Jessica Gong

Asst. Professor @karolinskainst | brain health, sex difference, biomarkers 🕵🏻‍♀️

[Jessica Gong @JessicaYGong]

If you are a recent data science/biostats or epidemiology PhD graduate or postdoc with interests in sex and gender difference in dementia, and want to come and join Karolinska Institutet in beautiful Stockholm, please get in touch and apply! 🇸🇪🧠

https://t.co/DbX1IBLTsd

[@BrainComms @braincomms]

Gong et al. report that plasma proteins NEFL, RPS6KB1, and MMP12 are linked to future dementia risk; machine learning boosts prediction, highlighting early biomarker potential. Please read at: https://t.co/yJpPOU1eE6 @JessicaYGong @ELSA_Study

[English Longitudinal Study of Ageing @ELSA_Study]

🚨New study: Blood proteins linked to dementia risk

ELSA & UK Biobank data reveal key biomarkers:

📌NEFL & RPS6KB1 linked to dementia
📌MMP12 linked to vascular dementia
📌Possible sex differences in risk

Read the full story: https://t.co/GV57QvJDzE

#Dementia #Ageing

[Anders Martin Fjell @AndersFjell]

Preprint: Using 400k memory tests & 15k brain MRIs, we find no evidence that education enhances cognitive reserve. Edu linearly related to better mem, but not less brain or cogn decline, or more tolerance to atrophy 🧵@LCBC_UiO @LifebrainEU @UiO_LifeSci
https://t.co/uzYgZ8AF4R

[Ming "Tommy" Tang @tangming2005]

Survival analysis is a critical skill for bioinformaticians. Why? It helps stratify patients and identify potential biomarkers. 🧵👇

[Eric Topol @EricTopol]

Plasma proteins and brain aging.
New @NatureAging
Assessment of ~3,000 proteins in ~11, 000 @uk_biobank participants w/ over 11,000 MRI phenotypes
1. Brain aging is non-linear, with protein waves at ages 57, 70 and 78

[Karsten Suhre @ksuhre]

This will be HUGE!

@oxfordnanopore and @uk_biobank to create world’s first epigenetic dataset targeting the causes of cancer, dementia, complex disease https://t.co/2NIjyuSMjt

Learn more about DNA #methylation with #metabolomics and #proteomics here:

https://t.co/BoDGnZncle

[Jessica Gong @JessicaYGong]

@MariosGeorgakis Very cool, excited to see if there will be a longGWAS on cognitive decline in the future! 🧬

[Marios Georgakis @MariosGeorgakis]

GWAS is typically run for cross-sectional traits and not longitudinal trait trajectories📈🧬

👉New paper describes an application of linear mixed models for longGWAS of eGFR decline
👉Modeling function of age with random slopes & intercepts was statistically advantageous

link👇

[Jessica Gong @JessicaYGong]

New pub!💥

Protein signatures associated with loneliness and social isolation: Pl... https://t.co/2iQniPLvnk

[Jessica Gong @JessicaYGong]

Excited to share my book chapter on aspects of sex and gender in disease, grateful for it being the opening chapter for the Handbook of the Behavior and Psychology of disease. ⚖️

https://t.co/MDnoKrvaE4

[Jessica Gong @JessicaYGong]

I am guest-editing a Special Issue for the International Journal of Environmental Research and Public Health!
https://t.co/Mx0PBLjCHy

We welcome research to deepen our understanding of the environmental impact on dementia and cognitive ageing. 🌏🧠

Submit by August 31, 2025.

[The Lancet Reg Health-West Pacific @LancetRH_WPac]

Series: Risk factors for the neurodegenerative dementias in the Western Pacific region

Read the full article here: https://t.co/Io309kmkPM

[Professor Matthew C. Kiernan AM Nerve Centrals @nervecentrals]

Confronting the challenges of an ageing population, #climate change & rapid economic development, offers a compelling case study of the #global phenomenon of population #ageing in addressing #neurodegeneration & #dementia | #WPR #roadmap @magxcite @NerveCentralSYD #AD #ALS #neuro

[The Lancet Reg Health-West Pacific @LancetRH_WPac]

New Comment: Understanding dementia in the Western Pacific: a region-specific approach to prevention

Read the full article here: https://t.co/bmlZXnAMK7

[Biomarkers of Aging Consortium @agingbiomarkers]

🧵 1/8 🎉 Our latest collaborative publication, "Challenges and recommendations for the translation of biomarkers of aging", has just been released in Nature Aging (@NatureAging). Biomarkers of aging predict biological age and its response to interventions but face challenges in clinical translation. Our study identifies six key barriers and provides strategies to overcome them.

[Jessica Gong @JessicaYGong]

Sharing my latest commentary “understanding dementia in the Western Pacific: a region-specific approach to prevention” on the Lancet Regional Health - Western Pacific! 🧠🌏

https://t.co/kiXCGrD9t4…

[Veera Rajagopal  @doctorveera]

Phenome-wide association of APOE alleles across 2,318 EHR-derived phenotypes in 180k participants of the All of Us biobank.

Khajouei et al. medRxiv
https://t.co/h0bmHRNfHC

[The George Institute for Global Health @georgeinstitute]

Women are more likely to develop dementia than men.

But why is this?

A study led by @JessicaYGong involving almost 30,000 people provides clues to the higher risk of the condition in women: https://t.co/dlEypRkZLQ

[Marios Georgakis @MariosGeorgakis]

Most omics studies include single-time assessments and don't capture dynamic changes📈📉

A massive longitudinal multiomics analysis of 108 indviduals:

👉135,239 features
👉median 47 serial assessments over 1.7 y
👉246,507,456,400 total data points❗️

https://t.co/OXS5MLl0gj