All smiles from the @AndreaCercek research team after her ground-breaking presentation. “This has never happened in the history of cancer” from @nytimes https://t.co/XyloeP4IKS
Check out our new publication with @MSKCancerCenter demonstrating #ecDNA - based KRAS G12C amplification as a recurrent resistance mechanism to KRASG12Ci + EGFRi treatment in CRC! https://t.co/6Ntpfug8bN @KRASkickers#oncology
A recent @MSKCancerCenter trial had an unprecedented success rate — and it could have dramatic implications for other cancers: “The tumor’s completely gone.”
🚨 Breaking #ASCO22 News: Breakthrough findings published in @NEJM by MSK experts @AndreaCercek & Luis Diaz show 100% complete response rate in all patients who received #immunotherapy treatment for mismatch repair deficient locally advanced #RectalCancer. https://t.co/xlUfR9CKQz
Very proud of our study published in @NEJM. 100% clinical complete response with dostarlimab alone in mismatch repair-deficient locally advanced #RectalCancer. No radiation or surgery! @ASCO#ASCO22@MSKCancerCenter https://t.co/sZypoHBtj7
All smiles from the @AndreaCercek research team after her ground-breaking presentation. “This has never happened in the history of cancer” from @nytimes https://t.co/XyloeP4IKS
Dr Luis Diaz of @MSKCancerCenter discusses the challenges of how MSS tumors don't respond to ✅ point inhibitors, low TMB and low PDL1 and peritumoral inflammation #crcsm#GIonc#ASCO22
Exciting results out of #ASCO22: The @MSKCancerCenter doctors decided to change the study so that patients would not require radiation, chemotherapy, or surgery. Just six months of immunotherapy treatment was enough by itself. https://t.co/fC57FbjgYy via @statnews
'A complete remission in every single patient is “unheard-of”'
Combining genomics diagnosis of mismatch repair deficient + PD-1 immunotherapy led to complete remission of 18 consecutive patients w/ advanced colorectal cancer https://t.co/54yFGoTDoZ
https://t.co/CZsoFHM0Gl #ASCO22
Now published in @NEJM we describe 100% clinical CR with dostarlimab alone in 12 patients with locally advanced dMMR rectal cancer!Our team leader @AndreaCercek@MSKCancerCenter presenting the data @ASCO#ASCO22
“I believe this is the first time this has happened in the history of cancer,” Dr. Diaz said. Still, the trial will need to be replicated in other patients. https://t.co/EKxUnqpFN9
Well deserved ovation to Dr. @AndreaCercek and the GI Onc team at @MSKCancerCenter . Yes, you’re reading well: 100% cCCR in pts w/ MSI-H / dMMR LA Rectal Cancer w/ IO. This means possibly no need for CT, RT or Surgery! This is a game changer for our patients!