DNA-binding affinity and specificity determine the phenotypic diversity in BCL11B-related disorders: The American Journal of Human Genetics https://t.co/xsSzZDfbXs
Vor 32 Jahren habe ich die Ursache einer Erbkrankheit entdeckt. Jetzt hat mir AlphaFold gesagt, warum die Mutation krank macht. https://t.co/XRIQEmBmfz
I am glad to share our latest work, identifying variants in the LRRC7 gene as a major cause for intellectual disability, autism, aggression and abnormal eating behaviors. Thanks to members of my group and all 57 coauthors!
https://t.co/GPlaOa9B6I
Shankology. Some things should not be separated. Especially true for SPN and Ank of Shank3, as shown here in work from 3 generations of PhD students. https://t.co/STX8fGfvlQ
The so-called "Mexican drug problem" is an AMERICAN problem.
Who do you think buys this shit?
Who do you think consumes this shit into the trillions of dollars?
The entire 50 year+ war on drugs is a MASSIVE LIE.
EMBL Hamburg’s SPC Facility emphasises providing reliable and excellent quality data for its users, including those without a background in biophysics.
Big thanks to our users Mary, Katharina, and Jacek, who explain in the video how the facility helped them in their research.
📢
Our latest collaboration with UKE and among showing how structural conformations of Shank2 protein variants are affecting postsynaptic interactions towards neural disorders 🧠🔎
@UKEHamburg@embl@EMBLHamburg@CssbHamburg@unihh
More below 👇🏽
https://t.co/WdfRkNRUMu
Synaptic Shank polymerizes via SAM domains, and binds SAPAP/GKAP via PDZ domains. Is this important for human health? Find out in our new paper in Mol Psychiatry. Thanks to SPC@EMBL Hamburg and AG Lohr (Biology, Uni Hamburg). https://t.co/gfv1DIjRek. #cureShank
Check out this new article in LSA!
Patient missense variants in CASK interfere with binding to, and regulation of condensate formation of Liprin-alpha 2.
@KreienkampL
https://t.co/Bu1MM909Py