Lauren Burgeno, PhD 🇺🇸➡️🇬🇧👩‍🔬🧠💉🔬🧀🍺

Behavioral Neuroscientist @UniofOxford. Dan Norman Early Career Fellow @BalliolOxford, Former NSF Postdoc Fellow, & @UCIrvine / @UW Alum. She/Her

[Lauren Burgeno, PhD 🇺🇸➡️🇬🇧👩‍🔬🧠💉🔬🧀🍺 @LBurg]

🥳🍾🍺Celebrating my first *1st author paper finally being up after way too many years!! No time for a twitter thread explainer now, but soon! Big shout out to co-lead author @RFarero , PhD supervisor @PaulEMPhillips and rest of our team for guidance & help along the way!

[bioRxiv Neuroscience @biorxiv_neursci]

Cocaine Seeking And Taking Are Oppositely Regulated By Dopamine https://t.co/0r7EKOoSkD #biorxiv_neursci

[Olivier George @brainaddiction]

Couldn’t agree more! We need to 10x polysubstance use research funding. We actually need whole research centers dedicated to basic research on polysubstance use. Right now they are almost all exclusively dedicated to a single substance.

[Lauren Burgeno, PhD 🇺🇸➡️🇬🇧👩‍🔬🧠💉🔬🧀🍺 @LBurg]

@brainaddiction oops! Just realized I managed to comment on your post without it actually being a reply in the thread 🫣😳- https://t.co/ktL3PKq5Nv

[Lauren Burgeno, PhD 🇺🇸➡️🇬🇧👩‍🔬🧠💉🔬🧀🍺 @LBurg]

@brainaddiction thanks for the shout out! It didn't make it into the paper, but it doesn't seem that tolerance explains the diminished DA during drug taking as the total cumulative infusions earned doesn't significantly differ at week 3-4 btw groups. 1/2

[Lauren Burgeno, PhD 🇺🇸➡️🇬🇧👩‍🔬🧠💉🔬🧀🍺 @LBurg]

@brainaddiction Early on I spent some time looking at whether diffs in patterns of intake ( steady vs. bursts) might produce different dynamics in brain cocaine levels that could explain diffs in DA, but I am not sure my computational approach was ideal, so would be worth revisiting!

[Lauren Burgeno, PhD 🇺🇸➡️🇬🇧👩‍🔬🧠💉🔬🧀🍺 @LBurg]

@brainaddiction The escalators start with lower intake initially and this escalates over weeks, whereas escalators start a bit higher and maintain stable intake so overall the number of infusions ( and drug-cue pairings) don't differ.

[Drug Monkey @drugmonkeyblog]

Lauer is super concerned about the demoralizing impact of low success rates...now that it is white folks being affected https://t.co/ciEl94XghU via @drugmonkeyblog

[Jose Moron-Concepcion. @jomoronc]

Our new paper in collaboration with Bill Carlezon and @ErikMusiek on the effects of pain on sleep architecture is now out at @npp_journal .
Work done by the amazing @DominikaJBurek and @khairunisa_ibk
https://t.co/SayKICzBYp

[Michael A. Taffe @effatma]

I missed your statement on the attacks on Diversity, Equity and Inclusion activities of the NIH. Could you re-post the link, please?

[Dan Neidle @DanNeidle]

There are companies worth £50bn* based in this terraced house in Bolton.

Turns out they also have a bank. With a valid VAT registration number.

(*on paper)

[Lauren Burgeno, PhD 🇺🇸➡️🇬🇧👩‍🔬🧠💉🔬🧀🍺 @LBurg]

@mohebial I’m so sorry to hear of your loss. Sending all the love and hugs to you and your family Ali.

[Lauren Burgeno, PhD 🇺🇸➡️🇬🇧👩‍🔬🧠💉🔬🧀🍺 @LBurg]

@FabNaneix

[Lauren Burgeno, PhD 🇺🇸➡️🇬🇧👩‍🔬🧠💉🔬🧀🍺 @LBurg]

@FabNaneix

[Josh Goldberg Lab 🇮🇱💔 @GoldbergLab]

New preprint w/ @lab_plotkin about cholinergic interneurons causing local serotonin release in striatum and how this is related to obsessive-compulsive disorder
https://t.co/h1W6zaC61J
For the story, read on 1/9

[Lauren Burgeno, PhD 🇺🇸➡️🇬🇧👩‍🔬🧠💉🔬🧀🍺 @LBurg]

@nanopharmNC

[Lauren Burgeno, PhD 🇺🇸➡️🇬🇧👩‍🔬🧠💉🔬🧀🍺 @LBurg]

@KordingLab Ive mainly switched to python, but the amount of time spent dealing with package conflicts after updates where my 10 year old Matlab code still runs perfectly sometimes gives me think about my choices

[Ross Tate @rossetate]

As the author of this PDF, it's been interesting seeing people guess at the rationale behind its design. However, the rationale had nothing to do with theory vs practice, and everything to do with pragmatically coping with an unaccommodated disability in academia. (1/16)

[Lauren Burgeno, PhD 🇺🇸➡️🇬🇧👩‍🔬🧠💉🔬🧀🍺 @LBurg]

@GoldbergLab @KamalaHarris @Tim_Walz Thanks for reminding me, I need to do the same tomorrow!!!

[Lauren Burgeno, PhD 🇺🇸➡️🇬🇧👩‍🔬🧠💉🔬🧀🍺 @LBurg]

@The_Koya_Lab

[Lauren Burgeno, PhD 🇺🇸➡️🇬🇧👩‍🔬🧠💉🔬🧀🍺 @LBurg]

@mohebial @Jackie_Gio We also use the relyx cement in A2 shade , but we build the whole headcap from it so maybe like 7 mice per syringe. We put down a layer of optibond first then use relyx

[Lauren Burgeno, PhD 🇺🇸➡️🇬🇧👩‍🔬🧠💉🔬🧀🍺 @LBurg]

@mohebial