Happy 3rd Anniversary to Whiteout Survival!
Three years of surviving the frost, building cities, and fighting together with allies around the world.
Here’s to many more years of adventure in the frozen wasteland! ❄️⚔️
#whiteoutsurvival#wos3ndanniversary
ID: 656510190
🩸 Ácido tranexámico: Revisión ilustrativa.
Completa y menciona los artículos más relevantes respecto a la evidencia de su uso.
Gratis
https://t.co/erLKMepTz3
🔴 DOACs should not be the standard treatment for patients with mechanical heart valves, #AFib , rheumatic mitral stenosis or antiphospholipid syndrome
📍Read key points from a #JACC state-of-the-art review on when DOACs should not be standard treatment https://t.co/IfLL9pqObz
1/ Published today: The updated evidence-based recommendations for managing Lower Extremity PAD, originally outlined in the 2016 Guideline, now incorporate the latest research findings to assist clinicians.
✍🏽:@heatherlgornik
📖: @CircAHA
Highly convincing data from @brendonneuen and SMART-C that use of GLP-1 RA neither affects the efficacy, nor the safety, of SGLT-2 I.
https://t.co/gwGtaCLgKR
After FLOW comes the question whether SGLT-2 I affects the efficacy of GLP-1 RA.
1/ Richard Pratley @RpratleyMD talking about design #ERA24
🔸 randomized, double-blind, parallel-group, multinational, phase 3b trial
🔸randomized 1:1 to once weekly semaglutide 1.0 mg or matched placebo,
💉once weekly subcutaneous semaglutide versus placebo
🔸 event-driven trial
🔸Included countries from all the continents
We are pleased to announce the publication of the KDIGO 2024 Clinical Practice Guideline for the Management of Antineutrophilic Cytoplasmic Antibody (ANCA)-Associated Vasculitis, published today in the March issue of Supplement to Kidney International, with an Executive Summary in the main pages of the journal.
Read the news release: https://t.co/ewZokps7wF
Read the guideline in Kidney International: https://t.co/M9Y1QBeS6s
Visit the KDIGO ANCA Vasculitis Website: https://t.co/oBR5IPukpe
Developed under the stewardship of Co-Chairs Brad Rovin, MD (US) and Jürgen Floege, MD (DE), this guideline is an update to the ANCA Vasculitis chapter of the KDIGO 2021 Clinical Practice Guideline for the Management of Glomerular Diseases.
"The ANCA Vasculitis Guideline includes significant updates aimed at enhancing clinical decision-making, integrating new treatments with established clinical practices," stated Dr. Floege. "We anticipate that the comprehensive research, clinical perspectives, and collaborative expertise reflected in this guideline will contribute to better outcomes for individuals grappling with this complex condition."
"We are excited to release the KDIGO 2024 ANCA Vasculitis Guideline, which offers new guidance for managing the intricacies of ANCA vasculitis treatment, particularly with the emergence of innovative therapies," said Dr. Rovin. "We are better equipped than ever to tailor interventions, optimize patient care, and strive towards improved outcomes for people with ANCA-associated vasculitis."
KDIGO thanks the Guideline Work Group for their dedication and expertise and the Evidence Review Team from Brown University School of Public Health for their comprehensive work on this guideline.
#ANCA #vasculitis #AAV #glomerular
‼️SELECT trial - Semaglutide 2.4mg in those with obesity/overweight 🚫diabetes‼️#AHA2023
🔹Inclusion: >45yrs, BMI >27, eASCVD (stroke/MI/symptomatic PAD)
🔸mean age 61.6, BMI 33.3, 72% male
🔹PEP : 3P MACE - achieved!
HR 0.80, p<0.001
🔸Just missed CV mortality p0.07… interesting trend 🤔 so 2ndry outcomes - pinch of 🧂
🔹Numerical reduction hHF (expected but interesting to see details)
🔸Numerical reduction all cause mortality (again- details will be interesting!)
🔹Nonetheless - first CVOT incretin trial in those without diabetes shows benefit! Implications for clinical care!
Stay tuned for more from us!
https://t.co/6NfcafUeYS
@kamleshkhunti@DLBHATTMD@AmarPut@drpatrickholmes@dr_amritlamba@mmamas1973@DrRaniKhatib@redGDPS@kaulcsmc@BevTchangMD
In a study with 17,604 patients, #semaglutide showed a significant reduction in major CV events compared to placebo (6.5% vs 8.0%, HR 0.80, P<0.001) over ~40 months.
There were no unexpected safety findings, although well-known GI side effects drove a higher rate of permanent treatment discontinuation in the semaglutide arm (16.6% vs 8.2%; P < 0.001)
https://t.co/rvFIiBJusY @NEJM #AHA23
2023 ESC Guidelines on ACS: what is new in antithrombotic therapy? | European Heart Journal - Cardiovascular Pharmacotherapy #EHJCVP#SAPT#DAPT#PreTx https://t.co/6LKO6BH1lZ