PhD student @PetermacCC, Melbourne• MS from @hiv_lab, JNCASR• BSc Zoology from Institute of Science, @bhupro• Interested in studying the Immune System.
I am very proud to share my work on tissue-resident CD8 T cells, induced during pregnancy that can provide lasting protection against breast cancer. This study started at @ONJCRI and was completed at @PeterMacCC.
https://t.co/k4ff6mPOdb
I’m excited to share our latest study, published today in @NatImmunol It has been long known that pregnancy reduces the risk of developing breast cancer, yet the biological mechanisms underlying this protection have remained largely unknown. https://t.co/twfo5yRVOI
An oldie (10 y!) but goodie: cellular interaction at the top! #cellcomm
Video of a T cell (orange) interacting with a target cell (blue)
From Chen et al Betzig (@HHMIJanelia) game changing paper, full https://t.co/tsQY97Pgh1 @focalplane_jcs@cellcommlab#scicomm#microscopy
Beautiful work from #TeamTRM@LMackayLab on revealing retinoic acid as a key factor in establishing immune memory across tissues! This has huge potential for targeted immunotherapies in solid cancers, autoimmunity, etc. Congrats @maxevrard, @obersandreas et al.!!
Most #LaskerAward (s) recognize the thing that was discovered. In Chen’s case, we also recognize HOW he discovered it. His methods are original and breathtaking.
Awards Jury Member Michael Brown honors #LaskerLaureate James Chen
#Lasker2024@UTSWMedCenter
Dear Treg enthusiasts from Melbourne and Victoria, we are organising the 3rd Treg mini-symposium on 11th Nov at @WEHI_research. It a free event with fantastic talks and prizes!! Please register: https://t.co/kJpHPOJfKy
@MonashUni@ONJCRI@TheDohertyInst @UniMelbMDHS
Super excited to share our latest work on the native in-cell organization of the mitochondrial respiratory chain 🥳
Using cryo-electron tomography🔬, we show how the respiratory complexes (and other complexes) are organized inside native mitochondria!
https://t.co/cxHl1j20CJ
Today, I would like to honor the memory of Roger Y. Tsien, who died on August 24, 2016. His legacy lives with all who use his technologies, including calcium sensors, fluorescent proteins, the acetoxymethyl (AM) ester, & many more! #FluorescenceFriday
https://t.co/YdWfBPUOBB
Think you know how granzymes work? Think again! GzmA protects against intestinal Salmonella infection, but GzmB helps Salmonella, and perforin has no role at all. Read about this complex story of the battle between host and pathogen here https://t.co/EwRbPQVtYb Tweetorial below
Amazing study!!! @JeffRathmell and team discover previously unknown immune components underlying various inborn errors of metabolism. #immunometabolism
Congrats to Andrew Patterson for his work using CRISPR screens to find we have vastly underestimated the overlap of Inborn Errors of Immunity and Inborn Errors of Metabolism! Inborn errors of immunometabolism? @VUMC_VCI @VUMCResearch
https://t.co/F9Ija7F9Qe
Sydney Brenner's scathing indictment of modern academia in an obituary for Fred Sanger: "We no longer have a culture that allows individuals to embark on long-term - and what would be considered today extremely risk - projects."
How are Tregs non-inflammatory? A beautiful study in @ImmunityCP from Shimon Sakaguchi and colleagues @osaka_univ_e show that the Foxp3-IKZF1-IKZF3 complex displaces p300 and represses the inflammatory gene expression programs in Tregs https://t.co/j37A19w3uA