Mark Moehle Lab

Assistant Professor @UF_Pharmacology/@UFCTRND. Defining synapses & circuits altered in CNS disorders. Opinions are my own. Former @WCNDD_TN @DukeWestLab/@uabsom

[Norman Fixel Institute for Neurological Diseases @FixelInstitute]

A milestone this PD Awareness Month: The National Plan to End Parkinson’s creates a coordinated strategy to prevent, treat, and ultimately cure Parkinson’s and related disorders.
We are Proud to share Dr. Michael Okun will serve on the Advisory Council helping guide this effort.

[Mark Moehle Lab @LabMoehle]

Excited to get this @MichaelJFoxOrg funded work out there finally! This is very exciting data, and we are actively seeking industrial partners to continue this work.

[Nicole Chambers, PhD @Nicholinergic]

Excited to share my recent first author publication from my postdoc in @LabMoehle ! ⬇️⬇️⬇️ We investigated postive allosteric modulation of M5 muscarinic acetylcholine receptor in the 6-OHDA lesioned mouse model 1/n

https://t.co/FypquuvoLU

[Jonathan Basile @jonothingEB]

It can download pdfs and never read them?

[UF_Pharmacology @UF_Pharmacology]

We are pleased to announce Dr. Mark Moehle, Ph.D., has been awarded ASPET's 2026 Division for Neuropharmacology Early Career Award! 🎉 Please join us in congratulating Dr. Moehle for this achievement!

[Mark Moehle Lab @LabMoehle]

@may_khanna @UF_Pharmacology Thanks @may_khanna !

[allen institute @AllenInstitute]

Join us on Dec. 2 for a webinar on the major advances in basal ganglia mapping, including cross-species cellular mapping and open-access visualization tools.

📅 Dec. 2, 9-10:30am PT
📍 Online
🔗 Register: https://t.co/G7CpRr18pw

#studyBRAIN #BICAN

[Michael 英泉 Eisen @mbeisen]

Finally, someone has solved a real problem with AI! No more having to take a paper in the format for a journal that rejected you, and reformat it for a new journal. Well done!!

https://t.co/J5HekY1Pc0

[Dr. Michelle Bedenbaugh @DrMBede]

My department is hiring! Come join a cutting-edge and collaborative environment. Details below:

[University of Florida Department of Neuroscience @UFNeuroscience]

Happy Postdoc Appreciation Week.

[Mark Moehle Lab @LabMoehle]

Wooooo!! Congrats to Jessi from this prestigous award from @SfNtweets Check out her cool work from the lab at SFN in San Diego!

[Mark Laubach @laubach_mark]

The Neuroscience Dept at American University is hiring for a tenure-track position at the Assistant level and with expertise in Computational Neuroscience. Apply by Sep 15:
https://t.co/Jnrwvr7GBP
#FacultyJobs #AcademicJob #Neuroscience #CompNeuro #AI #ComputationalPsychiatry

[Mark Moehle Lab @LabMoehle]

Proud of all three trainees from the lab for winning awards for their posters and talks!!

[UF McKnight Brain Institute @UFMBI]

180+ neuroscientists & trainees from across US & abroad discussed latest research in Alzheimer’s, Parkinson’s, ALS, dementia @UF-hosted International Research Conference on Neurodegenerative Diseases July 9-12, co-sponsored by the MBI.

Learn more: https://t.co/nLr0kzylho

[nature @Nature]

Researchers funded by the NIH will be required to make their scientific papers available to read for free as soon as they are published

https://t.co/K704HXnyoD

[Mark Moehle Lab @LabMoehle]

Proud to be a part of the @TylersHope think tank on dystonia today! Rick and Emily at the foundation did an outstanding job with the @FixelInstitute team to bring together an incredible team of clinicians and scientists to find the cure

[Tyler's Hope @TylersHope]

2025 Dystonia Think Tank. Energized for moving the needle after a lively, passionate collaboration of top scientists

[Simons Foundation @SimonsFdn]

Applications are now open for the Shenoy Undergraduate Research Fellowship in Neuroscience (SURFiN) program for the 2025–26 academic year. The SURFiN program aims to spark and sustain interest in neuroscience among undergraduate students who have not had access to research opportunities. The paid fellowships will run from Sept 2025 - May 2026. Deadline to apply: May 1. For more info: https://t.co/EPXAj5dTRd

[Ali Nourizonoz @AliNouriz]

Very excited to share BlueBerry, our publicly available, multichannel wireless optogenetic device for freely moving rodents!
Visit https://t.co/HlL4X6sVRW for documentation, and see our preprint for details: https://t.co/v0BpnEWtkg

[PhRMA Foundation @PhRMAfoundation]

#PhF25 awardee Dr. Erick Rodriguez-Palma @UF_Pharmacology is evaluating a novel compound for the treatment of #fibromyalgia. He will study whether it reduces pain behaviors in male & female mice with fibromyalgia induced by chronic restraint stress.
https://t.co/4hEQDktyWj

[UF Medicine @UFMedicine]

🔬 @LabMoehle studies the circuitry and behaviors behind symptoms of movement disorders like Parkinson’s and dystonia at @UF. With @NIH support, translating #UFMedResearch into novel therapies advances treatment for these diseases and drives discovery worldwide.

[Mark Moehle Lab @LabMoehle]

It's really out now!

[bioRxiv Neuroscience @biorxiv_neursci]

Pathological α-Synuclein Perturbs Nuclear Integrity https://t.co/8auK7JLSR9 #biorxiv_neursci

[Mark Moehle Lab @LabMoehle]

This work would not have been possible without funding from @NIH @NIH_NINDS, the Harry T Mangurian Foundation, @UFMBI and the incredible environment @UFMedResearch @UF_Pharmacology and @fi

[Mark Moehle Lab @LabMoehle]

New @LabMoehle preprint from rockstar grad student (and looking for a job) Michael Millett! Synuclein in the nucleus has remained controversial for multiple reasons. Here we use super resolution and expansion microscopy to help answer this controversy

https://t.co/nE3TsYBrKn

[Mark Moehle Lab @LabMoehle]

Taken together, this work shows that aggregation of synuclein causes physical damage to the nuclear membrane, which results in nuclear dysfunction, and that this is a toxic gain of function of pathological synuclein.