://t.co/i8wWRgPidU

[Andrew Payne @Andrew_C_Payne]

E11 Bio is excited to share a major step towards brain mapping at 100x lower cost, making whole-brain connectomics at human & mouse scale feasible (🧠→🔬→💻). Critical for curing brain disorders, building human-like AI systems, and even simulating human brains. 1/N 🧵

[Julia Lyudchik @JLyudchik]

Jumping into #SciartSeptember with some screenshots of the introductory movie I made for my PhD defense presentation🧠

Sometimes a covid-related sick leave can be quite productive:)
#blender3d #b3d

[Julia Lyudchik @JLyudchik]

@wiebkejahr Thank you so much!!!

[Julia Lyudchik @JLyudchik]

Dr. Julia it is💅
One small step for mankind, one giant leap for me😁

[Julia Lyudchik @JLyudchik]

@juliammichalska @Nagudelo715 Thank you!! Another Dr. Julia😁

[Julia Lyudchik @JLyudchik]

@gomez_mariscal Thanks!!

[Julia Lyudchik @JLyudchik]

@stardazed0 Thank you so much!

[Julia Lyudchik @JLyudchik]

@jakobtroidl Thank you!!

[Julia Lyudchik @JLyudchik]

@PhotonPhilipp Thank you!!!

[Julia Lyudchik @JLyudchik]

@ScienceSven Thank you so much!

[Julia Lyudchik @JLyudchik]

@Nagudelo715 The way you've guessed the color of my shoes is legendary🥰🥰🥰

[Young Scientists Symposium @yss_ista]

🚀Exciting News! Registration is NOW OPEN for our upcoming Young Scientists Symposium 2024! 🔬✨

🗓️Date: 6 November 2024 📍Location: @ISTAustria
You can register to present a poster or give a talk! https://t.co/xVQH4Ubn2Z #YSS2024

[preLights @preLights]

LICONN uses molecular labelling + deep learning to reconstruct brain circuitry, bridging the gap between EM & molecular specificity. 🔬

@CemreCoskun_ highlights a preprint from @RTMojtaba, @JLyudchik, others in the @JGDanzl lab & @stardazed0

#preLight ⬇️ https://t.co/JOVyHqAVgG

[Julia Lyudchik @JLyudchik]

@juliammichalska @PhotonPhilipp @ISTAustria @ScienceMagazine 🤩🥰

[Julia Lyudchik @JLyudchik]

@jakobtroidl @RTMojtaba @stardazed0 @DanzlLab Thank you!

[Julia Lyudchik @JLyudchik]

Our Light-microscopy based #connectomics project is finally out! 🧠Amazing collaboration (and another chance for me to create fancy 3D renderings 😏)
Shout out to @RTMojtaba , Michal Januszewski, @stardazed0 and the whole @DanzlLab for making it happen!
https://t.co/s0yda78aUM