Julia Sapozhnikov 🇺🇦

Infectious Diseases Clinical Pharmacy Specialist, 🦠 🧫 Loyola University Medical Center

[Julie Ann Justo @julie_justo]

Cefepime/enmetazobactam (Exblifep) approved by @US_FDA yesterday for cUTI & pyelo in adults. Primarily restores cefepime against ESBLs (CTX-M, SHV, TEM) w/ other benefits of cefepime (eg AmpC stability). Not active against KPC, MBLs, OXAs though. #IDTwitter #TwitteRx

[SIDP @SIDPharm]

Link: https://t.co/wVYA4otKom

[Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 @ABsteward]

🆕️⚡️⚡️ @jac_amr
🌟s @marylynnstaicu @Bruce_M_Jones @PharmerMeg @stoverkr @jwagsIDPharmD @blandman19
Penicillin-allergy delabelling resources for clinicians practicing in resource-limited settings: a full educational resource review of the grey literature https://t.co/JOQAXrAukk

[Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 @ABsteward]

Super interesting ⚡️
Voriconazole exposure is influenced by inflammation: a population pharmacokinetic model
▶️CRP influences voriconazole exposure
▶️Voriconazole metabolic rate decreases 50% for every 150 mg/L increase in CRP #IDTwitter
https://t.co/TSnpJYxG6Y

[Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 @ABsteward]

🆕️⚡️Review #IJAA
Dalbavancin as sequential therapy for infective endocarditis due to Gram-positive organisms #IDTwitter #IEWikiguidelines @DrToddLee
@BradSpellberg
https://t.co/VrMaXOGR9J

[Keenan L Ryan @keenanconazole]

Congrats to my #OPAT peeps @johnsontannerm @MsSmallsO @mmPharmD @corevalues5 @UNMHSC attending Dr Byrd (twitterless) and @jeffpears0n What a great article!

[Holly Frost @HFrostLab]

Ways to deal with an amox shortage:
1. Don’t prescribe amox for viruses
2. Don’t prescribe amox for bacterial infections that are unlikely to benefit (eg many kiddos with acute otitis media)
3. Use the shortest duration needed.

Things not to do:
Blindly switch to cefdinir

[Melissa Johnson @IDPharmacist]

Heard about the amoxicillin shortage? SIDP has thoughts... @AAPNews @PIDSociety @IDSAInfo @SHEA_Epi @pharmacists @SIDPharm @ACCP @ASHPOfficial @TracyZembles @OncIDPharmd @jwagsIDPharmD @bergmanscott @ae_gross @IDPharmD_Kate #WAAW2022 #IDTwitter @https://sidp.org/news/12978701

[Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 @ABsteward]

🆕⚡⚡Narrative review @CMIJournal @DoctorRachael @medrants @BradSpellberg
Short course antibiotics for common infections: what do we Know and where do we Go from Here? #IDtwitter #medtwitter #TwitteRx #MedEd #Shorterisbetter
https://t.co/42WQVtWkRX

[Brad Spellberg @BradSpellberg]

Updated Oral vs. IV Abx tables, per suggestion of @ABsteward. Some important points.
1) Tables only list Oral vs. IV-only abx trials. Turns out, oral is so common for peds osteo that there are no studies where the control arm got IV-only Tx.

https://t.co/F9Whl43PhE

[Deeksha J. Ladani, MD @transplantID]

Probs one of the best review articles I've read. @DrLuisO @ClancyNeil @FungalDoc @DrPappasID , DPK , @ElMylonakis

[Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 @ABsteward]

🔥🔥Just Published🔥🔥
@JAMANetworkOpen
The 1st EVER ID #WikiGuidelines
Lead @bradspellberg @DrToddLee
I was honored to participate w 63 clinicians,8 countries
🌟Clinical Guidelines for the management of pyogenic osteomyelitis in adults🌟 #IDTwitter https://t.co/j2ijKB2OhG

[ACCP INFD PRN @accpinfdprn]

🚨 Check out 2022 ISPD Peritonitis Guidelines with updated recs regarding empirical abx selection and dosage of antibiotics. Also new recs regarding adjunctive oral N-acetylcysteine therapy for mitigating AG ototoxicity. @SIDPharm @ACCP #IDTwitter
https://t.co/QFMoMB0v4g

[Julia Sapozhnikov 🇺🇦 @JuliaPharm]

@BrianHoff_ Haha OSH is literally the worst

[ASHE Journal @ASHE_Journal]

New from @JoergerTorsten @LPthePharmD @StanfordPedsASP: This review summarizes the impact of the #COVID19 pandemic on antimicrobial #stewardship programs and the efforts antimicrobial stewardship programs have contributed towards the pandemic response
https://t.co/UJqsPAz9Xe

[Antibiotic Steward Bassam Ghanem 🅱️C🆔🅿️🌟 @ABsteward]

🆕💥💥Narrative review @Crit_Care @jfbarletta
described the literature pertinent to drug dosing in obesity as it applies to #COVID19 related therapies with a focus on medications recommended by NIH for hospitalized adults #IDTwitter #TwitteRx #MedEd
https://t.co/t2SIJKvRpU

[Hillary Clinton @HillaryClinton]

I want to thank the Russian Academy for this Lifetime Achievement Award.

[Matt Davis @MattDavis138]

Happy this one is up! We added our experience with opened isavuconazole caps and crushed DR posaconazole tabs w/ TDM in pts who couldn't swallow. Most patients were able to achieve targets, but careful TDM is a must.

Hope this can spare some IV therapy.

https://t.co/eAKazhI8jI