Jason Meaux

Robotics, Writing about SSMs Hosting the PyTorch ATX meetup in Austin

[Jason Meaux @JasonMeaux]

Next year @corl_conf will be held in Austin, TX!

November 9-12, 2026

[Kyle🤖🚀🦭 @KyleMorgenstein]

Chat if people come up to you the day after to talk about your karaoke performance of Thrift Shop is that good or bad

Anyways, had a blast at CoRL/Humanoids. Next year in Austin!! 🤠

[Alex Rives @alexrives]

Together with UC Berkeley we are announcing the laser phase plate - a breakthrough in atomic resolution imaging. This is the brightest continuous wave laser in the world, 100 million times the intensity of the surface of the sun.

Phase contrast plays an important role in microscopy, but it was thought close to impossible for electron microscopy, where it would require interfering with an electron beam. Holger Mueller and Robert Glaeser proposed exactly this using a standing wave laser. It has taken over 15 years to make this a reality. Biohub partnered with UC Berkeley and Mueller to support this work and to engineer and build the technology.

Contrast has been the critical barrier to achieving atomic resolution imaging of the cell. In cryo-electron tomography, a cellular imaging technology that uses electron microscopy, the low contrast makes it impossible to resolve anything but the largest proteins within their cellular context. The laser phase plate removes that barrier.

With advances in AI this breakthrough in contrast will start to open up a new frontier in structural biology, that will allow us to see the molecular machines of the cell, and how they assemble into far more complex and dynamic systems, and understand how they work.

[York Kang @york1to]

@yacineMTB

[NewLimit @newlimit]

Following breakthrough results, we’re bringing longevity medicine to human trials.

We’ve raised a $435M Series C led by @foundersfund to make it happen.

Reprogramming cell age has the potential to create more healthy years for everyone. We're closer than ever to realizing it.

[Parth Ingle @parthingle_x]

https://t.co/Hb1FQPTIPz

[Derek Thompson @DKThomp]

This has quietly been a miracle month in medicine.

In the last 5 weeks we’ve got news on:

- retatrutide, the triple agonist GLP-1 from Lilly, basically melting fat and body-wide inflammation at record levels
- RevMed’s new pancreatic cancer drug showing unprecedented abilities to extend life
- small trial of a one-and-done PCSK9 gene editing therapy for slashing LDL cholesterol
- Mayo’s AI-assisted radiology showing vastly improved cancer detection
- this new therapy for metastatic solid tumors

This stuff is at varying levels of evidence. Retatrutide is ~100% on its way, other stuff needs more clinical trial data. But put it together and we’re maybe on the verge of majorly reducing the mortality of heart disease and cancer, the two leading causes of death in America.

[Ankit Gupta @agupta]

I agree with @JTLonsdale on these suggestions.

I’ll add one more. aggressively expand the most successful public-private partnership in American history: the research university system.

We should 10x the budgets of the NIH and NSF and fund massive dataset buildouts through universities that can be used to power the next gen AI systems. Training on those datasets can be restricted to American entities for a number of years to bolster our industries.

and yes we can reform the parts of academia that need fixing in parallel. There is no world in which America wins in which the majority of new basic science is happening abroad.

[Parth Ingle @parthingle_x]

Shipped

[Dwarkesh Patel @dwarkesh_sp]

Could we get a room-temp superconductor from bio? What about chips built from biological materials?

For decades people have been predicting a material science revolution from biotech. So far it's not panned out.

But George Church, the godfather of modern synthetic biology, believes that will change soon.

[Norn Group @NornGroup]

Half a century ago, a group of visionary US and UK scientists shared seven protein structures in a new public archive called the Protein Data Bank.

Over the decades that followed, that early archive grew into the massive data corpus that enabled AlphaFold.

So how did a tiny archive become one of the most important scientific assets in history?

[TBPN @tbpn]

Marginal Revolution co-creator @atabarrok says if we could get just one Erdős-level-problem breakthrough in medicine out of AI, it would be an enormous deal — and it's well within the realm of possibility.

"We just saw yesterday that AI had proved a new mathematical theorem. So AI is making these inroads into the highest levels of mathematics."

"If we could do that for drug discovery — if we could have a 5% reduction in cancer mortality, that would be worth trillions."

"The opportunities for AI to make tremendous leaps in human welfare by improving medical care are really exciting. And well within the realm of possibility."

[Andrej Karpathy @karpathy]

Personal update: I've joined Anthropic. I think the next few years at the frontier of LLMs will be especially formative. I am very excited to join the team here and get back to R&D. I remain deeply passionate about education and plan to resume my work on it in time.

[Richard Sutton @RichardSSutton]

The bitter lesson in 26 words:

Don’t be distracted by human knowledge, as AI has been historically.
Instead focus on methods for creating knowledge that scale with computation, like search and learning.

[Caleb Watney @calebwatney]

How it started // How it's going

[Cristina Muñoz Pinedo @crismunozp]

I read a paper that was SO WELL DONE. I was impressed. The results were cool, but especially, the paper included all controls that the rest of us ignore - sometimes due to money/time issues, sometimes lazyness.

So I emailed the authors to congratulate them

Reply was emotional

[Jason Meaux @JasonMeaux]

@ihorbeaver Looks great. Do you take in any tactile data or is it vision only?

[Jason Meaux @JasonMeaux]

Wire management can get crazy. Spent 2 hours last week troubleshooting a motor…ended up being a miswired CAN connection. Automated wire harness manufacturing is a great idea!

[Lucas Crupi @lucas_crupi]

@loombotic We’re launching the world’s first quick-turn, high-mix, fully automated wire harness production line.

Our goal is to make wire harnesses as fast and easy to order as PCBs or sheet metal.

Customers can already upload a harness design and get an instant quote. Starting today, these parts can now be produced on our automated line.

We’re starting with Mini-Fit Jr., with more connectors coming soon.

[Casey Handmer @CJHandmer]

Moon mass driver blog post is up: https://t.co/YAI9OAMy4Z

[Anthropic @AnthropicAI]

New Anthropic research: Natural Language Autoencoders.

Models like Claude talk in words but think in numbers. The numbers—called activations—encode Claude’s thoughts, but not in a language we can read.

Here, we train Claude to translate its activations into human-readable text.

[Dylan Morris @Dylan_Morri]

The US needs 1.5 terawatts of new power by 2035.

AI has scaled beyond our ability to build power and the existing power supply chain is the bottleneck

The future demands a new kind of hardware company, building a new kind of Turbine

Introducing: Stone Power @StonePowerUS
🧵1/11

[Jason Meaux @JasonMeaux]

Spent the evening with some friends in Austin thermal imaging actuators under different loads. The delta between coil T and outer housing T can vary a lot, depending on the payload and motion profile. For obvious reasons, brushless motors trap a lot of heat in the windings. Active cooling is going to matter a lot for mobile robots.