Joshua Mast

biologist | amateur bassoonist | dad

[Michael Booth @DrMikeBooth]

We've topologically constrained antisense oligonucleotides into a handcuff structure, via photocages, to control gene knockdown!

Published in @ChemCommun, led by @DenisHartmann
@OxfordChemistry @OxfordSynthesis @UCLChemistry #supramolecular #ASO https://t.co/s8T1JmKIIF

[Lars Krogmann @LarsKrogmann]

This is spectacular 🥹, a parasitoid flat wasp ovipositing in its host beetle larvae in 100 mio year old amber!

👇
https://t.co/Qnmh8oQKRT

[Steve Schmidt @SteveSchmidtSES]

“Trump’s fascist rally was many things: horrifying, un-American & frightening. It’s also a premonition of something growing & darkening. It requires breathtaking naïveté, mixed in a cocktail of delusion, to believe that this isn’t what it appears to be.”https://t.co/wEzfTMZjss

[Joshua Mast @JoshDMast]

Cross bay battle

[Katie Mack @AstroKatie]

Look closely at the "smudges" -- the stretched out swaths seen here as pink-ish streaks. Those are some of the most distant galaxies, with their light stretched and distorted by the gravity of the cluster of galaxies in the foreground, in what we call gravitational lensing. #JWST

[Alyssa A. Goodman @AlyssaAGoodman]

Here's a 1-minute video showing--in the words of visualization hero @EdwardTufte--the "compared to what" factor for today's amazing @NASAWebb image. Thanks to the @WWTelescope for making this possible, and @ADavidWeigel. I only wish @NASA and @POTUS had shown the image this way!

[Nature Biotechnology @NatureBiotech]

B cells are engineered in vivo to secrete anti-HIV antibodies https://t.co/NSuiSdK23O

[Joshua Mast @JoshDMast]

@AnupamAich4 @AcademicChatter If industry science is an option, we’re looking for single cell genomicists

[Gunhild Alvik Nyborg, MD, PhD, Exam. Oecon., FRSM @GANyborg]

Norway is seeing the world’s first omicron superspreader event after a party downtown Oslo last Friday. Of 120 healthy non-symptomatic fully vaccinated individuals with a negative test, two had recently returned from South Africa and turned out to be positive, omicron. 1/

[Arachtober @arachtober]

Welcome to the 15th year of #Arachtober! Celebrate arachnids with us by sharing your photos of spiders, scorpions, and other arachnids all month. We're glad to see growing arachnid enthusiasm around the web!

Banner by @zxgirl and I, with Rhomphaea projiciens, a cobweb spider.

[Joshua Mast @JoshDMast]

We have open positions for great biologists @berkeley_lights! My group is hiring a protein biochemist: https://t.co/wM6ouMHN7P

[Jon Favreau @jonfavs]

Closing strong!

Larry Elder is promising to hand the U.S. Senate to Mitch McConnell and the Republicans if he gets the chance.

Californians, vote NO on the recall and get your damn ballots in: https://t.co/zZm47KOVPi

[Drew Tuma @DrewTumaABC7]

Last 12 hours across California
#DixieFire #CaldorFire

[Eric Topol @EricTopol]

Pretty damn impressive
Thanks Darren Lu @Reddit

[Joshua Mast @JoshDMast]

@axios Our next purchase certainly won’t be a @Toyota.

[drew coffman 𝕚𝕤 𝕠𝕟𝕝𝕚𝕟𝕖 🟢 @drewcoffman]

this illusion broke my brain 🤯

[Dr Ella Hawkins @EllaMcHawk]

I am reliably informed that today is #NationalBiscuitDay.

Here is a 🧵 of all the biscuits I've made so far in 2021.

First up, my William Morris set. Inspired by an old @V_and_A calendar, everything hand-piped in royal icing. Flavour: cardamom, orange & vanilla.

[Thomas Merritt @tjsmerritt]

Role model

[Joshua Mast @JoshDMast]

@sejdevries @ClementYChow I've heard that when they fall off the tree, it knocks the L out of them.