Associate Professor @Yale Immunobiology and Center for Systems and Engineering Immunology. Interested in understanding and engineering immune cell circuitry.
So proud to share our work on memory T cell generation, now out in @ImmunityCP! This huge paper is the heroic work of @kathleenabadie, @elisacclark and Raj Valanparambil from @rafiahmed_lab.
It’s a big day for us today as we share the @Kueh_Lab’s latest work, just out in @ImmunityCP . We set out to understand how memory T cells form, and we found remarkable flexibility in their lineage pathways from naive progenitors: https://t.co/P6VZKMYjJP
Trump's proposal is ILLEGAL & amounts to an indiscriminate funding cut for research centers of all sizes, NOT just Ivies. It will mean shuttering labs across the country, layoffs in red & blue states, & derailing lifesaving research on everything from cancer to opioid addiction.
NIH indirect costs fund the backbone of research: maintaining labs, ensuring safety, and supporting admin work. These are essential for groundbreaking discoveries. Drastic cuts to NIH indirect rates are detrimental to academic biomedical research.
NIH has announced a cut in the "indirect rate" to 15% across the board, in a move that appears to be retroactive to even existing grants. This is a bloodbath for research institutions throughout the country.
Brief explainer for those not in this world:
https://t.co/VUP7tWat7O
Excited to share my PhD work from @rafiahmed_lab. We show how CD8 T cells overcome the inability to predict how long a viral infection will last by making adaptable precursor cells a priori—an elegant strategy for an inherently non-prescient immune system. https://t.co/etxUUtbQg2
Second edition of the EMBO workshop on Developmental Timing across species.
Second edition organized by @bassemh1@MDiazCuadros @VanderhaeghenP2 and I. #EvoDevoTempo
Cool speakers & fun networking activities organizers.
More details coming soon. Save the date!
Calling all faculty candidates (postdocs, Asst Profs, senior grad students) - Apply to @UWBioE! Job ad at link below. If you are considering applying and have questions on the ad, please email or DM me. Come join us, UW is amazing! https://t.co/SaWp9k7nsD
🚨𝐇𝐞 𝐋𝐚𝐛 job opportunity @UCSF 🚨:
I'm hiring TWO postdocs - an experimentalist and a computational biologist. Join us to use cutting-edge single-cell and spatial technologies to unravel the mysteries of human tissues.
https://t.co/QJqxMmrxGi
What if you could find out the history of signaling activity in each cell with a single round of imaging? Wouldn't that be incredible? Well, we thought so too. And that's what we set out to achieve with INSCRIBE in our new preprint. Let’s dive in! 🚀🔬
https://t.co/J634soGHwz
Excited for the Keystone Symposium on T Cell Differentiation in Tissue Microenvironments. #KSTCells25
Submit your abstract by Nov 5th for a chance of being selected for a short talk!
Joint meeting w Innate Memory
Keystone!
https://t.co/Cbn64XGkJt
Princeton's new Omenn-Darling Bioengineering Institute (@omenndarlingbio) is running multiple faculty searches this year! We are really excited to grow our bioengineering faculty & move into a brand-new building. Postdocs on the market - apply at: https://t.co/r9tm4veznv
1/12 Check out this paper that came out last week from our pan-monogenic project, which utilizes diverse natural single-gene defects in humans to study and assess the immune health of both patients with disease or those clinically healthy.
https://t.co/4VOsJMCgIc
Our latest preprint which is the result of ~8 years of collaboration with the @TheHPAP is now available on bioRxiv. Our work represents the largest existing multiome measurement in pancreatic lymph nodes of humans in health and Type 1 Diabetes:
https://t.co/cbTIyRRnBw
🚨🚨🚨🚨
Our new preprint is out!
“Pre-existing stem cell heterogeneity dictates clonal responses to acquisition of cancer driver mutations”
🩸🧫🧪🧬
https://t.co/CYOsKcssPy
The superteam of @cancer_curious and Dani Fernandez tackled a major unanswered question in HSC bio.
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