Multidisciplinary journal dedicated to understanding and treating cancers arising from the gastrointestinal tract. Publisher: @springernature. Editor: @jcloydmd
GI Oncology standard regimen doses remain too high for many real world patients. Retrospective and prospective trials demonstrating benefit of reduced doses or dose escalation are accumulating. #meded#gionc#crcsm#pancsm
🚨#TOPGEAR ⚙️ results at #ESMO24
RCT: periop chemo w rads 🆚 no rads
👥 574 gastric/GEJ adenocarcinoma
⬆️ pCR with rads
❌ No difference in OS or PFS 🙅🏻♀️
That settles it then? 🤨
📝👇🏻
Viewpoint by @dahaggstrom, @SigneBraafladt, and Paul K.J. Han describes the benefits and challenges of active surveillance as a clinical approach to monitor low-risk cancers with favorable prognoses. https://t.co/q0Ba0lezEs
From @JAMA_current: Among patients undergoing liver resection for a cancer-related indication, tranexamic acid did not reduce bleeding or blood transfusion but increased perioperative complications. https://t.co/mNvn9x8De2
Systematic review and meta-analysis of the effect of prehabilitation on LOS and functional capacity in pts undergoing resection for CRC. How much is LOS decreased? Read more in this month's #DCRJournal: https://t.co/eazTK0hZRD
@Swexner@me4_so@ACPGBI@drtracyhull@ASCRS_1
Laparoscopic versus open right hepatectomy for colorectal liver metastases after portal vein embolization: international multicentre study @BJSurgery https://t.co/6qSD87itTB
The LASRE trial established the short-term oncologic safety of using laparoscopic surgery for low rectal cancer. The rate of complete total mesorectal excision was practically identical with laparoscopic surgery (85.3%) vs open surgery (85.8%). https://t.co/CTUZ0NULMG #Research
Updated 5-year results of the Unicancer PRODIGE 24/CCTG PA6 trial confirmed the significant improvement in all outcomes, including overall survival, with mFOLFIRINOX regimen compared to gemcitabine in adjuvant setting for pts w #pancreaticcancer. https://t.co/rCFntho0f1 #GICSM
👉Upfront FOLFOXIRI plus Panitumumab does not improve outcome in #CRC now published in @JCO_ASCO
https://t.co/Cxsjgu1rzu
✅TRIPLETE phs-III, 88% left-sided tumors
👉relative "low" ORR, and more GI toxicity
❌more is not always better...
@myESMO@OncoAlert
JCOG1213 (TOPIC NEC), the first randomized phase III trial in advanced neuroendocrine carcinoma of the digestive system, shows no significant difference in overall survival for etoposide+cisplatin versus irinotecan+cisplatin therapy https://t.co/JTELRlzTzi #GICSM
🔥Global burden of cancer attributable to risk factor🔥
@TheLancet
https://t.co/UbFJJ0xbVr
🤔44% of global cancer deaths attributable to risk factors
🧐leading: smoking, alcohol, high BMI
👉Prevention, early diagnosis, effective therapy required
@myESMO@OncoAlert@EASLedu
Look 👀 what arrived in the mail today! Hot off the presses - our new book 📖 Edited by @AEjaz85 & myself, this book brings together 🌎🌏 experts to cover a broad range of topics on management of #colorectalcancer#metastatic#disease. Be sure to ✔️it out!